SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5lb3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KGL_A_RTLA175_0
(CELLULAR
RETINOL-BINDING
PROTEIN TYPE I)		 5lb3 ATP-DEPENDENT DNA
HELICASE Q5
(Homo
sapiens) 		5 / 12 PHE B 138
LEU B 179
ALA B 133
ILE B  74
LEU B 112
 None
 1.21A 1kglA-5lb3B:
undetectable		 1kglA-5lb3B:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA141_0
(LYSOZYME C)		 5lb3 ATP-DEPENDENT DNA
HELICASE Q5
(Homo
sapiens) 		4 / 6 ASP B 353
GLY B 354
PRO B 356
SER B 357
 None
 0.78A 1n4fA-5lb3B:
undetectable		 1n4fA-5lb3B:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S19_A_MC9A500_0
(VITAMIN D3 RECEPTOR)		 5lb3 ATP-DEPENDENT DNA
HELICASE Q5
(Homo
sapiens) 		5 / 12 VAL B  76
ILE B 128
TYR B  62
LEU B 183
LEU B 151
 None
 1.12A 1s19A-5lb3B:
undetectable		 1s19A-5lb3B:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J5M_A_ACTA1321_0
(CHLOROPEROXIDASE)		 5lb3 ATP-DEPENDENT DNA
HELICASE Q5
(Homo
sapiens) 		4 / 6 LEU B 179
ILE B  74
VAL B  76
ALA B 133
 None
 1.04A 2j5mA-5lb3B:
undetectable		 2j5mA-5lb3B:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1161_1
(ALLERGEN ARG R 1)		 5lb3 ATP-DEPENDENT DNA
HELICASE Q5
(Homo
sapiens) 		4 / 5 VAL B 162
TYR B 173
VAL B 156
ASP B 157
 None
None
None
MG  B 503 ( 4.0A)
 1.16A 2x45A-5lb3B:
undetectable		 2x45A-5lb3B:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1161_1
(ALLERGEN ARG R 1)		 5lb3 ATP-DEPENDENT DNA
HELICASE Q5
(Homo
sapiens) 		4 / 5 VAL B 162
TYR B 173
VAL B 156
ASP B 157
 None
None
None
MG  B 503 ( 4.0A)
 1.10A 2x45C-5lb3B:
undetectable		 2x45C-5lb3B:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLD_A_ASCA130_0
(CYTOCHROME C')		 5lb3 ATP-DEPENDENT DNA
HELICASE Q5
(Homo
sapiens) 		4 / 5 ALA B 414
GLY B 430
CYH B 431
HIS B 433
 None
None
ZN  B 501 (-2.4A)
None
 1.42A 2yldA-5lb3B:
undetectable		 2yldA-5lb3B:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLG_A_ASCA130_0
(CYTOCHROME C')		 5lb3 ATP-DEPENDENT DNA
HELICASE Q5
(Homo
sapiens) 		4 / 5 ALA B 414
GLY B 430
CYH B 431
HIS B 433
 None
None
ZN  B 501 (-2.4A)
None
 1.43A 2ylgA-5lb3B:
undetectable		 2ylgA-5lb3B:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC507_1
(PHOSPHOLIPASE A2)		 5lb3 ATP-DEPENDENT DNA
HELICASE Q5
(Homo
sapiens) 		4 / 7 VAL B  41
VAL B  42
GLY B  44
PRO B 187
 None
 0.87A 3bjwC-5lb3B:
undetectable		 3bjwC-5lb3B:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_1
(PHOSPHOLIPASE A2)		 5lb3 ATP-DEPENDENT DNA
HELICASE Q5
(Homo
sapiens) 		4 / 8 VAL B  41
VAL B  42
GLY B  44
PRO B 187
 None
 0.86A 3bjwA-5lb3B:
undetectable		 3bjwA-5lb3B:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZY_D_BRLD478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5lb3 ATP-DEPENDENT DNA
HELICASE Q5
(Homo
sapiens) 		4 / 4 ILE B  83
GLN B  63
ILE B 128
LEU B  93
 None
 1.12A 3dzyD-5lb3B:
undetectable		 3dzyD-5lb3B:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_B_TA1B502_1
(TUBULIN BETA CHAIN)		 5lb3 ATP-DEPENDENT DNA
HELICASE Q5
(Homo
sapiens) 		5 / 10 VAL B 203
ASP B 202
LEU B 191
THR B  54
GLN B 345
 None
None
None
ADP  B 502 (-4.1A)
None
 1.50A 3j6gB-5lb3B:
undetectable		 3j6gB-5lb3B:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_D_TA1D502_1
(TUBULIN BETA CHAIN)		 5lb3 ATP-DEPENDENT DNA
HELICASE Q5
(Homo
sapiens) 		5 / 10 VAL B 203
ASP B 202
LEU B 191
THR B  54
GLN B 345
 None
None
None
ADP  B 502 (-4.1A)
None
 1.49A 3j6gD-5lb3B:
1.7		 3j6gD-5lb3B:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_F_TA1F502_1
(TUBULIN BETA CHAIN)		 5lb3 ATP-DEPENDENT DNA
HELICASE Q5
(Homo
sapiens) 		5 / 10 VAL B 203
ASP B 202
LEU B 191
THR B  54
GLN B 345
 None
None
None
ADP  B 502 (-4.1A)
None
 1.49A 3j6gF-5lb3B:
1.7		 3j6gF-5lb3B:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_H_TA1H502_1
(TUBULIN BETA CHAIN)		 5lb3 ATP-DEPENDENT DNA
HELICASE Q5
(Homo
sapiens) 		5 / 10 VAL B 203
ASP B 202
LEU B 191
THR B  54
GLN B 345
 None
None
None
ADP  B 502 (-4.1A)
None
 1.50A 3j6gH-5lb3B:
0.4		 3j6gH-5lb3B:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_J_TA1J502_1
(TUBULIN BETA CHAIN)		 5lb3 ATP-DEPENDENT DNA
HELICASE Q5
(Homo
sapiens) 		5 / 10 VAL B 203
ASP B 202
LEU B 191
THR B  54
GLN B 345
 None
None
None
ADP  B 502 (-4.1A)
None
 1.50A 3j6gJ-5lb3B:
1.9		 3j6gJ-5lb3B:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_L_TA1L502_1
(TUBULIN BETA CHAIN)		 5lb3 ATP-DEPENDENT DNA
HELICASE Q5
(Homo
sapiens) 		5 / 10 VAL B 203
ASP B 202
LEU B 191
THR B  54
GLN B 345
 None
None
None
ADP  B 502 (-4.1A)
None
 1.50A 3j6gL-5lb3B:
2.0		 3j6gL-5lb3B:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_N_TA1N502_1
(TUBULIN BETA CHAIN)		 5lb3 ATP-DEPENDENT DNA
HELICASE Q5
(Homo
sapiens) 		5 / 10 VAL B 203
ASP B 202
LEU B 191
THR B  54
GLN B 345
 None
None
None
ADP  B 502 (-4.1A)
None
 1.49A 3j6gN-5lb3B:
undetectable		 3j6gN-5lb3B:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_P_TA1P502_1
(TUBULIN BETA CHAIN)		 5lb3 ATP-DEPENDENT DNA
HELICASE Q5
(Homo
sapiens) 		5 / 10 VAL B 203
ASP B 202
LEU B 191
THR B  54
GLN B 345
 None
None
None
ADP  B 502 (-4.1A)
None
 1.50A 3j6gP-5lb3B:
2.0		 3j6gP-5lb3B:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_R_TA1R502_1
(TUBULIN BETA CHAIN)		 5lb3 ATP-DEPENDENT DNA
HELICASE Q5
(Homo
sapiens) 		5 / 10 VAL B 203
ASP B 202
LEU B 191
THR B  54
GLN B 345
 None
None
None
ADP  B 502 (-4.1A)
None
 1.50A 3j6gR-5lb3B:
1.7		 3j6gR-5lb3B:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_A_MIYA2001_1
(TETX2 PROTEIN)		 5lb3 ATP-DEPENDENT DNA
HELICASE Q5
(Homo
sapiens) 		5 / 11 ARG B 222
HIS B 413
PRO B 356
GLY B 354
ASN B 327
 None
 1.47A 3v3nA-5lb3B:
undetectable		 3v3nA-5lb3B:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZWI_A_ASCA156_0
(CYTOCHROME C')		 5lb3 ATP-DEPENDENT DNA
HELICASE Q5
(Homo
sapiens) 		4 / 5 ALA B 414
GLY B 430
CYH B 431
HIS B 433
 None
None
ZN  B 501 (-2.4A)
None
 1.42A 3zwiA-5lb3B:
undetectable		 3zwiA-5lb3B:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_C_RTLC201_0
(RETINOL-BINDING
PROTEIN 2)		 5lb3 ATP-DEPENDENT DNA
HELICASE Q5
(Homo
sapiens) 		5 / 12 PHE B 138
ILE B  74
ALA B 133
LEU B 126
LEU B 113
 None
 1.41A 4qztC-5lb3B:
undetectable		 4qztC-5lb3B:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_B_CHDB102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5lb3 ATP-DEPENDENT DNA
HELICASE Q5
(Homo
sapiens) 		5 / 11 LEU B 126
LEU B 100
GLU B 111
ALA B 114
LEU B 113
 None
 1.05A 4wg0B-5lb3B:
undetectable
4wg0C-5lb3B:
undetectable
4wg0D-5lb3B:
undetectable		 4wg0B-5lb3B:
5.06
4wg0C-5lb3B:
5.06
4wg0D-5lb3B:
5.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_C_CHDC102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5lb3 ATP-DEPENDENT DNA
HELICASE Q5
(Homo
sapiens) 		5 / 7 GLU B 111
LEU B 112
ASN B 101
LEU B 100
LEU B 126
 None
 1.31A 4wg0B-5lb3B:
undetectable
4wg0C-5lb3B:
undetectable		 4wg0B-5lb3B:
5.06
4wg0C-5lb3B:
5.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_D_CHDD102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5lb3 ATP-DEPENDENT DNA
HELICASE Q5
(Homo
sapiens) 		5 / 11 LEU B 126
LEU B 100
GLU B 111
ALA B 114
LEU B 113
 None
 1.04A 4wg0D-5lb3B:
undetectable
4wg0E-5lb3B:
undetectable
4wg0F-5lb3B:
undetectable		 4wg0D-5lb3B:
5.06
4wg0E-5lb3B:
5.06
4wg0F-5lb3B:
5.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADG_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5lb3 ATP-DEPENDENT DNA
HELICASE Q5
(Homo
sapiens) 		4 / 7 GLU B 307
MET B 306
VAL B 310
TRP B 305
 None
 1.38A 5adgA-5lb3B:
undetectable
5adgB-5lb3B:
undetectable		 5adgA-5lb3B:
21.06
5adgB-5lb3B:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADI_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5lb3 ATP-DEPENDENT DNA
HELICASE Q5
(Homo
sapiens) 		4 / 7 MET B 306
VAL B 310
TRP B 305
GLU B 307
 None
 1.39A 5adiA-5lb3B:
undetectable
5adiB-5lb3B:
undetectable		 5adiA-5lb3B:
21.06
5adiB-5lb3B:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLI_A_ASCA202_0
(CYTOCHROME C')		 5lb3 ATP-DEPENDENT DNA
HELICASE Q5
(Homo
sapiens) 		4 / 5 ALA B 414
GLY B 430
CYH B 431
HIS B 433
 None
None
ZN  B 501 (-2.4A)
None
 1.41A 5jliA-5lb3B:
undetectable		 5jliA-5lb3B:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JT4_A_ASCA202_0
(CYTOCHROME C')		 5lb3 ATP-DEPENDENT DNA
HELICASE Q5
(Homo
sapiens) 		4 / 5 ALA B 414
GLY B 430
CYH B 431
HIS B 433
 None
None
ZN  B 501 (-2.4A)
None
 1.43A 5jt4A-5lb3B:
undetectable		 5jt4A-5lb3B:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND3_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 5lb3 ATP-DEPENDENT DNA
HELICASE Q5
(Homo
sapiens) 		5 / 12 VAL B 203
ASP B 202
LEU B 191
ALA B 159
THR B  54
 None
None
None
None
ADP  B 502 (-4.1A)
 1.24A 5nd3B-5lb3B:
undetectable		 5nd3B-5lb3B:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5lb3 ATP-DEPENDENT DNA
HELICASE Q5
(Homo
sapiens) 		4 / 7 GLU B 307
MET B 306
VAL B 310
TRP B 305
 None
 1.36A 5unuA-5lb3B:
undetectable
5unuB-5lb3B:
undetectable		 5unuA-5lb3B:
21.47
5unuB-5lb3B:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5lb3 ATP-DEPENDENT DNA
HELICASE Q5
(Homo
sapiens) 		4 / 7 GLU B 307
MET B 306
VAL B 310
TRP B 305
 None
 1.35A 5uo1A-5lb3B:
undetectable
5uo1B-5lb3B:
undetectable		 5uo1A-5lb3B:
21.06
5uo1B-5lb3B:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5lb3 ATP-DEPENDENT DNA
HELICASE Q5
(Homo
sapiens) 		4 / 7 MET B 306
VAL B 310
TRP B 305
GLU B 307
 None
 1.37A 5uo3A-5lb3B:
undetectable
5uo3B-5lb3B:
undetectable		 5uo3A-5lb3B:
21.06
5uo3B-5lb3B:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO5_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5lb3 ATP-DEPENDENT DNA
HELICASE Q5
(Homo
sapiens) 		4 / 7 GLU B 307
MET B 306
VAL B 310
TRP B 305
 None
 1.42A 5uo5A-5lb3B:
undetectable
5uo5B-5lb3B:
undetectable		 5uo5A-5lb3B:
21.06
5uo5B-5lb3B:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO6_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5lb3 ATP-DEPENDENT DNA
HELICASE Q5
(Homo
sapiens) 		4 / 7 GLU B 307
MET B 306
VAL B 310
TRP B 305
 None
 1.40A 5uo6A-5lb3B:
undetectable
5uo6B-5lb3B:
undetectable		 5uo6A-5lb3B:
21.06
5uo6B-5lb3B:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO7_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5lb3 ATP-DEPENDENT DNA
HELICASE Q5
(Homo
sapiens) 		4 / 7 GLU B 307
MET B 306
VAL B 310
TRP B 305
 None
 1.42A 5uo7A-5lb3B:
undetectable
5uo7B-5lb3B:
undetectable		 5uo7A-5lb3B:
21.06
5uo7B-5lb3B:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5lb3 ATP-DEPENDENT DNA
HELICASE Q5
(Homo
sapiens) 		4 / 7 GLU B 307
MET B 306
VAL B 310
TRP B 305
 None
 1.34A 5vuiA-5lb3B:
undetectable
5vuiB-5lb3B:
undetectable		 5vuiA-5lb3B:
21.47
5vuiB-5lb3B:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5lb3 ATP-DEPENDENT DNA
HELICASE Q5
(Homo
sapiens) 		4 / 7 GLU B 307
MET B 306
VAL B 310
TRP B 305
 None
 1.38A 5vuvA-5lb3B:
undetectable
5vuvB-5lb3B:
undetectable		 5vuvA-5lb3B:
21.06
5vuvB-5lb3B:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA503_1
(CYTOCHROME P450 2C9)		 5lb3 ATP-DEPENDENT DNA
HELICASE Q5
(Homo
sapiens) 		5 / 12 LEU B 154
PRO B 140
THR B 141
LEU B 116
PHE B 138
 None
 1.19A 5xxiA-5lb3B:
undetectable		 5xxiA-5lb3B:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5lb3 ATP-DEPENDENT DNA
HELICASE Q5
(Homo
sapiens) 		4 / 7 GLU B 307
MET B 306
VAL B 310
TRP B 305
 None
 1.39A 6auuA-5lb3B:
undetectable
6auuB-5lb3B:
undetectable		 6auuA-5lb3B:
10.56
6auuB-5lb3B:
10.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_B_ACTB804_0
(UNCHARACTERIZED
PROTEIN)		 5lb3 ATP-DEPENDENT DNA
HELICASE Q5
(Homo
sapiens) 		4 / 4 HIS B 290
VAL B 301
LEU B 293
ALA B 288
 None
 1.09A 6d8pB-5lb3B:
2.8		 6d8pB-5lb3B:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_C_AM2C301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 5lb3 ATP-DEPENDENT DNA
HELICASE Q5
(Homo
sapiens) 		4 / 8 ARG B 148
HIS B 149
GLU B 119
GLU B 117
 None
 1.27A 6mn4C-5lb3B:
undetectable		 6mn4C-5lb3B:
21.43