SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5lf2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_B_BEZB1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 5lf2 LAMININ SUBUNIT
BETA-2
(Rattus
norvegicus) 		5 / 10 LEU A 698
GLY A 715
LEU A 605
ILE A 718
LEU A 671
 None
 1.10A 2f8dB-5lf2A:
undetectable		 2f8dB-5lf2A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OMB_D_IPHD2002_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 5lf2 LAMININ SUBUNIT
BETA-2
(Rattus
norvegicus) 		4 / 7 HIS A 569
PRO A 565
PRO A 725
TYR A 780
 CL  A1002 ( 4.7A)
None
None
None
 1.31A 2ombC-5lf2A:
undetectable
2ombD-5lf2A:
undetectable		 2ombC-5lf2A:
23.58
2ombD-5lf2A:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5lf2 LAMININ SUBUNIT
BETA-2
(Rattus
norvegicus) 		4 / 6 GLU A 731
GLY A 735
GLY A 736
ASP A 737
 None
 0.84A 5a06D-5lf2A:
undetectable		 5a06D-5lf2A:
22.87