SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ldk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZWP_A_NIMA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 5ldk RNA 2',3'-CYCLIC
PHOSPHODIESTERASE
(Escherichia
coli) 		4 / 5 LEU A 128
GLY A  80
TRP A  82
ASP A  78
 None
 1.50A 1zwpA-5ldkA:
undetectable		 1zwpA-5ldkA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 5ldk RNA 2',3'-CYCLIC
PHOSPHODIESTERASE
(Escherichia
coli) 		5 / 9 LEU A  46
LEU A 106
ILE A  67
PHE A 152
LEU A 174
 None
 1.19A 2f78A-5ldkA:
undetectable		 2f78A-5ldkA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 5ldk RNA 2',3'-CYCLIC
PHOSPHODIESTERASE
(Escherichia
coli) 		5 / 9 LEU A  46
LEU A 106
ILE A  67
PHE A 152
LEU A 174
 None
 1.23A 2f78B-5ldkA:
undetectable		 2f78B-5ldkA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7A_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 5ldk RNA 2',3'-CYCLIC
PHOSPHODIESTERASE
(Escherichia
coli) 		5 / 9 LEU A  46
LEU A 106
ILE A  67
PHE A 152
LEU A 174
 None
 1.23A 2f7aB-5ldkA:
undetectable		 2f7aB-5ldkA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 5ldk RNA 2',3'-CYCLIC
PHOSPHODIESTERASE
(Escherichia
coli) 		5 / 9 PHE A  72
ALA A 173
LEU A 174
GLY A  71
ALA A 110
 None
 1.41A 4l6va-5ldkA:
undetectable
4l6vf-5ldkA:
undetectable		 4l6va-5ldkA:
13.05
4l6vf-5ldkA:
20.00