SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ldy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG2_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 5ldy IG DOMAIN PROTEIN
GROUP 1 DOMAIN
PROTEIN
(Yersinia
pseudotuberculos
is) 		5 / 12 GLY A1883
ILE A1886
GLY A1813
THR A1810
ALA A1756
 None
 1.14A 1jg2A-5ldyA:
undetectable		 1jg2A-5ldyA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_A_SAMA501_0
(BIOTIN SYNTHASE)		 5ldy IG DOMAIN PROTEIN
GROUP 1 DOMAIN
PROTEIN
(Yersinia
pseudotuberculos
is) 		5 / 12 GLY A1710
ASN A1774
ASP A1770
ILE A1776
LEU A1779
 None
 1.23A 1r30A-5ldyA:
undetectable		 1r30A-5ldyA:
24.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_G_BEZG3385_0
(CES1 PROTEIN)		 5ldy IG DOMAIN PROTEIN
GROUP 1 DOMAIN
PROTEIN
(Yersinia
pseudotuberculos
is) 		3 / 3 SER A1647
VAL A1722
LEU A1727
 None
 0.43A 1yajG-5ldyA:
undetectable		 1yajG-5ldyA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_B_SAMB501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 5ldy IG DOMAIN PROTEIN
GROUP 1 DOMAIN
PROTEIN
(Yersinia
pseudotuberculos
is) 		4 / 7 TYR A1870
THR A1952
SER A1975
VAL A1947
 None
 1.21A 2fb2B-5ldyA:
undetectable		 2fb2B-5ldyA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_A_9CRA502_1
(CYTOCHROME P450 2C8)		 5ldy IG DOMAIN PROTEIN
GROUP 1 DOMAIN
PROTEIN
(Yersinia
pseudotuberculos
is) 		5 / 12 SER A1924
ILE A1871
LEU A1894
ASN A1893
VAL A1947
 None
 0.88A 2nnhA-5ldyA:
undetectable		 2nnhA-5ldyA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_2_BO221405_1
(PROTEASOME COMPONENT
PRE3
PROTEASOME COMPONENT
PUP1)		 5ldy IG DOMAIN PROTEIN
GROUP 1 DOMAIN
PROTEIN
(Yersinia
pseudotuberculos
is) 		5 / 12 ALA A1651
SER A1713
GLY A1714
ALA A1716
SER A1687
 None
 1.08A 3mg02-5ldyA:
undetectable
3mg0V-5ldyA:
undetectable		 3mg02-5ldyA:
21.34
3mg0V-5ldyA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 5ldy IG DOMAIN PROTEIN
GROUP 1 DOMAIN
PROTEIN
(Yersinia
pseudotuberculos
is) 		4 / 8 SER A1717
SER A1687
ALA A1651
SER A1664
 None
 1.05A 5l5fY-5ldyA:
undetectable
5l5fZ-5ldyA:
undetectable		 5l5fY-5ldyA:
20.05
5l5fZ-5ldyA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V5Z_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5ldy IG DOMAIN PROTEIN
GROUP 1 DOMAIN
PROTEIN
(Yersinia
pseudotuberculos
is) 		3 / 3 GLY A1888
THR A1810
PRO A1838
 None
 0.58A 5v5zA-5ldyA:
undetectable		 5v5zA-5ldyA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6J_A_ACTA404_0
(L-LYSINE
3-HYDROXYLASE)		 5ldy IG DOMAIN PROTEIN
GROUP 1 DOMAIN
PROTEIN
(Yersinia
pseudotuberculos
is) 		4 / 6 TYR A1703
VAL A1678
ARG A1671
SER A1647
 None
 1.27A 6f6jA-5ldyA:
undetectable		 6f6jA-5ldyA:
undetectable