SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5lbs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OA1_B_ADNB2005_1
(TRYPTOPHAN
HALOGENASE)		 5lbs BROADLY NEUTRALIZING
HUMAN ANTIBODY EDE1
C8
(Homo
sapiens) 		4 / 7 GLY H  94
GLY H  95
ARG H  71
LEU H  78
 None
EDO  H 202 ( 3.7A)
None
None
 0.65A 2oa1B-5lbsH:
undetectable		 2oa1B-5lbsH:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PO7_A_ZONA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 5lbs BROADLY NEUTRALIZING
HUMAN ANTIBODY EDE1
C8
(Homo
sapiens) 		4 / 8 TYR H  59
LEU H  78
PHE H  80
TYR H  47
 None
 1.31A 3po7A-5lbsH:
undetectable		 3po7A-5lbsH:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_3
(NS3 PROTEASE, NS4A
PROTEIN)		 5lbs BROADLY NEUTRALIZING
HUMAN ANTIBODY EDE1
C8
(Homo
sapiens) 		4 / 5 SER H  82
ARG H  83
PRO H  84
VAL H 111
 None
 1.11A 3sufC-5lbsH:
undetectable		 3sufC-5lbsH:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5lbs BROADLY NEUTRALIZING
HUMAN ANTIBODY EDE1
C8
(Homo
sapiens) 		4 / 7 ALA H  88
THR H  87
VAL H 109
GLU H  85
 None
 0.71A 5ecmD-5lbsH:
undetectable		 5ecmD-5lbsH:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5lbs BROADLY NEUTRALIZING
HUMAN ANTIBODY EDE1
C8
(Homo
sapiens) 		4 / 7 ALA H  88
THR H  87
VAL H 109
GLU H  85
 None
 0.78A 5ecoD-5lbsH:
undetectable		 5ecoD-5lbsH:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BTX_A_EDTA503_0
(SOLUTE CARRIER
FAMILY 39
(IRON-REGULATED
TRANSPORTER))		 5lbs BROADLY NEUTRALIZING
HUMAN ANTIBODY EDE1
C8
(Homo
sapiens) 		4 / 7 SER H  97
SER H  33
HIS H  35
GLY H  94
 None
 0.84A 6btxA-5lbsH:
undetectable		 6btxA-5lbsH:
16.51