SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5lhv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_A_ADNA1260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 10 ARG A  90
THR A  93
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
SO4  A 301 ( 2.9A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.28A 1jdvA-5lhvA:
16.0
1jdvD-5lhvA:
31.3		 1jdvA-5lhvA:
31.27
1jdvD-5lhvA:
31.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_B_ADNB2260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 10 ARG A  90
THR A  93
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
SO4  A 301 ( 2.9A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.28A 1jdvB-5lhvA:
31.4
1jdvC-5lhvA:
32.0		 1jdvB-5lhvA:
31.27
1jdvC-5lhvA:
31.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_D_ADND3260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 10 ARG A  90
THR A  93
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
SO4  A 301 ( 2.9A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.27A 1jdvA-5lhvA:
16.0
1jdvD-5lhvA:
31.3		 1jdvA-5lhvA:
31.27
1jdvD-5lhvA:
31.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_E_ADNE4260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 12 ARG A  90
THR A  93
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.28A 1jdvE-5lhvA:
31.4
1jdvF-5lhvA:
31.9		 1jdvE-5lhvA:
31.27
1jdvF-5lhvA:
31.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_A_ADNA1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 11 ARG A  90
GLY A  95
GLU A 195
GLU A 197
ILE A  97
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 (-2.7A)
None
 1.34A 1odiA-5lhvA:
24.5		 1odiA-5lhvA:
33.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_A_ADNA1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 11 ARG A  90
THR A  93
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.32A 1odiA-5lhvA:
24.5		 1odiA-5lhvA:
33.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_B_ADNB1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 11 ARG A  90
THR A  93
GLY A  95
GLU A 195
GLU A 197
ILE A  97
 SO4  A 301 ( 3.0A)
SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 (-2.7A)
None
 1.24A 1odiB-5lhvA:
33.5		 1odiB-5lhvA:
33.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_B_ADNB1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 11 ARG A  90
THR A  93
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.32A 1odiB-5lhvA:
33.5		 1odiB-5lhvA:
33.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_C_ADNC1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 11 ARG A  90
THR A  93
GLY A  95
GLU A 195
GLU A 197
ILE A  97
 SO4  A 301 ( 3.0A)
SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 (-2.7A)
None
 1.23A 1odiC-5lhvA:
33.5		 1odiC-5lhvA:
33.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_C_ADNC1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 11 ARG A  90
THR A  93
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.32A 1odiC-5lhvA:
33.5		 1odiC-5lhvA:
33.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_D_ADND1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 11 ARG A  90
GLY A  95
GLU A 195
GLU A 197
ILE A  97
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 (-2.7A)
None
 1.32A 1odiD-5lhvA:
33.4		 1odiD-5lhvA:
33.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_D_ADND1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 11 ARG A  90
GLY A 217
GLU A 195
GLU A 197
SER A 240
 SO4  A 301 ( 3.0A)
None
URI  A 303 ( 4.6A)
URI  A 303 (-2.7A)
None
 1.31A 1odiD-5lhvA:
33.4		 1odiD-5lhvA:
33.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_D_ADND1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 11 ARG A  90
THR A  93
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.32A 1odiD-5lhvA:
33.4		 1odiD-5lhvA:
33.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_E_ADNE1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 11 ARG A  90
GLY A  95
GLU A 195
GLU A 197
ILE A  97
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 (-2.7A)
None
 1.32A 1odiE-5lhvA:
33.6		 1odiE-5lhvA:
33.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_E_ADNE1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 11 ARG A  90
GLY A 217
GLU A 195
GLU A 197
SER A 240
 SO4  A 301 ( 3.0A)
None
URI  A 303 ( 4.6A)
URI  A 303 (-2.7A)
None
 1.26A 1odiE-5lhvA:
33.6		 1odiE-5lhvA:
33.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_E_ADNE1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 11 ARG A  90
THR A  93
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.32A 1odiE-5lhvA:
33.6		 1odiE-5lhvA:
33.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_F_ADNF1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 11 ARG A  90
GLY A 217
GLU A 195
GLU A 197
SER A 240
 SO4  A 301 ( 3.0A)
None
URI  A 303 ( 4.6A)
URI  A 303 (-2.7A)
None
 1.30A 1odiF-5lhvA:
33.2		 1odiF-5lhvA:
33.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_F_ADNF1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 11 ARG A  90
THR A  93
GLY A  95
GLU A 195
GLU A 197
ILE A  97
 SO4  A 301 ( 3.0A)
SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 (-2.7A)
None
 1.28A 1odiF-5lhvA:
33.2		 1odiF-5lhvA:
33.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_F_ADNF1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 11 ARG A  90
THR A  93
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.32A 1odiF-5lhvA:
33.2		 1odiF-5lhvA:
33.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK7_A_ADNA1245_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 9 ARG A  90
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.26A 1pk7A-5lhvA:
31.9		 1pk7A-5lhvA:
31.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK7_C_ADNC1247_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 10 ARG A  90
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.26A 1pk7C-5lhvA:
31.6		 1pk7C-5lhvA:
31.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_A_2FAA306_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 10 ARG A  90
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.23A 1pk9A-5lhvA:
31.9		 1pk9A-5lhvA:
31.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_B_2FAB307_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 9 ARG A  90
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.23A 1pk9B-5lhvA:
31.9		 1pk9B-5lhvA:
31.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_C_2FAC308_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 11 ARG A  90
GLY A  95
GLU A 195
MET A 196
GLU A 197
ILE A  97
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
None
 1.31A 1pk9C-5lhvA:
30.2		 1pk9C-5lhvA:
31.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_A_RABA645_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 10 ARG A  90
GLY A  95
GLU A 195
MET A 196
GLU A 197
ILE A  97
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
None
 1.44A 1pw7A-5lhvA:
31.9		 1pw7A-5lhvA:
31.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_A_RABA645_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 10 ARG A  90
GLY A  95
GLU A 195
MET A 196
GLU A 197
ILE A 220
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
URA  A 304 (-4.3A)
 1.47A 1pw7A-5lhvA:
31.9		 1pw7A-5lhvA:
31.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_B_RABB646_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 9 ARG A  90
GLY A  95
GLU A 195
MET A 196
GLU A 197
ILE A  97
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
None
 1.34A 1pw7B-5lhvA:
31.7		 1pw7B-5lhvA:
31.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RXC_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 8 THR A  93
GLY A  95
GLN A 165
ARG A 167
MET A 196
ILE A 219
 SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
None
 0.23A 1rxcB-5lhvA:
24.3		 1rxcB-5lhvA:
75.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RXC_C_URFC2081_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 7 GLY A  95
GLN A 165
ARG A 167
MET A 196
ILE A 219
 URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
None
 0.29A 1rxcC-5lhvA:
42.9		 1rxcC-5lhvA:
75.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RXC_D_URFD2021_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 7 GLY A  95
GLN A 165
ARG A 167
MET A 196
ILE A 219
 URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
None
 0.26A 1rxcD-5lhvA:
43.7		 1rxcD-5lhvA:
75.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RXC_E_URFE2031_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 8 THR A  93
GLY A  95
GLN A 165
ARG A 167
MET A 196
ILE A 219
 SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
None
 0.17A 1rxcE-5lhvA:
43.7		 1rxcE-5lhvA:
75.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RXC_F_URFF2001_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 7 GLY A  95
GLN A 165
ARG A 167
MET A 196
ILE A 219
 URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
None
 0.22A 1rxcF-5lhvA:
43.8		 1rxcF-5lhvA:
75.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RXC_I_URFI2041_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 8 THR A  93
GLY A  95
GLN A 165
ARG A 167
MET A 196
ILE A 219
 SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
None
 0.26A 1rxcI-5lhvA:
44.0		 1rxcI-5lhvA:
75.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RXC_K_URFK2061_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 8 THR A  93
GLY A  95
GLN A 165
ARG A 167
MET A 196
ILE A 219
 SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
None
 0.22A 1rxcK-5lhvA:
42.1		 1rxcK-5lhvA:
75.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RXC_L_URFL2071_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 7 GLY A  95
GLN A 165
ARG A 167
MET A 196
ILE A 219
 URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
None
 0.19A 1rxcL-5lhvA:
43.8		 1rxcL-5lhvA:
75.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_A_ADNA252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 11 ARG A  90
GLY A  95
GLU A 195
MET A 196
GLU A 197
ILE A  97
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
None
 1.37A 1vhwA-5lhvA:
32.3
1vhwD-5lhvA:
32.4		 1vhwA-5lhvA:
26.81
1vhwD-5lhvA:
26.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_C_ADNC252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 11 ARG A  90
GLY A  95
GLU A 195
MET A 196
GLU A 197
ILE A  97
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
None
 1.42A 1vhwC-5lhvA:
32.4
1vhwE-5lhvA:
32.2		 1vhwC-5lhvA:
26.81
1vhwE-5lhvA:
26.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_C_ADNC252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 11 ARG A  90
GLY A  95
GLU A 195
MET A 196
GLU A 197
ILE A 220
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
URA  A 304 (-4.3A)
 1.46A 1vhwC-5lhvA:
32.4
1vhwE-5lhvA:
32.2		 1vhwC-5lhvA:
26.81
1vhwE-5lhvA:
26.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_D_ADND252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 11 ARG A  90
GLY A  95
GLU A 195
MET A 196
GLU A 197
ILE A  97
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
None
 1.40A 1vhwA-5lhvA:
32.3
1vhwD-5lhvA:
32.4		 1vhwA-5lhvA:
26.81
1vhwD-5lhvA:
26.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_D_ADND252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 11 ARG A  90
GLY A  95
GLU A 195
MET A 196
GLU A 197
ILE A 220
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
URA  A 304 (-4.3A)
 1.47A 1vhwA-5lhvA:
32.3
1vhwD-5lhvA:
32.4		 1vhwA-5lhvA:
26.81
1vhwD-5lhvA:
26.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_E_ADNE252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 11 ARG A  90
GLY A  95
GLU A 195
MET A 196
GLU A 197
ILE A  97
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
None
 1.37A 1vhwC-5lhvA:
32.4
1vhwE-5lhvA:
32.2		 1vhwC-5lhvA:
26.81
1vhwE-5lhvA:
26.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_F_ADNF252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 10 ARG A  90
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.35A 1vhwB-5lhvA:
32.2
1vhwF-5lhvA:
31.8		 1vhwB-5lhvA:
26.81
1vhwF-5lhvA:
26.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_A_SAMA3142_0
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 12 THR A  50
GLY A  25
GLY A  67
GLN A  31
PHE A  42
 None
SO4  A 301 (-3.3A)
NA  A 307 ( 4.0A)
None
None
 1.18A 1wg8A-5lhvA:
undetectable		 1wg8A-5lhvA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_B_SAMB3141_0
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 12 THR A  50
GLY A  25
GLY A  67
GLN A  31
PHE A  42
 None
SO4  A 301 (-3.3A)
NA  A 307 ( 4.0A)
None
None
 1.19A 1wg8B-5lhvA:
undetectable		 1wg8B-5lhvA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_A_ACTA2001_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		4 / 5 SER A 112
SER A 198
THR A 155
ASN A 193
 None
 1.28A 1yvpA-5lhvA:
undetectable		 1yvpA-5lhvA:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_B_ACTB2002_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		4 / 6 SER A 112
ALA A 199
SER A 198
THR A 155
 None
 0.87A 1yvpB-5lhvA:
undetectable		 1yvpB-5lhvA:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_B_ACTB2002_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		4 / 6 SER A 112
SER A 198
THR A 155
ASN A 193
 None
 1.18A 1yvpB-5lhvA:
undetectable		 1yvpB-5lhvA:
16.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z35_A_2FAA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 10 ARG A  90
THR A  93
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.45A 1z35A-5lhvA:
31.4		 1z35A-5lhvA:
30.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z37_A_ADNA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 9 ARG A  90
THR A  93
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.37A 1z37A-5lhvA:
31.4		 1z37A-5lhvA:
30.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AC7_A_ADNA1216_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 11 ARG A  90
THR A  93
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.30A 2ac7A-5lhvA:
30.2
2ac7B-5lhvA:
30.2		 2ac7A-5lhvA:
33.46
2ac7B-5lhvA:
33.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AC7_B_ADNB1215_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 11 ARG A  90
THR A  93
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.30A 2ac7A-5lhvA:
30.2
2ac7B-5lhvA:
30.2		 2ac7A-5lhvA:
33.46
2ac7B-5lhvA:
33.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I91_A_ACTA601_0
(60 KDA SS-A/RO
RIBONUCLEOPROTEIN)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		4 / 7 SER A 112
ALA A 199
SER A 198
THR A 155
 None
 0.85A 2i91A-5lhvA:
undetectable		 2i91A-5lhvA:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I91_B_ACTB602_0
(60 KDA SS-A/RO
RIBONUCLEOPROTEIN)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		4 / 7 SER A 112
ALA A 199
SER A 198
THR A 155
 None
 0.85A 2i91B-5lhvA:
undetectable		 2i91B-5lhvA:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_1
(ESTROGEN RECEPTOR)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 12 THR A  73
ALA A  76
GLU A  79
LEU A  80
LEU A   8
 None
 0.81A 2jfaA-5lhvA:
undetectable		 2jfaA-5lhvA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_A_RALA600_1
(ESTROGEN RECEPTOR)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 12 THR A  73
ALA A  76
GLU A  79
LEU A  80
LEU A   8
 None
 0.94A 2qxsA-5lhvA:
undetectable		 2qxsA-5lhvA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A7E_A_SAMA216_1
(CATECHOL
O-METHYLTRANSFERASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		4 / 6 GLY A  25
ILE A  23
GLU A 197
ASP A  26
 SO4  A 301 (-3.3A)
None
URI  A 303 (-2.7A)
None
 0.97A 3a7eA-5lhvA:
undetectable		 3a7eA-5lhvA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIA_B_SAMB206_0
(UPF0217 PROTEIN
MJ1640)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		4 / 5 SER A  72
GLY A  25
GLU A  48
CYH A  64
 NA  A 307 (-2.9A)
SO4  A 301 (-3.3A)
NA  A 307 (-3.7A)
None
 1.22A 3aiaA-5lhvA:
1.8
3aiaB-5lhvA:
undetectable		 3aiaA-5lhvA:
21.26
3aiaB-5lhvA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_A_URFA2001_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 10 PHE A 161
GLN A 165
ARG A 167
GLU A 195
MET A 196
ILE A 220
 URI  A 303 (-4.3A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URA  A 304 (-4.3A)
 1.18A 3kvrA-5lhvA:
26.1		 3kvrA-5lhvA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_A_URFA2001_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		7 / 10 THR A  93
GLY A  95
PHE A 161
GLN A 165
ARG A 167
GLU A 195
MET A 196
 SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URI  A 303 (-4.3A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
 0.33A 3kvrA-5lhvA:
26.1		 3kvrA-5lhvA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		7 / 10 THR A  93
GLY A  95
PHE A 161
GLN A 165
ARG A 167
GLU A 195
MET A 196
 SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URI  A 303 (-4.3A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
 0.30A 3kvrB-5lhvA:
26.0		 3kvrB-5lhvA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 10 THR A  93
PHE A 161
GLN A 165
ARG A 167
MET A 196
ILE A 220
 SO4  A 301 ( 2.9A)
URI  A 303 (-4.3A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
URA  A 304 (-4.3A)
 1.35A 3kvrB-5lhvA:
26.0		 3kvrB-5lhvA:
25.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KVV_A_URFA254_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 6 GLY A  95
GLN A 165
ARG A 167
MET A 196
ILE A 219
 URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
None
 0.18A 3kvvA-5lhvA:
44.2		 3kvvA-5lhvA:
75.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KVV_B_URFB254_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 6 GLY A  95
GLN A 165
ARG A 167
MET A 196
ILE A 219
 URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
None
 0.16A 3kvvB-5lhvA:
43.8		 3kvvB-5lhvA:
75.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KVV_C_URFC254_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 6 GLY A  95
GLN A 165
ARG A 167
MET A 196
ILE A 219
 URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
None
 0.17A 3kvvC-5lhvA:
43.3		 3kvvC-5lhvA:
75.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KVV_D_URFD254_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 6 GLY A  95
GLN A 165
ARG A 167
MET A 196
ILE A 219
 URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
None
 0.19A 3kvvD-5lhvA:
43.5		 3kvvD-5lhvA:
75.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KVV_E_URFE254_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 6 GLY A  95
GLN A 165
ARG A 167
MET A 196
ILE A 219
 URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
None
 0.11A 3kvvE-5lhvA:
44.5		 3kvvE-5lhvA:
75.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KVV_F_URFF254_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 6 GLY A  95
GLN A 165
ARG A 167
MET A 196
ILE A 219
 URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
None
 0.18A 3kvvF-5lhvA:
42.8		 3kvvF-5lhvA:
75.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_A_URFA400_1
(URIDINE
PHOSPHORYLASE 1)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 9 GLN A 165
ARG A 167
GLU A 195
MET A 196
ILE A 220
 URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URA  A 304 (-4.3A)
 1.06A 3nbqA-5lhvA:
26.0		 3nbqA-5lhvA:
25.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_A_URFA400_1
(URIDINE
PHOSPHORYLASE 1)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 9 THR A  93
GLY A  95
GLN A 165
ARG A 167
GLU A 195
MET A 196
 SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
 0.32A 3nbqA-5lhvA:
26.0		 3nbqA-5lhvA:
25.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_B_URFB400_1
(URIDINE
PHOSPHORYLASE 1)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 8 THR A  93
GLY A  95
GLN A 165
ARG A 167
MET A 196
 SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
 0.33A 3nbqB-5lhvA:
26.0		 3nbqB-5lhvA:
25.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_C_URFC400_1
(URIDINE
PHOSPHORYLASE 1)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 8 THR A  93
GLY A  95
GLN A 165
ARG A 167
MET A 196
 SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
 0.28A 3nbqC-5lhvA:
25.9		 3nbqC-5lhvA:
25.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_D_URFD400_1
(URIDINE
PHOSPHORYLASE 1)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 9 THR A  93
GLY A  95
GLN A 165
ARG A 167
MET A 196
ARG A 222
 SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
None
 0.50A 3nbqD-5lhvA:
26.1		 3nbqD-5lhvA:
25.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_C_ADNC251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 12 ARG A  90
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.24A 3u40B-5lhvA:
30.2
3u40C-5lhvA:
13.2		 3u40B-5lhvA:
26.79
3u40C-5lhvA:
26.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_D_ADND251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 11 ARG A  90
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.21A 3u40D-5lhvA:
30.4
3u40E-5lhvA:
29.7		 3u40D-5lhvA:
26.79
3u40E-5lhvA:
26.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_E_ADNE251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 12 ARG A  90
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.30A 3u40D-5lhvA:
30.4
3u40E-5lhvA:
29.7		 3u40D-5lhvA:
26.79
3u40E-5lhvA:
26.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UAW_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 11 ARG A  90
THR A  93
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.32A 3uawA-5lhvA:
14.1		 3uawA-5lhvA:
33.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UAY_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 10 ARG A  90
GLY A  95
GLU A 195
GLU A 197
ILE A  97
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 (-2.7A)
None
 1.39A 3uayA-5lhvA:
13.0		 3uayA-5lhvA:
33.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UAY_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 10 ARG A  90
GLY A  95
GLU A 195
MET A 196
GLU A 197
ILE A 220
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
URA  A 304 (-4.3A)
 1.50A 3uayA-5lhvA:
13.0		 3uayA-5lhvA:
33.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UAY_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 10 ARG A  90
THR A  93
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.32A 3uayA-5lhvA:
13.0		 3uayA-5lhvA:
33.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_B_SALB1345_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		4 / 8 LEU A  15
VAL A   5
LEU A   8
ALA A  44
 None
 0.84A 3uniB-5lhvA:
undetectable		 3uniB-5lhvA:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D9H_A_ADNA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 11 ARG A  90
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.26A 4d9hA-5lhvA:
30.7		 4d9hA-5lhvA:
28.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DA7_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 10 ARG A  90
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.30A 4da7A-5lhvA:
30.5		 4da7A-5lhvA:
28.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAN_A_2FAA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 11 ARG A  90
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.28A 4danA-5lhvA:
30.1		 4danA-5lhvA:
28.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAN_B_2FAB301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 12 ARG A  90
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.36A 4danA-5lhvA:
30.1
4danB-5lhvA:
30.2		 4danA-5lhvA:
28.88
4danB-5lhvA:
28.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E1V_A_URFA1301_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 8 THR A  93
GLY A  95
GLN A 165
ARG A 167
MET A 196
ILE A 219
 SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
None
 0.20A 4e1vA-5lhvA:
42.1		 4e1vA-5lhvA:
75.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E1V_B_URFB1301_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 7 GLY A  95
GLN A 165
ARG A 167
MET A 196
ILE A 219
 URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
None
 0.18A 4e1vB-5lhvA:
20.0		 4e1vB-5lhvA:
75.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E1V_C_URFC1301_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 8 THR A  93
GLY A  95
GLN A 165
ARG A 167
MET A 196
ILE A 219
 SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
None
 0.18A 4e1vC-5lhvA:
20.2		 4e1vC-5lhvA:
75.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E1V_D_URFD1301_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 8 THR A  93
GLY A  95
GLN A 165
ARG A 167
MET A 196
ILE A 219
 SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
None
 0.17A 4e1vD-5lhvA:
42.2		 4e1vD-5lhvA:
75.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E1V_E_URFE1301_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 8 THR A  93
GLY A  95
GLN A 165
ARG A 167
MET A 196
ILE A 219
 SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
None
 0.18A 4e1vE-5lhvA:
42.2		 4e1vE-5lhvA:
75.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E1V_F_URFF1301_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 6 GLY A  95
GLN A 165
ARG A 167
MET A 196
ILE A 219
 URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
None
 0.23A 4e1vF-5lhvA:
41.8		 4e1vF-5lhvA:
75.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E1V_G_URFG1301_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 8 THR A  93
GLY A  95
GLN A 165
ARG A 167
MET A 196
ILE A 219
 SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
None
 0.40A 4e1vG-5lhvA:
19.1		 4e1vG-5lhvA:
75.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E1V_H_URFH1301_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 8 THR A  93
GLY A  95
GLN A 165
ARG A 167
MET A 196
ILE A 219
 SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
None
 0.17A 4e1vH-5lhvA:
19.6		 4e1vH-5lhvA:
75.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MDA_A_RLTA403_1
(MARINER MOS1
TRANSPOSASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		4 / 6 ASP A  38
ASN A  39
ALA A  54
ASP A  57
 None
 1.20A 4mdaA-5lhvA:
undetectable		 4mdaA-5lhvA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 12 SER A 198
THR A  93
THR A  94
ALA A 216
THR A  73
 None
SO4  A 301 ( 2.9A)
None
None
None
 1.18A 4qvnV-5lhvA:
undetectable
4qvnb-5lhvA:
undetectable		 4qvnV-5lhvA:
20.45
4qvnb-5lhvA:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 12 SER A 198
THR A  93
THR A  94
ALA A 216
THR A  73
 None
SO4  A 301 ( 2.9A)
None
None
None
 1.17A 4qvnH-5lhvA:
undetectable
4qvnN-5lhvA:
undetectable		 4qvnH-5lhvA:
20.45
4qvnN-5lhvA:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_A_URFA302_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 7 THR A  93
GLN A 165
ARG A 167
MET A 196
ILE A 220
 SO4  A 301 ( 2.9A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
URA  A 304 (-4.3A)
 1.39A 4txnA-5lhvA:
25.0		 4txnA-5lhvA:
25.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_A_URFA302_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 7 THR A  93
GLY A  95
GLN A 165
ARG A 167
MET A 196
 SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
 0.36A 4txnA-5lhvA:
25.0		 4txnA-5lhvA:
25.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_B_URFB302_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 7 THR A  93
GLN A 165
ARG A 167
MET A 196
ILE A 220
 SO4  A 301 ( 2.9A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
URA  A 304 (-4.3A)
 1.37A 4txnB-5lhvA:
25.0		 4txnB-5lhvA:
25.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_B_URFB302_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 7 THR A  93
GLY A  95
GLN A 165
ARG A 167
MET A 196
 SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
 0.39A 4txnB-5lhvA:
25.0		 4txnB-5lhvA:
25.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_C_URFC302_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 7 THR A  93
GLN A 165
ARG A 167
MET A 196
ILE A 220
 SO4  A 301 ( 2.9A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
URA  A 304 (-4.3A)
 1.40A 4txnC-5lhvA:
25.0		 4txnC-5lhvA:
25.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_C_URFC302_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 7 THR A  93
GLY A  95
GLN A 165
ARG A 167
MET A 196
 SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
 0.36A 4txnC-5lhvA:
25.0		 4txnC-5lhvA:
25.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_D_URFD302_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 7 THR A  93
GLN A 165
ARG A 167
MET A 196
ILE A 220
 SO4  A 301 ( 2.9A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
URA  A 304 (-4.3A)
 1.38A 4txnD-5lhvA:
24.9		 4txnD-5lhvA:
25.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_D_URFD302_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 7 THR A  93
GLY A  95
GLN A 165
ARG A 167
MET A 196
 SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
 0.38A 4txnD-5lhvA:
24.9		 4txnD-5lhvA:
25.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_2
(ADENOSINE KINASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		4 / 4 ALA A 216
VAL A 108
GLY A 111
THR A 155
 None
 1.11A 4ubeA-5lhvA:
undetectable		 4ubeA-5lhvA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 12 GLY A  69
GLU A 197
GLY A  67
GLY A  25
SER A  72
ALA A 118
 None
URI  A 303 (-2.7A)
NA  A 307 ( 4.0A)
SO4  A 301 (-3.3A)
NA  A 307 (-2.9A)
None
 1.32A 4uciA-5lhvA:
undetectable		 4uciA-5lhvA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 12 GLY A  69
GLU A 197
GLY A  67
GLY A  25
SER A  72
ALA A 118
 None
URI  A 303 (-2.7A)
NA  A 307 ( 4.0A)
SO4  A 301 (-3.3A)
NA  A 307 (-2.9A)
None
 1.32A 4uciB-5lhvA:
undetectable		 4uciB-5lhvA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 12 GLY A  69
GLU A 197
GLY A  67
GLY A  25
SER A  72
ALA A 118
 None
URI  A 303 (-2.7A)
NA  A 307 ( 4.0A)
SO4  A 301 (-3.3A)
NA  A 307 (-2.9A)
None
 1.27A 4uckA-5lhvA:
undetectable		 4uckA-5lhvA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_1
(CDL2.2)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 12 LEU A  56
ILE A  22
GLU A 145
ALA A 138
LEU A  89
 None
 1.34A 5ienA-5lhvA:
undetectable		 5ienA-5lhvA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_A_SAMA501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 11 GLY A 213
SER A  65
VAL A  77
THR A  87
ALA A  21
 None
 1.04A 5o96A-5lhvA:
undetectable
5o96B-5lhvA:
undetectable		 5o96A-5lhvA:
20.23
5o96B-5lhvA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_B_BO2B201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 12 SER A 198
THR A  93
THR A  94
ALA A 216
THR A  73
 None
SO4  A 301 ( 2.9A)
None
None
None
 1.11A 6hwdV-5lhvA:
undetectable
6hwdb-5lhvA:
undetectable		 6hwdV-5lhvA:
18.00
6hwdb-5lhvA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_N_BO2N201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 12 SER A 198
THR A  93
THR A  94
ALA A 216
THR A  73
 None
SO4  A 301 ( 2.9A)
None
None
None
 1.11A 6hwdH-5lhvA:
undetectable
6hwdN-5lhvA:
undetectable		 6hwdH-5lhvA:
18.00
6hwdN-5lhvA:
19.66