SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ldd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A8U_A_BEZA295_0
(CHLOROPEROXIDASE T)		 5ldd CCZ1
(Chaetomium
thermophilum) 		5 / 10 GLY B  18
PHE B  19
LEU B 239
THR B  46
LEU B  47
 None
 1.47A 1a8uA-5lddB:
undetectable		 1a8uA-5lddB:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A8U_B_BEZB294_0
(CHLOROPEROXIDASE T)		 5ldd CCZ1
(Chaetomium
thermophilum) 		5 / 10 GLY B  18
PHE B  19
LEU B 239
THR B  46
LEU B  47
 None
 1.48A 1a8uB-5lddB:
undetectable		 1a8uB-5lddB:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DF7_A_MTXA501_2
(DIHYDROFOLATE
REDUCTASE)		 5ldd CCZ1
(Chaetomium
thermophilum) 		3 / 3 TRP B 242
ARG B 233
THR B 241
 None
 0.85A 1df7A-5lddB:
undetectable		 1df7A-5lddB:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_A_CAMA502_0
(CYTOCHROME P450-CAM)		 5ldd MON1
CCZ1
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		4 / 6 PHE B 114
LEU A 226
VAL A 287
VAL A 274
 None
 1.01A 1dz4A-5lddB:
undetectable		 1dz4A-5lddB:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_B_CAMB502_0
(CYTOCHROME P450-CAM)		 5ldd MON1
CCZ1
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		4 / 6 PHE B 114
LEU A 226
VAL A 287
VAL A 274
 None
 1.00A 1dz4B-5lddB:
undetectable		 1dz4B-5lddB:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E71_M_ASCM995_0
(MYROSINASE MA1)		 5ldd RAB SMALL MONOMERIC
GTPASE-LIKE PROTEIN
(Chaetomium
thermophilum) 		4 / 7 ARG C  69
PHE C  70
PHE C  77
PHE C  45
 None
 1.25A 1e71M-5lddC:
undetectable		 1e71M-5lddC:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_B_CHDB1250_0
(ALCOHOL
DEHYDROGENASE)		 5ldd MON1
(Chaetomium
thermophilum) 		3 / 3 MET A 308
LEU A 311
SER A 312
 None
 0.36A 1ee2A-5lddA:
undetectable		 1ee2A-5lddA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T85_A_CAMA422_0
(CYTOCHROME P450-CAM)		 5ldd MON1
CCZ1
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		4 / 7 PHE B 114
LEU A 226
VAL A 287
VAL A 274
 None
 0.98A 1t85A-5lddB:
undetectable		 1t85A-5lddB:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 5ldd MON1
CCZ1
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		4 / 7 PHE B 114
LEU A 226
VAL A 287
VAL A 274
 None
 1.01A 1t87A-5lddB:
undetectable		 1t87A-5lddB:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 5ldd MON1
CCZ1
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		4 / 5 PHE B 114
LEU A 226
VAL A 287
VAL A 274
 None
 1.00A 1t88B-5lddB:
undetectable		 1t88B-5lddB:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_A_HSMA401_1
(NITROPHORIN 1)		 5ldd MON1
(Chaetomium
thermophilum) 		4 / 4 ASP A 296
LEU A 303
LEU A 279
LEU A 299
 None
 1.22A 1u18A-5lddA:
undetectable		 1u18A-5lddA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRC_A_CAMA420_0
(CYTOCHROME P450-CAM)		 5ldd MON1
CCZ1
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		4 / 7 PHE B 114
LEU A 226
VAL A 287
VAL A 274
 None
 0.97A 1yrcA-5lddB:
undetectable		 1yrcA-5lddB:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRD_A_CAMA420_0
(CYTOCHROME P450-CAM)		 5ldd MON1
CCZ1
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		4 / 7 PHE B 114
LEU A 226
VAL A 287
VAL A 274
 None
 0.99A 1yrdA-5lddB:
undetectable		 1yrdA-5lddB:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CPP_A_CAMA422_0
(CYTOCHROME P450-CAM)		 5ldd MON1
CCZ1
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		4 / 7 PHE B 114
LEU A 226
VAL A 287
VAL A 274
 None
 1.00A 2cppA-5lddB:
undetectable		 2cppA-5lddB:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 5ldd MON1
CCZ1
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		4 / 6 PHE B 114
LEU A 226
VAL A 287
VAL A 274
 None
 0.95A 2feuA-5lddB:
undetectable		 2feuA-5lddB:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_B_CAMB1421_0
(CYTOCHROME P450-CAM)		 5ldd MON1
CCZ1
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		4 / 7 PHE B 114
LEU A 226
VAL A 287
VAL A 274
 None
 0.95A 2feuB-5lddB:
undetectable		 2feuB-5lddB:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBL_A_CAMA517_0
(CYTOCHROME P450-CAM)		 5ldd MON1
CCZ1
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		4 / 7 PHE B 114
LEU A 226
VAL A 287
VAL A 274
 None
 0.98A 2qblA-5lddB:
undetectable		 2qblA-5lddB:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UVN_B_ECNB1406_1
(CYTOCHROME P450 130)		 5ldd CCZ1
(Chaetomium
thermophilum) 		5 / 11 ASP B 199
PRO B 192
PRO B 193
LEU B 246
VAL B 244
 None
 1.31A 2uvnB-5lddB:
undetectable		 2uvnB-5lddB:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAW_A_CAMA422_0
(CYTOCHROME P450-CAM)		 5ldd MON1
CCZ1
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		4 / 6 PHE B 114
LEU A 226
VAL A 287
VAL A 274
 None
 1.12A 2zawA-5lddB:
undetectable		 2zawA-5lddB:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAX_A_CAMA422_0
(CYTOCHROME P450-CAM)		 5ldd MON1
CCZ1
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		4 / 7 PHE B 114
LEU A 226
VAL A 287
VAL A 274
 None
 0.98A 2zaxA-5lddB:
undetectable		 2zaxA-5lddB:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUH_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 5ldd MON1
CCZ1
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		4 / 6 PHE B 114
LEU A 226
VAL A 287
VAL A 274
 None
 1.07A 2zuhA-5lddB:
undetectable		 2zuhA-5lddB:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUI_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 5ldd MON1
CCZ1
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		4 / 6 PHE B 114
LEU A 226
VAL A 287
VAL A 274
 None
 1.01A 2zuiA-5lddB:
undetectable		 2zuiA-5lddB:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWT_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 5ldd MON1
CCZ1
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		4 / 7 PHE B 114
LEU A 226
VAL A 287
VAL A 274
 None
 0.99A 2zwtA-5lddB:
undetectable		 2zwtA-5lddB:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWU_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 5ldd MON1
CCZ1
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		4 / 7 PHE B 114
LEU A 226
VAL A 287
VAL A 274
 None
 0.99A 2zwuA-5lddB:
undetectable		 2zwuA-5lddB:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_1
(PROTEASE)		 5ldd RAB SMALL MONOMERIC
GTPASE-LIKE PROTEIN
(Chaetomium
thermophilum) 		4 / 8 GLY C  80
ALA C  81
ASP C  82
THR C  64
 None
 0.59A 3el0A-5lddC:
undetectable		 3el0A-5lddC:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 5ldd MON1
CCZ1
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		4 / 7 PHE B 114
LEU A 226
VAL A 287
VAL A 274
 None
 0.96A 3fwfA-5lddB:
undetectable		 3fwfA-5lddB:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 5ldd MON1
CCZ1
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		4 / 7 PHE B 114
LEU A 226
VAL A 287
VAL A 274
 None
 0.94A 3fwfB-5lddB:
undetectable		 3fwfB-5lddB:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 5ldd MON1
CCZ1
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		4 / 6 PHE B 114
LEU A 226
VAL A 287
VAL A 274
 None
 0.96A 3fwgA-5lddB:
undetectable		 3fwgA-5lddB:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 5ldd MON1
CCZ1
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		4 / 7 PHE B 114
LEU A 226
VAL A 287
VAL A 274
 None
 0.97A 3fwgB-5lddB:
undetectable		 3fwgB-5lddB:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWI_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 5ldd MON1
CCZ1
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		4 / 7 PHE B 114
LEU A 226
VAL A 287
VAL A 274
 None
 1.00A 3fwiA-5lddB:
undetectable		 3fwiA-5lddB:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWJ_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 5ldd MON1
CCZ1
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		4 / 7 PHE B 114
LEU A 226
VAL A 287
VAL A 274
 None
 0.96A 3fwjA-5lddB:
undetectable		 3fwjA-5lddB:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GN8_A_DEXA247_2
(GLUCOCORTICOID
RECEPTOR 2)		 5ldd CCZ1
MON1
(Chaetomium
thermophilum) 		3 / 3 MET B 111
MET A 249
PHE A 258
 None
 1.31A 3gn8A-5lddB:
undetectable		 3gn8A-5lddB:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L63_A_CAMA440_0
(CAMPHOR
5-MONOOXYGENASE)		 5ldd MON1
CCZ1
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		4 / 7 PHE B 114
LEU A 226
VAL A 287
VAL A 274
 None
 0.92A 3l63A-5lddB:
undetectable		 3l63A-5lddB:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VKX_A_T3A301_1
(PROLIFERATING CELL
NUCLEAR ANTIGEN)		 5ldd RAB SMALL MONOMERIC
GTPASE-LIKE PROTEIN
(Chaetomium
thermophilum) 		4 / 6 MET C  59
LEU C   9
GLN C 178
PRO C 119
 None
 1.31A 3vkxA-5lddC:
undetectable		 3vkxA-5lddC:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5ldd MON1
CCZ1
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		4 / 7 PHE B 114
LEU A 226
VAL A 287
VAL A 274
 None
 0.95A 3wrhA-5lddB:
undetectable		 3wrhA-5lddB:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 5ldd MON1
CCZ1
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		4 / 6 PHE B 114
LEU A 226
VAL A 287
VAL A 274
 None
 0.95A 3wrhE-5lddB:
undetectable		 3wrhE-5lddB:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5ldd MON1
CCZ1
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		4 / 7 PHE B 114
LEU A 226
VAL A 287
VAL A 274
 None
 0.97A 3wrjA-5lddB:
undetectable		 3wrjA-5lddB:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 5ldd MON1
CCZ1
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		4 / 6 PHE B 114
LEU A 226
VAL A 287
VAL A 274
 None
 0.97A 3wrjE-5lddB:
undetectable		 3wrjE-5lddB:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5ldd MON1
CCZ1
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		4 / 7 PHE B 114
LEU A 226
VAL A 287
VAL A 274
 None
 0.93A 3wrlA-5lddB:
undetectable		 3wrlA-5lddB:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 5ldd MON1
CCZ1
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		4 / 7 PHE B 114
LEU A 226
VAL A 287
VAL A 274
 None
 0.95A 3wrlE-5lddB:
undetectable		 3wrlE-5lddB:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5ldd MON1
CCZ1
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		4 / 7 PHE B 114
LEU A 226
VAL A 287
VAL A 274
 None
 0.94A 3wrmA-5lddB:
undetectable		 3wrmA-5lddB:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_F_CAMF503_0
(CAMPHOR
5-MONOOXYGENASE)		 5ldd MON1
CCZ1
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		4 / 7 PHE B 114
LEU A 226
VAL A 287
VAL A 274
 None
 0.99A 3wrmF-5lddB:
undetectable		 3wrmF-5lddB:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5ldd MON1
RAB SMALL MONOMERIC
GTPASE-LIKE PROTEIN
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		5 / 9 ILE C  41
GLY C  42
VAL A 252
THR A 254
GLY A 250
 None
 1.18A 4acaB-5lddC:
13.8
4acaC-5lddC:
13.2		 4acaB-5lddC:
21.86
4acaC-5lddC:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AT0_A_ACTA1490_0
(3-KETOSTEROID-DELTA4
-5ALPHA-DEHYDROGENAS
E)		 5ldd CCZ1
RAB SMALL MONOMERIC
GTPASE-LIKE PROTEIN
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		3 / 3 GLU B 113
TYR C  37
SER C  36
 None
 1.00A 4at0A-5lddB:
undetectable		 4at0A-5lddB:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E0F_A_RBFA301_2
(RIBOFLAVIN SYNTHASE
SUBUNIT ALPHA)		 5ldd RAB SMALL MONOMERIC
GTPASE-LIKE PROTEIN
(Chaetomium
thermophilum) 		3 / 3 LYS C 161
THR C 156
ILE C 127
 None
 0.81A 4e0fB-5lddC:
undetectable		 4e0fB-5lddC:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5ldd MON1
CCZ1
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		4 / 6 PHE B 114
LEU A 226
VAL A 287
VAL A 274
 None
 0.93A 4ek1A-5lddB:
undetectable		 4ek1A-5lddB:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5ldd MON1
CCZ1
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		4 / 6 PHE B 114
LEU A 226
VAL A 287
VAL A 274
 None
 0.94A 4g3rA-5lddB:
undetectable		 4g3rA-5lddB:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 5ldd MON1
CCZ1
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		4 / 6 PHE B 114
LEU A 226
VAL A 287
VAL A 274
 None
 0.98A 4g3rB-5lddB:
undetectable		 4g3rB-5lddB:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KHP_A_PARA1606_1
(16S RIBOSOMAL RNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 5ldd MON1
RAB SMALL MONOMERIC
GTPASE-LIKE PROTEIN
(Chaetomium
thermophilum) 		3 / 3 TYR A 285
ARG C  79
SER A 230
 None
 0.86A 4khpI-5lddA:
undetectable
4khpJ-5lddA:
undetectable		 4khpI-5lddA:
20.22
4khpJ-5lddA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KKY_X_CAMX503_0
(CAMPHOR
5-MONOOXYGENASE)		 5ldd MON1
CCZ1
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		4 / 6 PHE B 114
LEU A 226
VAL A 287
VAL A 274
 None
 0.99A 4kkyX-5lddB:
undetectable		 4kkyX-5lddB:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L49_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5ldd MON1
CCZ1
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		4 / 5 PHE B 114
LEU A 226
VAL A 287
VAL A 274
 None
 0.95A 4l49A-5lddB:
undetectable		 4l49A-5lddB:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5ldd MON1
CCZ1
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		4 / 6 PHE B 114
LEU A 226
VAL A 287
VAL A 274
 None
 0.91A 4l4cA-5lddB:
undetectable		 4l4cA-5lddB:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5ldd MON1
CCZ1
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		4 / 7 PHE B 114
LEU A 226
VAL A 287
VAL A 274
 None
 0.99A 4l4gA-5lddB:
undetectable		 4l4gA-5lddB:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_2
(ADENOSINE KINASE)		 5ldd CCZ1
(Chaetomium
thermophilum) 		4 / 4 LEU B 227
SER B 216
LEU B  27
LEU B 231
 None
 1.00A 4n09A-5lddB:
undetectable		 4n09A-5lddB:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGV_A_ZITA404_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 5ldd CCZ1
MON1
(Chaetomium
thermophilum) 		4 / 4 ASN A 204
ILE A 227
TYR A 225
PHE B 118
 None
 1.22A 5igvA-5lddA:
undetectable		 5igvA-5lddA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5ldd MON1
(Chaetomium
thermophilum) 		3 / 3 ARG A 275
ILE A 289
PHE A 276
 None
 0.50A 5kirA-5lddA:
undetectable		 5kirA-5lddA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_A_SALA301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 5ldd RAB SMALL MONOMERIC
GTPASE-LIKE PROTEIN
(Chaetomium
thermophilum) 		4 / 5 ALA C  81
VAL C  11
PHE C 106
ILE C 171
 None
 0.99A 5of1A-5lddC:
undetectable		 5of1A-5lddC:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_B_SALB301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 5ldd RAB SMALL MONOMERIC
GTPASE-LIKE PROTEIN
(Chaetomium
thermophilum) 		4 / 5 ALA C  81
VAL C  11
PHE C 106
ILE C 171
 None
 0.97A 5of1B-5lddC:
undetectable		 5of1B-5lddC:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_1
(REGULATORY PROTEIN
TETR)		 5ldd CCZ1
(Chaetomium
thermophilum) 		4 / 7 GLY B 121
TRP B 144
GLN B 109
TYR B  23
 None
 1.20A 5vlmG-5lddB:
undetectable		 5vlmG-5lddB:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WK9_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5ldd MON1
CCZ1
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		4 / 7 PHE B 114
LEU A 226
VAL A 287
VAL A 274
 None
 0.92A 5wk9A-5lddB:
undetectable		 5wk9A-5lddB:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CHG_C_SAMC1101_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-4 SPECIFIC)		 5ldd CCZ1
(Chaetomium
thermophilum) 		5 / 12 ILE B  22
ASN B  24
SER B 216
SER B 217
LEU B 208
 None
 1.24A 6chgC-5lddB:
undetectable		 6chgC-5lddB:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CLX_B_SAMB401_0
(O-METHYLTRANSFERASE)		 5ldd MON1
CCZ1
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		5 / 10 ALA B 115
GLY A 272
ASP B 125
SER B 194
VAL A 274
 None
 1.46A 6clxB-5lddB:
undetectable		 6clxB-5lddB:
23.58