SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5lg8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_C_DESC500_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 5lg8 FERRITIN LIGHT CHAIN
(Homo
sapiens) 		5 / 12 LEU A 120
LEU A 117
LEU A 114
ALA A 113
LEU A  26
 None
 0.74A 1s9pC-5lg8A:
undetectable		 1s9pC-5lg8A:
23.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RD0_A_EDPA175_1
(FERRITIN LIGHT CHAIN)		 5lg8 FERRITIN LIGHT CHAIN
(Homo
sapiens) 		4 / 6 LEU A  28
SER A  31
TYR A  32
ALA A  59
 None
 0.33A 3rd0A-5lg8A:
29.1		 3rd0A-5lg8A:
87.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F3T_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 5lg8 FERRITIN LIGHT CHAIN
(Homo
sapiens) 		4 / 6 TYR A  27
LYS A  62
LEU A 106
GLU A 107
 None
 0.88A 4f3tA-5lg8A:
undetectable		 4f3tA-5lg8A:
10.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLA_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 5lg8 FERRITIN LIGHT CHAIN
(Homo
sapiens) 		4 / 5 TYR A  27
LYS A  62
LEU A 106
GLU A 107
 None
 0.99A 4olaA-5lg8A:
undetectable		 4olaA-5lg8A:
10.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 5lg8 FERRITIN LIGHT CHAIN
(Homo
sapiens) 		4 / 6 TYR A  27
LYS A  62
LEU A 106
GLU A 107
 None
 0.92A 4z4cA-5lg8A:
undetectable		 4z4cA-5lg8A:
10.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4H_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 5lg8 FERRITIN LIGHT CHAIN
(Homo
sapiens) 		4 / 5 TYR A  27
LYS A  62
LEU A 106
GLU A 107
 None
 0.94A 4z4hA-5lg8A:
undetectable		 4z4hA-5lg8A:
10.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS1_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 5lg8 FERRITIN LIGHT CHAIN
(Homo
sapiens) 		4 / 5 TYR A  27
LYS A  62
LEU A 106
GLU A 107
 None
 0.84A 5js1A-5lg8A:
undetectable		 5js1A-5lg8A:
10.91