SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5lde'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZJ0_A_2FAA500_2 (ADENOSYLHOMOCYSTEINA SE)	5lde	IMMUNOGLOBULIN G-BINDING PROTEIN G,VIRAL FLICE PROTEIN (Human gammaherpesvirus 8; Streptococcus sp. 'group G')	4 / 5	THR A 152 THR A 187 HIS A 183 LEU A 180	None	1.34A	2zj0A-5ldeA: undetectable	2zj0A-5ldeA: 20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CE6_A_ADNA500_2 (ADENOSYLHOMOCYSTEINA SE)	5lde	IMMUNOGLOBULIN G-BINDING PROTEIN G,VIRAL FLICE PROTEIN (Human gammaherpesvirus 8; Streptococcus sp. 'group G')	4 / 5	THR A 152 THR A 187 HIS A 183 LEU A 180	None	1.38A	3ce6A-5ldeA: undetectable	3ce6A-5ldeA: 20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CE6_C_ADNC500_2 (ADENOSYLHOMOCYSTEINA SE)	5lde	IMMUNOGLOBULIN G-BINDING PROTEIN G,VIRAL FLICE PROTEIN (Human gammaherpesvirus 8; Streptococcus sp. 'group G')	4 / 5	THR A 152 THR A 187 HIS A 183 LEU A 180	None	1.36A	3ce6C-5ldeA: undetectable	3ce6C-5ldeA: 20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UNI_B_SALB1345_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	5lde	IMMUNOGLOBULIN G-BINDING PROTEIN G,VIRAL FLICE PROTEIN (Human gammaherpesvirus 8; Streptococcus sp. 'group G')	4 / 8	LEU A 107 VAL A 122 LEU A 126 ALA A 141	None	0.82A	3uniB-5ldeA: undetectable	3uniB-5ldeA: 11.11

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2ZJ0_A_2FAA500_2","ADENOSYLHOMOCYSTEINASE","5lde","IMMUNOGLOBULIN G-BINDING PROTEIN G,VIRAL FLICE PROTEIN","Human gammaherpesvirus 8;Streptococcus sp. 'group G'",4,"THR A 152;THR A 187;HIS A 183;LEU A 180","None","1.34A","2zj0A-5ldeA:undetectable","2zj0A-5ldeA:20.32"],["3CE6_A_ADNA500_2","ADENOSYLHOMOCYSTEINASE","5lde","IMMUNOGLOBULIN G-BINDING PROTEIN G,VIRAL FLICE PROTEIN","Human gammaherpesvirus 8;Streptococcus sp. 'group G'",4,"THR A 152;THR A 187;HIS A 183;LEU A 180","None","1.38A","3ce6A-5ldeA:undetectable","3ce6A-5ldeA:20.16"],["3CE6_C_ADNC500_2","ADENOSYLHOMOCYSTEINASE","5lde","IMMUNOGLOBULIN G-BINDING PROTEIN G,VIRAL FLICE PROTEIN","Human gammaherpesvirus 8;Streptococcus sp. 'group G'",4,"THR A 152;THR A 187;HIS A 183;LEU A 180","None","1.36A","3ce6C-5ldeA:undetectable","3ce6C-5ldeA:20.16"],["3UNI_B_SALB1345_1","XANTHINE DEHYDROGENASE\/OXIDASE","5lde","IMMUNOGLOBULIN G-BINDING PROTEIN G,VIRAL FLICE PROTEIN","Human gammaherpesvirus 8;Streptococcus sp. 'group G'",4,"LEU A 107;VAL A 122;LEU A 126;ALA A 141","None","0.82A","3uniB-5ldeA:undetectable","3uniB-5ldeA:11.11"]]