SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5l9o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D0V_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5l9o DEOXYFRUCTOSYL-AMINO
ACID TRANSPORTER
PERIPLASMIC BINDING
PROTEIN
(Agrobacterium
fabrum) 		4 / 8 THR A 140
GLY A 144
LEU A 190
GLY A 193
 None
 0.75A 1d0vA-5l9oA:
undetectable		 1d0vA-5l9oA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXY_A_SAMA6734_0
(N-LYSINE
METHYLTRANSFERASE
SETD6)		 5l9o DEOXYFRUCTOSYL-AMINO
ACID TRANSPORTER
PERIPLASMIC BINDING
PROTEIN
(Agrobacterium
fabrum) 		5 / 12 VAL A 110
ALA A 111
GLY A  50
LEU A 243
TYR A 131
 None
 1.03A 3qxyA-5l9oA:
undetectable		 3qxyA-5l9oA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RC0_A_SAMA484_0
(N-LYSINE
METHYLTRANSFERASE
SETD6)		 5l9o DEOXYFRUCTOSYL-AMINO
ACID TRANSPORTER
PERIPLASMIC BINDING
PROTEIN
(Agrobacterium
fabrum) 		5 / 11 VAL A 110
ALA A 111
GLY A  50
LEU A 243
TYR A 131
 None
 1.04A 3rc0A-5l9oA:
undetectable		 3rc0A-5l9oA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RC0_B_SAMB480_0
(N-LYSINE
METHYLTRANSFERASE
SETD6)		 5l9o DEOXYFRUCTOSYL-AMINO
ACID TRANSPORTER
PERIPLASMIC BINDING
PROTEIN
(Agrobacterium
fabrum) 		5 / 12 VAL A 110
ALA A 111
GLY A  50
LEU A 243
TYR A 131
 None
 1.04A 3rc0B-5l9oA:
undetectable		 3rc0B-5l9oA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DX3_A_ESTA601_1
(ESTROGEN RECEPTOR)		 5l9o DEOXYFRUCTOSYL-AMINO
ACID TRANSPORTER
PERIPLASMIC BINDING
PROTEIN
(Agrobacterium
fabrum) 		5 / 10 ALA A 168
GLU A 169
LEU A 177
GLY A 153
LEU A 151
 None
 1.36A 5dx3A-5l9oA:
undetectable		 5dx3A-5l9oA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 5l9o DEOXYFRUCTOSYL-AMINO
ACID TRANSPORTER
PERIPLASMIC BINDING
PROTEIN
(Agrobacterium
fabrum) 		5 / 10 ALA A 168
GLU A 169
LEU A 177
GLY A 153
LEU A 151
 None
 1.32A 5dxbA-5l9oA:
undetectable		 5dxbA-5l9oA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WGQ_A_ESTA601_1
(ESTROGEN RECEPTOR)		 5l9o DEOXYFRUCTOSYL-AMINO
ACID TRANSPORTER
PERIPLASMIC BINDING
PROTEIN
(Agrobacterium
fabrum) 		5 / 9 ALA A 168
GLU A 169
LEU A 177
GLY A 153
LEU A 151
 None
 1.32A 5wgqA-5l9oA:
undetectable		 5wgqA-5l9oA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X24_A_LSNA503_1
(CYTOCHROME P450 2C9)		 5l9o DEOXYFRUCTOSYL-AMINO
ACID TRANSPORTER
PERIPLASMIC BINDING
PROTEIN
(Agrobacterium
fabrum) 		4 / 6 PHE A 264
PRO A 265
GLY A 266
THR A 267
 None
None
None
EDO  A 306 (-4.6A)
 0.89A 5x24A-5l9oA:
undetectable		 5x24A-5l9oA:
18.52