SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5lcl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZEA_A_DHIA6_0
(MONOCLONAL
ANTI-CHOLERA TOXIN
IGG1 KAPPA ANTIBODY,
H CHAIN
MONOCLONAL
ANTI-CHOLERA TOXIN
IGG1 KAPPA ANTIBODY,
L CHAIN
SHORT SYNTHETIC
D-AMINO ACID PEPTIDE
D2)		 5lcl DNA REPAIR PROTEIN
RAD14
(Saccharomyces
cerevisiae) 		3 / 3 TRP A 291
ARG A 294
PHE A 237
 None
 1.37A 1zeaH-5lclA:
undetectable
1zeaL-5lclA:
undetectable		 1zeaH-5lclA:
17.51
1zeaL-5lclA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZEA_A_DHIA6_0
(MONOCLONAL
ANTI-CHOLERA TOXIN
IGG1 KAPPA ANTIBODY,
H CHAIN
MONOCLONAL
ANTI-CHOLERA TOXIN
IGG1 KAPPA ANTIBODY,
L CHAIN
SHORT SYNTHETIC
D-AMINO ACID PEPTIDE
D2)		 5lcl DNA REPAIR PROTEIN
RAD14
(Saccharomyces
cerevisiae) 		3 / 3 TRP B 291
ARG B 294
PHE B 237
 None
 1.40A 1zeaH-5lclB:
undetectable
1zeaL-5lclB:
undetectable		 1zeaH-5lclB:
18.28
1zeaL-5lclB:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_H_HCZH800_1
(GLUTAMATE RECEPTOR 2)		 5lcl DNA REPAIR PROTEIN
RAD14
(Saccharomyces
cerevisiae) 		4 / 5 LYS A 254
PRO A 255
SER A 259
LEU A 267
 None
 1.44A 3ijxH-5lclA:
undetectable		 3ijxH-5lclA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_H_HCZH800_1
(GLUTAMATE RECEPTOR 2)		 5lcl DNA REPAIR PROTEIN
RAD14
(Saccharomyces
cerevisiae) 		4 / 5 LYS B 254
PRO B 255
SER B 259
LEU B 267
 None
 1.42A 3ijxH-5lclB:
undetectable		 3ijxH-5lclB:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_H_HFZH800_1
(GLUTAMATE RECEPTOR 2)		 5lcl DNA REPAIR PROTEIN
RAD14
(Saccharomyces
cerevisiae) 		4 / 5 LYS A 254
PRO A 255
SER A 259
LEU A 267
 None
 1.43A 3iluH-5lclA:
undetectable		 3iluH-5lclA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_H_HFZH800_1
(GLUTAMATE RECEPTOR 2)		 5lcl DNA REPAIR PROTEIN
RAD14
(Saccharomyces
cerevisiae) 		4 / 5 LYS B 254
PRO B 255
SER B 259
LEU B 267
 None
 1.41A 3iluH-5lclB:
undetectable		 3iluH-5lclB:
20.00