SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5lbk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PWY_E_AC2E290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
5lbk COPPER-TRANSPORTING
ATPASE PAA2,
CHLOROPLASTIC

(Arabidopsis
thaliana)
5 / 10 VAL A 628
GLY A 629
THR A 611
VAL A 580
HIS A 586
None
1.05A 1pwyE-5lbkA:
undetectable
1pwyE-5lbkA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R5L_A_VIVA301_0
(PROTEIN
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN))
5lbk COPPER-TRANSPORTING
ATPASE PAA2,
CHLOROPLASTIC

(Arabidopsis
thaliana)
5 / 12 ILE A 687
ILE A 685
VAL A 573
VAL A 626
ILE A 592
None
1.29A 1r5lA-5lbkA:
undetectable
1r5lA-5lbkA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)
5lbk COPPER-TRANSPORTING
ATPASE PAA2,
CHLOROPLASTIC

(Arabidopsis
thaliana)
4 / 6 ARG A 676
ILE A 682
GLY A 675
ALA A 627
None
0.89A 1wmqA-5lbkA:
undetectable
1wmqA-5lbkA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)
5lbk COPPER-TRANSPORTING
ATPASE PAA2,
CHLOROPLASTIC

(Arabidopsis
thaliana)
4 / 6 ARG A 676
ILE A 682
GLY A 675
ALA A 627
None
0.88A 1wmqB-5lbkA:
undetectable
1wmqB-5lbkA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)
5lbk COPPER-TRANSPORTING
ATPASE PAA2,
CHLOROPLASTIC

(Arabidopsis
thaliana)
4 / 6 ARG A 676
ILE A 682
GLY A 675
ALA A 627
None
0.89A 1wpuA-5lbkA:
undetectable
1wpuA-5lbkA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)
5lbk COPPER-TRANSPORTING
ATPASE PAA2,
CHLOROPLASTIC

(Arabidopsis
thaliana)
4 / 6 ARG A 676
ILE A 682
GLY A 675
ALA A 627
None
0.88A 1wpuB-5lbkA:
undetectable
1wpuB-5lbkA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)
5lbk COPPER-TRANSPORTING
ATPASE PAA2,
CHLOROPLASTIC

(Arabidopsis
thaliana)
4 / 6 ARG A 676
ILE A 682
GLY A 675
ALA A 627
None
0.88A 1wrqA-5lbkA:
undetectable
1wrqA-5lbkA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)
5lbk COPPER-TRANSPORTING
ATPASE PAA2,
CHLOROPLASTIC

(Arabidopsis
thaliana)
4 / 6 ARG A 676
ILE A 682
GLY A 675
ALA A 627
None
0.88A 1wrqB-5lbkA:
undetectable
1wrqB-5lbkA:
22.02