SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ldn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC2_0
(ACTINOMYCIN D)		 5ldn ANTIBODY
(Mus
musculus) 		4 / 4 THR H 120
PRO H 150
THR H 119
PRO H 121
 None
 1.30A 1dsdC-5ldnH:
undetectable		 1dsdC-5ldnH:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC8_0
(ACTINOMYCIN D)		 5ldn ANTIBODY
(Mus
musculus) 		4 / 4 THR H 120
PRO H 150
THR H 119
PRO H 121
 None
 1.30A 1dsdC-5ldnH:
undetectable		 1dsdC-5ldnH:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_C_MK1C402_1
(HIV-II PROTEASE)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		5 / 12 GLY A 220
ALA A 171
ILE A 215
GLY A 206
ILE A 205
 None
 0.93A 1hshC-5ldnA:
undetectable		 1hshC-5ldnA:
9.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_A_BEZA349_0
(D-AMINO ACID OXIDASE)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		4 / 5 TYR A 286
ILE A 185
ARG A 221
GLY A 220
 None
 1.22A 1kifA-5ldnA:
undetectable		 1kifA-5ldnA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_B_BEZB349_0
(D-AMINO ACID OXIDASE)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		4 / 5 TYR A 286
ILE A 185
ARG A 221
GLY A 220
 None
 1.21A 1kifB-5ldnA:
undetectable		 1kifB-5ldnA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_C_BEZC349_0
(D-AMINO ACID OXIDASE)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		4 / 5 TYR A 286
ILE A 185
ARG A 221
GLY A 220
 None
 1.22A 1kifC-5ldnA:
undetectable		 1kifC-5ldnA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_D_BEZD349_0
(D-AMINO ACID OXIDASE)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		4 / 5 TYR A 286
ILE A 185
ARG A 221
GLY A 220
 None
 1.21A 1kifD-5ldnA:
undetectable		 1kifD-5ldnA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_E_BEZE349_0
(D-AMINO ACID OXIDASE)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		4 / 5 TYR A 286
ILE A 185
ARG A 221
GLY A 220
 None
 1.22A 1kifE-5ldnA:
undetectable		 1kifE-5ldnA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_F_BEZF349_0
(D-AMINO ACID OXIDASE)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		4 / 5 TYR A 286
ILE A 185
ARG A 221
GLY A 220
 None
 1.22A 1kifF-5ldnA:
undetectable		 1kifF-5ldnA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_G_BEZG349_0
(D-AMINO ACID OXIDASE)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		4 / 5 TYR A 286
ILE A 185
ARG A 221
GLY A 220
 None
 1.21A 1kifG-5ldnA:
undetectable		 1kifG-5ldnA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_H_BEZH349_0
(D-AMINO ACID OXIDASE)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		4 / 5 TYR A 286
ILE A 185
ARG A 221
GLY A 220
 None
 1.22A 1kifH-5ldnA:
undetectable		 1kifH-5ldnA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NHZ_A_486A800_1
(GLUCOCORTICOID
RECEPTOR)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		5 / 12 MET A 336
ASN A 583
LEU A 614
GLN A 563
LEU A 347
 None
 1.41A 1nhzA-5ldnA:
undetectable		 1nhzA-5ldnA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_E_NCAE507_0
(NAD-DEPENDENT
DEACETYLASE 2)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		4 / 7 LEU A 371
ASN A 331
ILE A 333
ASP A 330
 None
 0.96A 1yc2E-5ldnA:
undetectable		 1yc2E-5ldnA:
12.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B60_B_RITB100_1
(GAG-POL POLYPROTEIN)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		5 / 12 GLY A 220
ALA A 171
ILE A 215
GLY A 206
ILE A 205
 None
 0.82A 2b60A-5ldnA:
undetectable		 2b60A-5ldnA:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_A_H4BA1290_1
(PTERIDINE REDUCTASE
1)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		4 / 8 ARG A 675
SER A 880
LEU A 371
LEU A 646
 None
 0.92A 2bfpA-5ldnA:
undetectable		 2bfpA-5ldnA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_D_H4BD1290_1
(PTERIDINE REDUCTASE
1)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		4 / 8 ARG A 675
SER A 880
LEU A 371
LEU A 646
 None
 0.90A 2bfpD-5ldnA:
undetectable		 2bfpD-5ldnA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		3 / 3 LYS A 685
ASP A 603
ASN A 498
 None
 1.08A 2bm9A-5ldnA:
undetectable		 2bm9A-5ldnA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E5D_B_NCAB1502_0
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		4 / 7 ASP A 330
ARG A 379
ASP A 708
ARG A 867
 None
 1.25A 2e5dA-5ldnA:
undetectable
2e5dB-5ldnA:
undetectable		 2e5dA-5ldnA:
20.17
2e5dB-5ldnA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_F_TACF3888_1
(ELONGATION FACTOR
EF-TU)		 5ldn ANTIBODY
(Mus
musculus) 		5 / 7 THR H 120
SER H 205
PRO H 122
VAL H 153
LEU H 173
 None
 1.49A 2hdnE-5ldnH:
undetectable
2hdnF-5ldnH:
undetectable
2hdnH-5ldnH:
undetectable		 2hdnE-5ldnH:
9.64
2hdnF-5ldnH:
19.02
2hdnH-5ldnH:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_H_TACH4888_1
(ELONGATION FACTOR
EF-TU)		 5ldn ANTIBODY
(Mus
musculus) 		5 / 7 VAL H 153
LEU H 173
THR H 120
SER H 205
PRO H 122
 None
 1.49A 2hdnF-5ldnH:
undetectable
2hdnG-5ldnH:
undetectable
2hdnH-5ldnH:
undetectable		 2hdnF-5ldnH:
19.02
2hdnG-5ldnH:
9.64
2hdnH-5ldnH:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1100_1
(SERUM ALBUMIN)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		4 / 6 PHE A 618
TYR A 578
ARG A 932
GLY A  88
 None
 1.34A 2i30A-5ldnA:
undetectable		 2i30A-5ldnA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_B_SC2B1290_1
(FICOLIN-2)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		4 / 8 LEU A 592
SER A 606
LEU A 106
ASP A 107
 None
 1.07A 2j2pA-5ldnA:
undetectable
2j2pB-5ldnA:
undetectable		 2j2pA-5ldnA:
13.85
2j2pB-5ldnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_1
(PROTEASE RETROPEPSIN)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		5 / 12 GLY A 220
ALA A 171
ILE A 215
GLY A 206
ILE A 205
 None
 0.78A 2rkfA-5ldnA:
undetectable		 2rkfA-5ldnA:
8.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_2
(PROTEASE RETROPEPSIN)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		5 / 12 GLY A 220
ALA A 171
ILE A 215
GLY A 206
ILE A 205
 None
 0.79A 2rkgB-5ldnA:
undetectable		 2rkgB-5ldnA:
8.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y03_A_5FWA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5ldn ANTIBODY
(Mus
musculus) 		5 / 12 VAL H 166
VAL H 184
SER H 182
ASN H 199
ASN H 158
 None
 1.44A 2y03A-5ldnH:
undetectable		 2y03A-5ldnH:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_A_SALA1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		5 / 9 THR A 885
GLY A 888
TYR A 893
GLY A 676
PHE A 724
 None
 1.29A 2y7wA-5ldnA:
undetectable		 2y7wA-5ldnA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_A_PAUA248_0
(TYPE III
PANTOTHENATE KINASE)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		5 / 10 GLY A 709
ASP A 708
THR A 687
LEU A 682
THR A 680
 None
 1.28A 3bexA-5ldnA:
undetectable
3bexB-5ldnA:
undetectable		 3bexA-5ldnA:
14.08
3bexB-5ldnA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		5 / 11 GLY A 709
ASP A 708
THR A 687
LEU A 682
THR A 680
 None
 1.29A 3bexC-5ldnA:
undetectable
3bexD-5ldnA:
undetectable		 3bexC-5ldnA:
14.08
3bexD-5ldnA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		5 / 11 THR A 687
LEU A 682
THR A 680
GLY A 709
ASP A 708
 None
 1.29A 3bexE-5ldnA:
undetectable
3bexF-5ldnA:
undetectable		 3bexE-5ldnA:
14.08
3bexF-5ldnA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_A_PAUA248_0
(TYPE III
PANTOTHENATE KINASE)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		5 / 11 GLY A 709
ASP A 708
THR A 687
LEU A 682
THR A 680
 None
 1.28A 3bf1A-5ldnA:
undetectable
3bf1B-5ldnA:
undetectable		 3bf1A-5ldnA:
14.08
3bf1B-5ldnA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		5 / 11 GLY A 709
ASP A 708
THR A 687
LEU A 682
THR A 680
 None
 1.31A 3bf1C-5ldnA:
undetectable
3bf1D-5ldnA:
undetectable		 3bf1C-5ldnA:
14.08
3bf1D-5ldnA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		5 / 11 THR A 687
LEU A 682
THR A 680
GLY A 709
ASP A 708
 None
 1.28A 3bf1C-5ldnA:
undetectable
3bf1D-5ldnA:
undetectable		 3bf1C-5ldnA:
14.08
3bf1D-5ldnA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		5 / 11 GLY A 709
ASP A 708
THR A 687
LEU A 682
THR A 680
 None
 1.29A 3bf1E-5ldnA:
undetectable
3bf1F-5ldnA:
undetectable		 3bf1E-5ldnA:
14.08
3bf1F-5ldnA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		5 / 11 THR A 687
LEU A 682
THR A 680
GLY A 709
ASP A 708
 None
 1.30A 3bf1E-5ldnA:
undetectable
3bf1F-5ldnA:
undetectable		 3bf1E-5ldnA:
14.08
3bf1F-5ldnA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_A_SVRA508_1
(PHOSPHOLIPASE A2)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		4 / 5 VAL A 390
GLN A 593
ARG A 379
ARG A 329
 None
 1.32A 3bjwE-5ldnA:
undetectable		 3bjwE-5ldnA:
8.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR5_X_PNTX94_0
(PROTEIN S100-B)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		3 / 3 PHE A 793
CYH A 865
PHE A 863
 None
 1.05A 3cr5X-5ldnA:
undetectable		 3cr5X-5ldnA:
7.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EBZ_B_017B201_2
(PROTEASE)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		5 / 11 GLY A 220
ALA A 171
ILE A 215
GLY A 206
ILE A 205
 None
 0.81A 3ebzB-5ldnA:
undetectable		 3ebzB-5ldnA:
9.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_2
(ADENOSYLHOMOCYSTEINA
SE)		 5ldn ANTIBODY
(Mus
musculus) 		3 / 3 THR H 113
GLU H 151
HIS H 202
 None
 0.79A 3g1uB-5ldnH:
undetectable		 3g1uB-5ldnH:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU4_B_478B401_2
(PROTEASE)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		5 / 9 GLY A 220
ALA A 171
ILE A 215
GLY A 206
ILE A 205
 None
 0.84A 3nu4B-5ldnA:
undetectable		 3nu4B-5ldnA:
7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHN_A_ACTA108_0
(PROTEIN P-30)		 5ldn ANTIBODY
(Mus
musculus) 		3 / 3 THR H  80
SER H  18
ARG H  16
 None
 0.76A 3phnA-5ldnH:
undetectable		 3phnA-5ldnH:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S43_A_478A401_2
(PROTEASE)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		5 / 10 GLY A 220
ALA A 171
ILE A 215
GLY A 206
ILE A 205
 None
 0.80A 3s43B-5ldnA:
undetectable		 3s43B-5ldnA:
7.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S45_B_478B201_2
(PROTEASE)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		5 / 11 GLY A 220
ALA A 171
ILE A 215
GLY A 206
ILE A 205
 None
 0.87A 3s45B-5ldnA:
undetectable		 3s45B-5ldnA:
9.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_1
(PROTEASE)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		5 / 9 GLY A 220
ALA A 171
ILE A 215
GLY A 206
ILE A 205
 None
 0.78A 3s53A-5ldnA:
undetectable		 3s53A-5ldnA:
7.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_A_ROCA201_1
(PROTEASE)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		5 / 12 GLY A 220
ALA A 171
ILE A 215
GLY A 206
ILE A 205
 None
 0.80A 3s56A-5ldnA:
undetectable		 3s56A-5ldnA:
7.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_A_017A201_1
(PROTEASE)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		5 / 12 GLY A 220
ALA A 171
ILE A 215
GLY A 206
ILE A 205
 None
 0.82A 3ucbA-5ldnA:
undetectable		 3ucbA-5ldnA:
8.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_A_RKEA401_1
(PROTON-GATED ION
CHANNEL)		 5ldn ANTIBODY
(Mus
musculus) 		4 / 8 TYR H  92
ASP H  87
PHE H  62
LEU H  47
 None
 0.80A 4f8hA-5ldnH:
undetectable
4f8hB-5ldnH:
undetectable		 4f8hA-5ldnH:
20.19
4f8hB-5ldnH:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_B_RKEB401_1
(PROTON-GATED ION
CHANNEL)		 5ldn ANTIBODY
(Mus
musculus) 		4 / 8 TYR H  92
ASP H  87
PHE H  62
LEU H  47
 None
 0.82A 4f8hB-5ldnH:
undetectable
4f8hC-5ldnH:
undetectable		 4f8hB-5ldnH:
20.19
4f8hC-5ldnH:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_C_RKEC401_1
(PROTON-GATED ION
CHANNEL)		 5ldn ANTIBODY
(Mus
musculus) 		4 / 8 TYR H  92
ASP H  87
PHE H  62
LEU H  47
 None
 0.79A 4f8hC-5ldnH:
undetectable
4f8hD-5ldnH:
undetectable		 4f8hC-5ldnH:
20.19
4f8hD-5ldnH:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_D_RKED401_1
(PROTON-GATED ION
CHANNEL)		 5ldn ANTIBODY
(Mus
musculus) 		4 / 8 TYR H  92
ASP H  87
PHE H  62
LEU H  47
 None
 0.79A 4f8hD-5ldnH:
undetectable
4f8hE-5ldnH:
undetectable		 4f8hD-5ldnH:
20.19
4f8hE-5ldnH:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_E_RKEE401_1
(PROTON-GATED ION
CHANNEL)		 5ldn ANTIBODY
(Mus
musculus) 		4 / 8 PHE H  62
LEU H  47
TYR H  92
ASP H  87
 None
 0.80A 4f8hA-5ldnH:
undetectable
4f8hE-5ldnH:
undetectable		 4f8hA-5ldnH:
20.19
4f8hE-5ldnH:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOG_D_C2FD302_0
(THYMIDYLATE SYNTHASE)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		5 / 11 LYS A 564
ILE A 704
LEU A 600
GLY A 334
ALA A 327
 None
 1.30A 4fogD-5ldnA:
undetectable		 4fogD-5ldnA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		5 / 12 VAL A 561
ALA A  81
PHE A 609
LEU A 549
PHE A 557
 None
 1.42A 4iarA-5ldnA:
undetectable		 4iarA-5ldnA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NX6_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		4 / 4 ILE A 858
ASP A 807
ARG A 802
THR A 808
 None
 1.27A 4nx6A-5ldnA:
undetectable		 4nx6A-5ldnA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NX7_A_FOLA202_1
(DIHYDROFOLATE
REDUCTASE)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		4 / 4 ILE A 858
ASP A 807
ARG A 802
THR A 808
 None
 1.27A 4nx7A-5ldnA:
undetectable		 4nx7A-5ldnA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		5 / 12 LEU A 600
THR A 111
LEU A 596
GLY A 597
ILE A 326
 None
 1.17A 4o5fA-5ldnA:
undetectable
4o5fB-5ldnA:
undetectable		 4o5fA-5ldnA:
15.19
4o5fB-5ldnA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_A_NPSA602_1
(SERUM ALBUMIN)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		5 / 9 ARG A  32
ALA A  31
ALA A  33
SER A  24
LEU A  27
 None
 1.19A 4or0A-5ldnA:
undetectable		 4or0A-5ldnA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1Y_A_017A106_1
(ASPARTYL PROTEASE)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		5 / 10 GLY A 220
ALA A 171
ILE A 215
GLY A 206
ILE A 205
 None
 0.76A 4q1yA-5ldnA:
undetectable		 4q1yA-5ldnA:
7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		5 / 12 THR A 628
THR A 625
ALA A 626
ALA A 622
ASN A  90
 None
 1.37A 4u15A-5ldnA:
undetectable		 4u15A-5ldnA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		5 / 12 THR A 628
THR A 625
ALA A 626
ALA A 622
ASN A  90
 None
 1.42A 4u15B-5ldnA:
undetectable		 4u15B-5ldnA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3U_B_SVRB102_1
(CHROMOBOX PROTEIN
HOMOLOG 7)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		3 / 3 LYS A 126
ARG A 836
VAL A 828
 None
 0.92A 4x3uA-5ldnA:
undetectable
4x3uB-5ldnA:
undetectable		 4x3uA-5ldnA:
5.18
4x3uB-5ldnA:
5.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_2
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		4 / 5 PHE A 944
HIS A 898
LEU A 900
PRO A 943
 None
 1.34A 5csyB-5ldnA:
undetectable		 5csyB-5ldnA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_1
(PROTEASE)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		5 / 12 GLY A 220
ALA A 171
ILE A 215
GLY A 206
ILE A 205
 None
 0.79A 5e5jA-5ldnA:
undetectable		 5e5jA-5ldnA:
7.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS1_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		4 / 5 TYR A 369
LYS A 564
GLU A 366
TYR A 338
 None
 1.41A 5js1A-5ldnA:
undetectable		 5js1A-5ldnA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		4 / 4 LEU A 335
ARG A 545
ILE A 559
PHE A 328
 None
 0.92A 5kirB-5ldnA:
undetectable		 5kirB-5ldnA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_B_SAMB304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		5 / 10 LEU A 573
GLY A 349
GLY A 933
ILE A 568
ALA A 356
 None
 1.01A 5l0zB-5ldnA:
undetectable		 5l0zB-5ldnA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_A_PFLA510_1
(PROTON-GATED ION
CHANNEL)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		5 / 9 ALA A 567
ILE A 568
TYR A 939
ILE A 935
LEU A 347
 None
 0.98A 5mvmA-5ldnA:
undetectable
5mvmE-5ldnA:
undetectable		 5mvmA-5ldnA:
7.35
5mvmE-5ldnA:
7.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_E_PFLE409_1
(PROTON-GATED ION
CHANNEL)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		5 / 10 ILE A 935
LEU A 347
ALA A 567
ILE A 568
TYR A 939
 None
 1.00A 5mvmD-5ldnA:
undetectable
5mvmE-5ldnA:
undetectable		 5mvmD-5ldnA:
7.35
5mvmE-5ldnA:
7.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_O_DVAO7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		3 / 3 TYR A  99
SER A  97
TRP A 386
 None
 1.07A 5n8jA-5ldnA:
undetectable		 5n8jA-5ldnA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_P_DVAP5_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		3 / 3 TYR A  99
SER A  97
TRP A 386
 None
 1.07A 5n8jD-5ldnA:
undetectable		 5n8jD-5ldnA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8H_B_478B401_1
(PROTEASE)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		5 / 12 GLY A 220
ALA A 171
ILE A 215
GLY A 206
ILE A 205
 None
 0.86A 5t8hA-5ldnA:
undetectable		 5t8hA-5ldnA:
7.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		5 / 12 LEU A 915
PHE A 679
VAL A 917
ALA A 649
TRP A 671
 None
 1.01A 5tzoB-5ldnA:
undetectable		 5tzoB-5ldnA:
11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		4 / 8 TRP A 677
TRP A 730
THR A 885
ARG A 675
 None
 1.26A 5tzoB-5ldnA:
undetectable		 5tzoB-5ldnA:
11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		4 / 8 TRP A 677
TRP A 730
THR A 885
ARG A 675
 None
 1.29A 5tzoC-5ldnA:
undetectable		 5tzoC-5ldnA:
11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA310_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		3 / 3 GLU A 936
HIS A 928
ARG A 926
 None
 0.96A 5uunA-5ldnA:
undetectable		 5uunA-5ldnA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_E_ZOLE401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		4 / 4 LEU A 542
ASP A 391
ASP A 708
ARG A 545
 None
 1.37A 6g31E-5ldnA:
undetectable		 6g31E-5ldnA:
6.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_B_FK5B201_0
(PEPTIDYLPROLYL
ISOMERASE)		 5ldn HEXON PROTEIN,HEXON
CAPSID
(Human
mastadenovirus
C) 		5 / 12 ARG A  72
PHE A 584
VAL A 561
ILE A 559
ILE A  68
 None
 1.18A 6mkeB-5ldnA:
undetectable
6mkeC-5ldnA:
undetectable		 6mkeB-5ldnA:
6.48
6mkeC-5ldnA:
6.48