SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5li4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_2
(PROTEIN (ADENOSINE
KINASE))		 5li4 TAIL SHEATH PROTEIN
(Staphylococcus
phage
812) 		3 / 3 LEU A  62
SER A  57
ASN A  81
 None
 0.84A 1bx4A-5li4A:
undetectable		 1bx4A-5li4A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_B_115B1_2
(HMG-COA REDUCTASE)		 5li4 TAIL SHEATH PROTEIN
(Staphylococcus
phage
812) 		4 / 8 ARG A 560
SER A 577
VAL A 579
ASN A 557
 None
 1.18A 1hwiB-5li4A:
undetectable		 1hwiB-5li4A:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_A_117A2_1
(HMG-COA REDUCTASE)		 5li4 TAIL SHEATH PROTEIN
(Staphylococcus
phage
812) 		4 / 8 ARG A 560
SER A 577
VAL A 579
ASN A 557
 None
 1.02A 1hwkA-5li4A:
undetectable		 1hwkA-5li4A:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_C_117C4_1
(HMG-COA REDUCTASE)		 5li4 TAIL SHEATH PROTEIN
(Staphylococcus
phage
812) 		4 / 8 ARG A 560
SER A 577
VAL A 579
ASN A 557
 None
 1.08A 1hwkC-5li4A:
undetectable		 1hwkC-5li4A:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_D_117D3_2
(HMG-COA REDUCTASE)		 5li4 TAIL SHEATH PROTEIN
(Staphylococcus
phage
812) 		4 / 8 ARG A 560
SER A 577
VAL A 579
ASN A 557
 None
 1.08A 1hwkD-5li4A:
undetectable		 1hwkD-5li4A:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5li4 TAIL SHEATH PROTEIN
(Staphylococcus
phage
812) 		4 / 7 GLN A 543
PHE A 545
LEU A 500
PHE A 499
 None
 0.75A 2dysP-5li4A:
undetectable
2dysW-5li4A:
undetectable		 2dysP-5li4A:
17.47
2dysW-5li4A:
8.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5li4 TAIL SHEATH PROTEIN
(Staphylococcus
phage
812) 		5 / 12 VAL A 437
VAL A 366
SER A 385
SER A 390
ASN A 455
 None
 1.30A 2y01B-5li4A:
undetectable		 2y01B-5li4A:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW5_A_TOPA208_1
(DIHYDROFOLATE
REDUCTASE)		 5li4 TAIL SHEATH PROTEIN
(Staphylococcus
phage
812) 		5 / 11 ASN A  81
LEU A  53
GLU A  46
VAL A 190
THR A  49
 None
 1.25A 3jw5A-5li4A:
undetectable		 3jw5A-5li4A:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_B_PZIB802_0
(GLUTAMATE RECEPTOR 2)		 5li4 TAIL SHEATH PROTEIN
(Staphylococcus
phage
812) 		3 / 3 SER A  78
ASP A 401
ASN A 406
 None
 0.99A 3lsfB-5li4A:
undetectable
3lsfE-5li4A:
undetectable		 3lsfB-5li4A:
20.04
3lsfE-5li4A:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_E_PZIE802_0
(GLUTAMATE RECEPTOR 2)		 5li4 TAIL SHEATH PROTEIN
(Staphylococcus
phage
812) 		3 / 3 ASP A 401
ASN A 406
SER A  78
 None
 0.99A 3lsfB-5li4A:
undetectable
3lsfE-5li4A:
undetectable		 3lsfB-5li4A:
20.04
3lsfE-5li4A:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_A_ACTA207_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 5li4 TAIL SHEATH PROTEIN
(Staphylococcus
phage
812) 		4 / 7 LEU A  74
ASP A 401
ARG A 404
ALA A  75
 None
 1.17A 3mbgA-5li4A:
undetectable
3mbgB-5li4A:
undetectable		 3mbgA-5li4A:
11.79
3mbgB-5li4A:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5li4 TAIL SHEATH PROTEIN
(Staphylococcus
phage
812) 		4 / 6 GLY A  40
ILE A  92
GLN A  41
VAL A 344
 None
 0.99A 4d39B-5li4A:
undetectable		 4d39B-5li4A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_ACTA803_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5li4 TAIL SHEATH PROTEIN
(Staphylococcus
phage
812) 		4 / 6 GLY A  40
ILE A  92
GLN A  41
VAL A 344
 None
 0.98A 4kcnA-5li4A:
undetectable		 4kcnA-5li4A:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_C_CHDC102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5li4 TAIL SHEATH PROTEIN
(Staphylococcus
phage
812) 		4 / 7 LEU A 533
ASN A 497
LEU A 500
LEU A 504
 None
 0.74A 4wg0B-5li4A:
undetectable
4wg0C-5li4A:
undetectable		 4wg0B-5li4A:
4.92
4wg0C-5li4A:
4.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_L_CHDL103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5li4 TAIL SHEATH PROTEIN
(Staphylococcus
phage
812) 		4 / 7 ASN A 497
LEU A 500
LEU A 504
LEU A 533
 None
 0.77A 4wg0L-5li4A:
undetectable
4wg0M-5li4A:
undetectable		 4wg0L-5li4A:
4.92
4wg0M-5li4A:
4.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GLM_A_ACTA613_0
(GLYCOSIDE HYDROLASE
FAMILY 43)		 5li4 TAIL SHEATH PROTEIN
(Staphylococcus
phage
812) 		3 / 3 ASP A 402
SER A  78
TYR A  82
 None
 0.91A 5glmA-5li4A:
undetectable		 5glmA-5li4A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_B_PFLB407_1
(PROTON-GATED ION
CHANNEL)		 5li4 TAIL SHEATH PROTEIN
(Staphylococcus
phage
812) 		4 / 7 ILE A 525
ILE A 524
THR A 517
ILE A 518
 None
 0.87A 5murB-5li4A:
undetectable		 5murB-5li4A:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TQR_B_SAMB8009_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EZH2, POLYCOMB
PROTEIN SUZ12)		 5li4 TAIL SHEATH PROTEIN
(Staphylococcus
phage
812) 		5 / 10 LEU A  88
CYH A  37
TYR A 334
VAL A 352
TYR A 333
 None
 1.18A 5tqrB-5li4A:
undetectable		 5tqrB-5li4A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		 5li4 TAIL SHEATH PROTEIN
(Staphylococcus
phage
812) 		5 / 12 VAL A 437
VAL A 366
SER A 385
SER A 390
ASN A 455
 None
 1.13A 6h7lA-5li4A:
undetectable		 6h7lA-5li4A:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 5li4 TAIL SHEATH PROTEIN
(Staphylococcus
phage
812) 		5 / 12 VAL A 437
VAL A 366
SER A 385
SER A 390
ASN A 455
 None
 1.13A 6h7lB-5li4A:
undetectable		 6h7lB-5li4A:
8.35