SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5lb7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_1
(VITAMIN D NUCLEAR
RECEPTOR)		 5lb7 KATANIN P80 WD40
REPEAT-CONTAINING
SUBUNIT B1
(Mus
musculus) 		5 / 12 LEU A 570
LEU A 632
VAL A 633
SER A 635
VAL A 578
 None
 1.32A 1db1A-5lb7A:
undetectable		 1db1A-5lb7A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE9_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 5lb7 KATANIN P80 WD40
REPEAT-CONTAINING
SUBUNIT B1
(Mus
musculus) 		5 / 12 LEU A 570
LEU A 632
VAL A 633
SER A 635
VAL A 578
 None
 1.33A 1ie9A-5lb7A:
undetectable		 1ie9A-5lb7A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_B_BEZB301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)		 5lb7 KATANIN P80 WD40
REPEAT-CONTAINING
SUBUNIT B1
(Mus
musculus) 		4 / 8 ILE A 588
LEU A 589
MET A 654
LEU A 653
 None
 0.91A 5u4sB-5lb7A:
undetectable		 5u4sB-5lb7A:
21.80