SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5lf9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_C_DEXC3999_1
(GLUCOCORTICOID
RECEPTOR)		 5lf9 NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 22
(Homo
sapiens) 		5 / 12 ASN A  94
GLY A 218
LEU A   8
LEU A 121
THR A  85
 None
 1.38A 1p93C-5lf9A:
undetectable		 1p93C-5lf9A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LP9_D_SPMD230_1
(LS-24)		 5lf9 NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 22
(Homo
sapiens) 		3 / 3 GLU A 145
GLU A   4
ASN A 213
 None
 0.84A 3lp9B-5lf9A:
undetectable
3lp9D-5lf9A:
undetectable		 3lp9B-5lf9A:
21.27
3lp9D-5lf9A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_A_SAMA201_0
(YAEB-LIKE PROTEIN
RPA0152)		 5lf9 NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 22
(Homo
sapiens) 		5 / 12 LEU A 197
CYH A 192
PRO A 153
GLY A 124
LEU A 202
 None
 1.36A 3okxA-5lf9A:
undetectable		 3okxA-5lf9A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_1
(YAEB-LIKE PROTEIN
RPA0152)		 5lf9 NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 22
(Homo
sapiens) 		5 / 12 LEU A 197
CYH A 192
PRO A 153
GLY A 124
LEU A 202
 None
 1.31A 3okxB-5lf9A:
undetectable		 3okxB-5lf9A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB160_0
(HEME-BINDING PROTEIN
HUTZ)		 5lf9 NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 22
(Homo
sapiens) 		4 / 4 LEU A 207
GLY A 209
LEU A 208
GLU A 223
 None
 1.00A 3tgvB-5lf9A:
undetectable		 3tgvB-5lf9A:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UVV_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5lf9 NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 22
(Homo
sapiens) 		5 / 12 ALA A 279
ALA A 276
LEU A 272
VAL A 195
ILE A 252
 None
 1.31A 3uvvB-5lf9A:
undetectable		 3uvvB-5lf9A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_2
(ENVELOPE
GLYCOPROTEIN 2)		 5lf9 NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 22
(Homo
sapiens) 		4 / 7 LEU A 208
TYR A 225
THR A 129
ASP A 132
 None
 0.98A 5jq7B-5lf9A:
0.2		 5jq7B-5lf9A:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_0
(REGULATORY PROTEIN
TETR)		 5lf9 NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 22
(Homo
sapiens) 		5 / 12 ALA A  99
LEU A  34
ILE A  41
ARG A  88
ASP A  30
 None
 1.29A 5vlmG-5lf9A:
undetectable		 5vlmG-5lf9A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		 5lf9 NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 22
(Homo
sapiens) 		5 / 9 SER A 275
VAL A 123
ALA A 222
SER A 221
GLY A 209
 None
 1.24A 6bklA-5lf9A:
undetectable
6bklB-5lf9A:
undetectable
6bklC-5lf9A:
undetectable
6bklD-5lf9A:
undetectable		 6bklA-5lf9A:
6.82
6bklB-5lf9A:
6.82
6bklC-5lf9A:
6.82
6bklD-5lf9A:
6.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA811_0
(GEPHYRIN)		 5lf9 NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 22
(Homo
sapiens) 		3 / 3 LEU A 102
LEU A  34
ARG A  31
 None
 0.53A 6fgcA-5lf9A:
undetectable		 6fgcA-5lf9A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA810_0
(GEPHYRIN)		 5lf9 NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 22
(Homo
sapiens) 		3 / 3 LEU A 102
LEU A  34
ARG A  31
 None
 0.48A 6fgdA-5lf9A:
undetectable		 6fgdA-5lf9A:
23.36