SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ldr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKP_A_NVPA999_1
(HIV-1 RT, A-CHAIN)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		5 / 11 PRO B 642
LEU B 655
VAL B 680
GLY B 682
LEU B 647
 None
 1.05A 1fkpA-5ldrB:
undetectable		 1fkpA-5ldrB:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_A_DVAA6_0
(GRAMICIDIN A)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		3 / 3 ALA B  91
VAL B  89
TRP B  83
 None
PEG  B 803 (-4.0A)
None
 0.93A 1grmA-5ldrB:
undetectable		 1grmA-5ldrB:
6.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_B_DVAB6_0
(GRAMICIDIN A)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		3 / 3 ALA B  91
VAL B  89
TRP B  83
 None
PEG  B 803 (-4.0A)
None
 0.93A 1grmB-5ldrB:
undetectable		 1grmB-5ldrB:
6.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		4 / 7 GLY B 390
THR B 445
THR B 406
ILE B 358
 None
 0.79A 1gtnC-5ldrB:
undetectable
1gtnD-5ldrB:
undetectable		 1gtnC-5ldrB:
8.96
1gtnD-5ldrB:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		4 / 6 GLY B 390
THR B 445
THR B 406
ILE B 358
 None
 0.82A 1gtnD-5ldrB:
undetectable
1gtnE-5ldrB:
undetectable		 1gtnD-5ldrB:
8.96
1gtnE-5ldrB:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		4 / 7 GLY B 390
THR B 445
THR B 406
ILE B 358
 None
 0.83A 1gtnJ-5ldrB:
undetectable
1gtnK-5ldrB:
undetectable		 1gtnJ-5ldrB:
8.96
1gtnK-5ldrB:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		5 / 11 GLY B 391
GLY B 360
ILE B 363
ASP B 368
THR B 406
 None
 1.02A 1jg3A-5ldrB:
undetectable		 1jg3A-5ldrB:
13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_B_ADNB550_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		5 / 11 GLY B 391
GLY B 360
ILE B 363
ASP B 368
THR B 406
 None
 1.03A 1jg3B-5ldrB:
undetectable		 1jg3B-5ldrB:
13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_A_DVAA6_0
(GRAMICIDIN B)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		3 / 3 ALA B  91
VAL B  82
TRP B  83
 None
 0.91A 1jo3A-5ldrB:
undetectable		 1jo3A-5ldrB:
2.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_B_DVAB6_0
(GRAMICIDIN B)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		3 / 3 ALA B  91
VAL B  82
TRP B  83
 None
 0.91A 1jo3B-5ldrB:
undetectable		 1jo3B-5ldrB:
2.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWC_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		5 / 11 PRO B 642
LEU B 655
VAL B 680
GLY B 682
LEU B 647
 None
 1.10A 1lwcA-5ldrB:
undetectable		 1lwcA-5ldrB:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PJ5_A_ACTA2145_0
(N,N-DIMETHYLGLYCINE
OXIDASE)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		4 / 5 ARG B 143
TYR B  96
TYR B 275
TYR B 142
 None
 1.45A 1pj5A-5ldrB:
0.0		 1pj5A-5ldrB:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_1
(DNA TOPOISOMERASE II)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		4 / 7 HIS B 478
ASN B 448
TYR B 447
LEU B 427
 None
 1.10A 1qzrA-5ldrB:
undetectable		 1qzrA-5ldrB:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		4 / 7 HIS B 509
TRP B 489
THR B 496
TYR B 135
 None
GAL  B 801 (-3.8A)
None
None
 1.49A 1v54A-5ldrB:
undetectable
1v54C-5ldrB:
undetectable		 1v54A-5ldrB:
20.51
1v54C-5ldrB:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		4 / 7 HIS B 509
TRP B 489
THR B 496
TYR B 135
 None
GAL  B 801 (-3.8A)
None
None
 1.47A 1v54N-5ldrB:
undetectable
1v54P-5ldrB:
undetectable		 1v54N-5ldrB:
20.51
1v54P-5ldrB:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOT_A_VDNA101_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		5 / 12 TYR B 135
MET B  77
ILE B 133
SER B  47
PHE B 129
 None
 1.36A 1xotA-5ldrB:
undetectable		 1xotA-5ldrB:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOT_B_VDNB102_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		5 / 12 TYR B 135
MET B  77
ILE B 133
SER B  47
PHE B 129
 None
 1.37A 1xotB-5ldrB:
undetectable		 1xotB-5ldrB:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		4 / 7 HIS B 509
TRP B 489
THR B 496
TYR B 135
 None
GAL  B 801 (-3.8A)
None
None
 1.47A 2dyrN-5ldrB:
undetectable
2dyrP-5ldrB:
undetectable		 2dyrN-5ldrB:
20.51
2dyrP-5ldrB:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		4 / 7 HIS B 509
TRP B 489
THR B 496
TYR B 135
 None
GAL  B 801 (-3.8A)
None
None
 1.48A 2eijN-5ldrB:
undetectable
2eijP-5ldrB:
undetectable		 2eijN-5ldrB:
20.51
2eijP-5ldrB:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		4 / 7 HIS B 509
TRP B 489
THR B 496
TYR B 135
 None
GAL  B 801 (-3.8A)
None
None
 1.48A 2eikN-5ldrB:
undetectable
2eikP-5ldrB:
undetectable		 2eikN-5ldrB:
20.51
2eikP-5ldrB:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		4 / 7 HIS B 509
TRP B 489
THR B 496
TYR B 135
 None
GAL  B 801 (-3.8A)
None
None
 1.47A 2eilN-5ldrB:
undetectable
2eilP-5ldrB:
undetectable		 2eilN-5ldrB:
20.51
2eilP-5ldrB:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F6D_A_ACRA996_1
(GLUCOAMYLASE GLU1)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		4 / 7 ARG B 704
HIS B  33
ASN B   8
ASP B 652
 None
 1.03A 2f6dA-5ldrB:
undetectable		 2f6dA-5ldrB:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I2Z_A_SALA1100_1
(SERUM ALBUMIN)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		4 / 5 LEU B 655
ILE B 714
ILE B 640
ALA B 641
 None
 0.67A 2i2zA-5ldrB:
undetectable		 2i2zA-5ldrB:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1200_1
(SERUM ALBUMIN)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		4 / 4 LEU B 655
ILE B 714
ILE B 640
ALA B 641
 None
 0.70A 2i30A-5ldrB:
undetectable		 2i30A-5ldrB:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KCE_A_D16A566_1
(THYMIDYLATE SYNTHASE)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		5 / 12 SER B 301
GLU B 446
GLY B 449
VAL B 511
ALA B 521
 None
GAL  B 801 (-2.3A)
None
None
None
 1.34A 2kceA-5ldrB:
undetectable		 2kceA-5ldrB:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDB_A_NPSA1591_1
(SERUM ALBUMIN)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		4 / 8 ILE B 676
HIS B 718
PHE B 721
LEU B 638
 None
 0.81A 2vdbA-5ldrB:
undetectable		 2vdbA-5ldrB:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CHDA1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		4 / 7 HIS B 509
TRP B 489
THR B 496
TYR B 135
 None
GAL  B 801 (-3.8A)
None
None
 1.47A 2y69A-5ldrB:
undetectable
2y69C-5ldrB:
undetectable		 2y69A-5ldrB:
20.51
2y69C-5ldrB:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZQ9_A_CLSA11_1
(BETA-LACTAMASE
TOHO-1)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		4 / 4 GLU B 402
ARG B 362
ASN B 369
ASP B 368
 None
 1.45A 2zq9A-5ldrB:
undetectable		 2zq9A-5ldrB:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		4 / 5 ILE B 411
TYR B 442
MET B 407
THR B 445
 PEG  B 805 (-4.4A)
None
None
None
 1.32A 3abkN-5ldrB:
undetectable
3abkW-5ldrB:
undetectable		 3abkN-5ldrB:
20.51
3abkW-5ldrB:
6.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		4 / 7 HIS B 509
TRP B 489
THR B 496
TYR B 135
 None
GAL  B 801 (-3.8A)
None
None
 1.49A 3ag2N-5ldrB:
undetectable
3ag2P-5ldrB:
undetectable		 3ag2N-5ldrB:
20.51
3ag2P-5ldrB:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		4 / 7 HIS B 509
TRP B 489
THR B 496
TYR B 135
 None
GAL  B 801 (-3.8A)
None
None
 1.48A 3ag4N-5ldrB:
undetectable
3ag4P-5ldrB:
undetectable		 3ag4N-5ldrB:
20.51
3ag4P-5ldrB:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BUF_A_AEGA394_0
(BETA-SECRETASE 1)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		4 / 5 ASP B 493
ILE B 288
ILE B 514
GLY B 510
 None
 0.97A 3bufA-5ldrB:
undetectable		 3bufA-5ldrB:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA200_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		4 / 5 PRO B 304
THR B 406
VAL B 392
GLY B 391
 None
 0.80A 3elzA-5ldrB:
undetectable		 3elzA-5ldrB:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		5 / 12 MET B 346
PRO B 325
GLY B 391
VAL B 404
ILE B 358
 None
 1.25A 3jb2A-5ldrB:
undetectable		 3jb2A-5ldrB:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OF4_B_ACTB313_0
(NITROREDUCTASE)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		3 / 3 ALA B 631
VAL B 630
GLN B 664
 None
 0.56A 3of4B-5ldrB:
undetectable		 3of4B-5ldrB:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		5 / 11 LEU B 554
ILE B 468
ILE B 557
PHE B 567
VAL B 565
 None
 1.14A 3w67A-5ldrB:
1.7		 3w67A-5ldrB:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_A_ACHA301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		4 / 7 THR B 300
TYR B 135
TYR B 303
ARG B 266
 None
 1.40A 3wipA-5ldrB:
undetectable
3wipB-5ldrB:
2.6		 3wipA-5ldrB:
15.17
3wipB-5ldrB:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_B_ACHB301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		4 / 8 THR B 300
TYR B 135
TYR B 303
ARG B 266
 None
 1.44A 3wipB-5ldrB:
2.6
3wipC-5ldrB:
undetectable		 3wipB-5ldrB:
15.17
3wipC-5ldrB:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_D_ACHD301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		4 / 8 THR B 300
TYR B 135
TYR B 303
ARG B 266
 None
 1.45A 3wipD-5ldrB:
undetectable
3wipE-5ldrB:
undetectable		 3wipD-5ldrB:
15.17
3wipE-5ldrB:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_F_ACHF301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		4 / 7 THR B 300
TYR B 135
TYR B 303
ARG B 266
 None
 1.41A 3wipF-5ldrB:
undetectable
3wipG-5ldrB:
undetectable		 3wipF-5ldrB:
15.17
3wipG-5ldrB:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_A_ZMRA601_2
(NEURAMINIDASE)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		3 / 3 ARG B 312
ARG B 279
ILE B 316
 None
 0.94A 4b7qA-5ldrB:
undetectable		 4b7qA-5ldrB:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_C_ZMRC601_2
(NEURAMINIDASE)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		3 / 3 ARG B 312
ARG B 279
ILE B 316
 None
 0.74A 4b7qC-5ldrB:
undetectable		 4b7qC-5ldrB:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_B_ACTB1114_0
(BLR5658 PROTEIN)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		3 / 3 TRP B 146
TRP B 308
THR B 307
 None
 1.26A 4bboB-5ldrB:
undetectable		 4bboB-5ldrB:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		4 / 5 PRO B 555
ASP B 594
ILE B 557
VAL B 565
 None
 1.41A 4hytA-5ldrB:
undetectable		 4hytA-5ldrB:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0B_B_SAMB504_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		4 / 8 HIS B 280
ARG B 284
LEU B 655
ILE B 712
 None
 0.96A 4k0bA-5ldrB:
undetectable		 4k0bA-5ldrB:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KR4_C_AICC401_1
(OUTER MEMBRANE
PROTEIN F)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		4 / 8 TYR B 142
ARG B 143
GLU B 323
ARG B 349
 None
 1.22A 4kr4C-5ldrB:
undetectable		 4kr4C-5ldrB:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L7I_B_SAMB501_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		4 / 8 HIS B 280
ARG B 284
LEU B 655
ILE B 712
 None
 1.08A 4l7iA-5ldrB:
undetectable		 4l7iA-5ldrB:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_C_MXMC606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		5 / 12 VAL B 145
ILE B  58
VAL B 114
VAL B  90
ALA B 101
 None
 1.23A 4m11C-5ldrB:
undetectable		 4m11C-5ldrB:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_D_MXMD606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		5 / 12 VAL B 145
ILE B  58
VAL B 114
VAL B  90
ALA B 101
 None
 1.26A 4m11D-5ldrB:
undetectable		 4m11D-5ldrB:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P7N_A_GCSA702_1
(POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		3 / 3 ASP B 134
TYR B 494
TRP B 327
 GAL  B 801 (-3.3A)
None
GAL  B 801 (-4.4A)
 1.40A 4p7nA-5ldrB:
9.2		 4p7nA-5ldrB:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		4 / 7 HIS B 509
TRP B 489
THR B 496
TYR B 135
 None
GAL  B 801 (-3.8A)
None
None
 1.49A 5b1aN-5ldrB:
undetectable
5b1aP-5ldrB:
undetectable		 5b1aN-5ldrB:
20.51
5b1aP-5ldrB:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CVT_B_ACTB200_0
(N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		3 / 3 ASN B 123
ALA B 125
ARG B 338
 None
 0.70A 5cvtB-5ldrB:
2.5		 5cvtB-5ldrB:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBM_A_NVPA601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		5 / 11 PRO B 642
LEU B 655
VAL B 680
GLY B 682
LEU B 647
 None
 1.18A 5hbmA-5ldrB:
undetectable		 5hbmA-5ldrB:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWC_A_FK5A201_1
(FK506-BINDING
PROTEIN 1A)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		5 / 11 ASP B 579
ARG B 596
ILE B 468
ILE B 557
PHE B 583
 None
 1.38A 5hwcA-5ldrB:
undetectable		 5hwcA-5ldrB:
10.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEO_A_VDYA206_2
(CDL2.3A)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		4 / 8 ILE B 640
PRO B 642
LEU B 686
LEU B 638
 None
 0.86A 5ieoA-5ldrB:
undetectable		 5ieoA-5ldrB:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_B_SAMB304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		5 / 10 LEU B 647
GLY B 651
ILE B 712
LEU B 703
ALA B 684
 None
 1.05A 5l0zB-5ldrB:
undetectable		 5l0zB-5ldrB:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJB_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		4 / 8 LEU B 254
LEU B 166
ILE B 160
THR B 162
 None
None
None
CL  B 806 ( 4.7A)
 1.05A 5ljbA-5ldrB:
undetectable		 5ljbA-5ldrB:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OCS_C_ACTC402_0
(PUTATIVE
NADH-DEPENTDENT
FLAVIN
OXIDOREDUCTASE)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		4 / 5 ILE B 133
HIS B 267
HIS B 302
TYR B 135
 None
None
GAL  B 801 (-3.9A)
None
 1.48A 5ocsC-5ldrB:
9.1		 5ocsC-5ldrB:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA503_1
(-)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		5 / 9 VAL B 730
LEU B 647
ILE B 714
PRO B 683
ALA B 684
 None
 1.14A 5og9A-5ldrB:
undetectable		 5og9A-5ldrB:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_B_TESB502_1
(-)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		5 / 12 VAL B 730
LEU B 647
ILE B 714
PRO B 683
ALA B 684
 None
 1.13A 5og9B-5ldrB:
undetectable		 5og9B-5ldrB:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_C_9UQC202_0
(CEREBLON ISOFORM 4)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		4 / 8 PRO B 128
GLU B 122
PHE B 129
TRP B 335
 None
 1.30A 5oh1C-5ldrB:
undetectable		 5oh1C-5ldrB:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V4V_A_NCAA402_0
(NADPH DEHYDROGENASE
3)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		4 / 8 HIS B 470
ASN B 448
PHE B 410
TYR B 494
 None
None
GAL  B 801 (-4.3A)
None
 1.25A 5v4vA-5ldrB:
9.8		 5v4vA-5ldrB:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V4V_B_NCAB402_0
(NADPH DEHYDROGENASE
3)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		4 / 8 HIS B 470
ASN B 448
PHE B 410
TYR B 494
 None
None
GAL  B 801 (-4.3A)
None
 1.27A 5v4vB-5ldrB:
9.6		 5v4vB-5ldrB:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC902_0
(MRNA CAPPING ENZYME
P5)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		5 / 12 LEU B 705
GLY B 710
PRO B 648
ALA B 649
THR B 711
 None
 1.28A 5x6yC-5ldrB:
undetectable		 5x6yC-5ldrB:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BZO_C_FI8C1201_2
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
RNA POLYMERASE SIGMA
FACTOR SIGA)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		4 / 4 LEU B 103
ASP B 102
GLN B  70
VAL B  29
 None
PEG  B 803 ( 4.8A)
None
None
 1.34A 6bzoF-5ldrB:
undetectable		 6bzoF-5ldrB:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5ldr BETA-D-GALACTOSIDASE
(Paracoccus
sp.
32d) 		4 / 7 HIS B 509
TRP B 489
THR B 496
TYR B 135
 None
GAL  B 801 (-3.8A)
None
None
 1.50A 6nmfN-5ldrB:
undetectable
6nmfP-5ldrB:
undetectable		 6nmfN-5ldrB:
20.51
6nmfP-5ldrB:
13.25