SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5lf7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_J_ACTJ1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 5lf7 PROTEASOME SUBUNIT
BETA TYPE-1
(Homo
sapiens) 		4 / 8 GLU L 206
ILE L 195
ILE L  22
LYS L 176
 None
 0.96A 2j9dJ-5lf7L:
undetectable
2j9dK-5lf7L:
undetectable
2j9dL-5lf7L:
1.3		 2j9dJ-5lf7L:
17.84
2j9dK-5lf7L:
17.84
2j9dL-5lf7L:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0Y_A_SAMA300_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0657)		 5lf7 PROTEASOME SUBUNIT
BETA TYPE-1
(Homo
sapiens) 		5 / 9 ALA L 141
GLY L  10
LEU L 145
ILE L 109
LEU L  13
 None
 0.88A 2z0yA-5lf7L:
undetectable		 2z0yA-5lf7L:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0Y_B_SAMB400_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0657)		 5lf7 PROTEASOME SUBUNIT
BETA TYPE-1
(Homo
sapiens) 		5 / 9 ALA L 141
GLY L  10
LEU L 145
ILE L 109
LEU L  13
 None
 0.95A 2z0yB-5lf7L:
undetectable		 2z0yB-5lf7L:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5lf7 PROTEASOME SUBUNIT
BETA TYPE-1
(Homo
sapiens) 		5 / 10 ILE L  52
ILE L 110
GLY L  86
VAL L 198
LEU L  72
 None
 1.30A 3elzB-5lf7L:
1.7		 3elzB-5lf7L:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5lf7 PROTEASOME SUBUNIT
BETA TYPE-1
(Homo
sapiens) 		5 / 10 ILE L  12
ILE L 109
VAL L 121
GLY L 112
VAL L 175
 None
 1.23A 3em0A-5lf7L:
undetectable		 3em0A-5lf7L:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6E_A_SAMA1349_0
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 5lf7 PROTEASOME SUBUNIT
BETA TYPE-1
(Homo
sapiens) 		5 / 12 LEU L  46
GLY L 111
ILE L  12
VAL L  23
ALA L  89
 None
 1.05A 4a6eA-5lf7L:
undetectable		 4a6eA-5lf7L:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FZV_A_SAMA401_0
(PUTATIVE
METHYLTRANSFERASE
NSUN4)		 5lf7 PROTEASOME SUBUNIT
BETA TYPE-1
(Homo
sapiens) 		5 / 12 GLY L 139
GLY L 138
SER L  30
GLY L  59
LEU L  62
 None
 1.08A 4fzvA-5lf7L:
undetectable		 4fzvA-5lf7L:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_A_20JA601_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 5lf7 PROTEASOME SUBUNIT
BETA TYPE-1
(Homo
sapiens) 		4 / 8 ASP L 186
SER L 140
SER L  30
ARG L  28
 None
None
None
K  L 302 ( 4.6A)
 0.95A 4lv9A-5lf7L:
undetectable
4lv9B-5lf7L:
undetectable		 4lv9A-5lf7L:
19.56
4lv9B-5lf7L:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_B_20JB601_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 5lf7 PROTEASOME SUBUNIT
BETA TYPE-1
(Homo
sapiens) 		4 / 7 ASP L 186
SER L 140
SER L  30
ARG L  28
 None
None
None
K  L 302 ( 4.6A)
 0.95A 4lv9A-5lf7L:
undetectable
4lv9B-5lf7L:
undetectable		 4lv9A-5lf7L:
19.56
4lv9B-5lf7L:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_A_TLFA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5lf7 PROTEASOME SUBUNIT
BETA TYPE-1
(Homo
sapiens) 		3 / 3 LEU L  62
TYR L  44
SER L  40
 None
 0.86A 5iktA-5lf7L:
undetectable		 5iktA-5lf7L:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZJ_A_TEPA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 5lf7 PROTEASOME SUBUNIT
BETA TYPE-1
(Homo
sapiens) 		4 / 8 LEU L  46
LEU L  92
ASN L 108
ILE L  95
 None
 0.96A 5mzjA-5lf7L:
undetectable		 5mzjA-5lf7L:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7P_A_SAMA501_0
(OXAC)		 5lf7 PROTEASOME SUBUNIT
BETA TYPE-1
(Homo
sapiens) 		5 / 12 ALA L 137
GLY L 138
SER L 142
LEU L 174
ASP L 150
 None
 1.18A 5w7pA-5lf7L:
undetectable		 5w7pA-5lf7L:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWO_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 5lf7 PROTEASOME SUBUNIT
BETA TYPE-1
(Homo
sapiens) 		5 / 9 ASP L 169
ALA L  21
ILE L  22
SER L 167
GLY L  17
 None
 1.34A 6awoA-5lf7L:
undetectable		 6awoA-5lf7L:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWQ_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 5lf7 PROTEASOME SUBUNIT
BETA TYPE-1
(Homo
sapiens) 		5 / 9 ASP L 169
ALA L  21
ILE L  22
SER L 167
GLY L  17
 None
 1.34A 6awqA-5lf7L:
undetectable		 6awqA-5lf7L:
18.20