SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ldx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PXX_B_DIFB1701_1 (PROSTAGLANDIN G/H SYNTHASE 2)	5ldx	NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 11 (Bos taurus)	5 / 9	VAL Y 4 LEU Y 5 GLY Y 28 ALA Y 30 SER Y 26	None	1.27A	1pxxB-5ldxY: 2.0	1pxxB-5ldxY: 11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AYL_A_FLPA1701_1 (PROSTAGLANDIN G/H SYNTHASE 1)	5ldx	NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 11 (Bos taurus)	5 / 12	VAL Y 4 LEU Y 5 GLY Y 28 ALA Y 30 SER Y 26	None	1.08A	2aylA-5ldxY: undetectable	2aylA-5ldxY: 11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y7K_C_SALC1302_1 (LYSR-TYPE REGULATORY PROTEIN)	5ldx	NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 11 (Bos taurus)	5 / 12	ILE Y 91 GLY Y 92 TYR Y 89 PHE Y 69 GLY Y 118	None	1.27A	2y7kC-5ldxY: undetectable	2y7kC-5ldxY: 21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IKR_A_ID8A601_1 (PROSTAGLANDIN G/H SYNTHASE 2)	5ldx	NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 11 (Bos taurus)	5 / 12	VAL Y 4 LEU Y 5 GLY Y 28 ALA Y 30 SER Y 26	None	1.15A	5ikrA-5ldxY: undetectable	5ikrA-5ldxY: 13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YBB_B_SAMB601_1 (TYPE I RESTRICTION-MODIFICA TION SYSTEM METHYLTRANSFERASE SUBUNIT)	5ldx	NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 11 (Bos taurus)	4 / 7	PHE Y 69 ALA Y 64 GLY Y 66 GLY Y 28	None	0.82A	5ybbB-5ldxY: undetectable	5ybbB-5ldxY: 14.63

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1PXX_B_DIFB1701_1","PROSTAGLANDIN G\/H SYNTHASE 2","5ldx","NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 11","Bos taurus",5,"VAL Y   4;LEU Y   5;GLY Y  28;ALA Y  30;SER Y  26","None","1.27A","1pxxB-5ldxY:2.0","1pxxB-5ldxY:11.93"],["2AYL_A_FLPA1701_1","PROSTAGLANDIN G\/H SYNTHASE 1","5ldx","NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 11","Bos taurus",5,"VAL Y   4;LEU Y   5;GLY Y  28;ALA Y  30;SER Y  26","None","1.08A","2aylA-5ldxY:undetectable","2aylA-5ldxY:11.75"],["2Y7K_C_SALC1302_1","LYSR-TYPE REGULATORY PROTEIN","5ldx","NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 11","Bos taurus",5,"ILE Y  91;GLY Y  92;TYR Y  89;PHE Y  69;GLY Y 118","None","1.27A","2y7kC-5ldxY:undetectable","2y7kC-5ldxY:21.70"],["5IKR_A_ID8A601_1","PROSTAGLANDIN G\/H SYNTHASE 2","5ldx","NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 11","Bos taurus",5,"VAL Y   4;LEU Y   5;GLY Y  28;ALA Y  30;SER Y  26","None","1.15A","5ikrA-5ldxY:undetectable","5ikrA-5ldxY:13.27"],["5YBB_B_SAMB601_1","TYPE I RESTRICTION-MODIFICATION SYSTEM METHYLTRANSFERASE SUBUNIT","5ldx","NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 11","Bos taurus",4,"PHE Y  69;ALA Y  64;GLY Y  66;GLY Y  28","None","0.82A","5ybbB-5ldxY:undetectable","5ybbB-5ldxY:14.63"]]