SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5lji'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BU5_A_RBFA301_1
(PROTEIN (FLAVODOXIN))		 5lji FLAVODOXIN
(Streptococcus
pneumoniae) 		6 / 7 THR A  12
ASN A  14
THR A  58
GLY A  91
ASP A  92
TYR A  95
 FMN  A 201 (-3.3A)
FMN  A 201 (-3.7A)
FMN  A 201 (-3.6A)
FMN  A 201 (-3.3A)
None
FMN  A 201 (-3.5A)
 0.55A 1bu5A-5ljiA:
23.7		 1bu5A-5ljiA:
32.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BU5_B_RBFB302_1
(PROTEIN (FLAVODOXIN))		 5lji FLAVODOXIN
(Streptococcus
pneumoniae) 		6 / 8 THR A  12
ASN A  14
THR A  58
GLY A  91
ASP A  92
TYR A  95
 FMN  A 201 (-3.3A)
FMN  A 201 (-3.7A)
FMN  A 201 (-3.6A)
FMN  A 201 (-3.3A)
None
FMN  A 201 (-3.5A)
 0.55A 1bu5B-5ljiA:
23.8		 1bu5B-5ljiA:
32.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_D_T3D602_1
(TRANSTHYRETIN)		 5lji FLAVODOXIN
(Streptococcus
pneumoniae) 		5 / 12 LYS A   5
ALA A  52
LEU A  80
ALA A  43
VAL A  41
 None
 1.09A 1sn5B-5ljiA:
undetectable
1sn5D-5ljiA:
undetectable		 1sn5B-5ljiA:
20.53
1sn5D-5ljiA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N3I_A_ROCA201_2
(PROTEASE)		 5lji FLAVODOXIN
(Streptococcus
pneumoniae) 		4 / 6 ILE A  18
ILE A  84
GLY A  86
VAL A  33
 None
 0.94A 3n3iA-5ljiA:
undetectable		 3n3iA-5ljiA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZV_B_ECNB411_1
(FLAVOHEMOGLOBIN)		 5lji FLAVODOXIN
(Streptococcus
pneumoniae) 		5 / 9 ILE A  84
ILE A  51
ALA A 139
LEU A 142
ALA A 114
 None
 1.10A 3ozvB-5ljiA:
3.8		 3ozvB-5ljiA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R75_A_BEZA701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 5lji FLAVODOXIN
(Streptococcus
pneumoniae) 		5 / 12 GLU A  67
SER A  10
GLY A  13
THR A  12
SER A  90
 None
FMN  A 201 (-2.5A)
FMN  A 201 (-4.1A)
FMN  A 201 (-3.3A)
FMN  A 201 (-2.8A)
 1.45A 3r75A-5ljiA:
undetectable		 3r75A-5ljiA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R75_A_BEZA701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 5lji FLAVODOXIN
(Streptococcus
pneumoniae) 		5 / 12 GLU A  67
SER A  10
THR A  12
SER A  90
THR A  15
 None
FMN  A 201 (-2.5A)
FMN  A 201 (-3.3A)
FMN  A 201 (-2.8A)
FMN  A 201 (-3.6A)
 1.48A 3r75A-5ljiA:
undetectable		 3r75A-5ljiA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R75_B_BEZB701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 5lji FLAVODOXIN
(Streptococcus
pneumoniae) 		5 / 12 GLU A  67
SER A  10
GLY A  13
THR A  12
SER A  90
 None
FMN  A 201 (-2.5A)
FMN  A 201 (-4.1A)
FMN  A 201 (-3.3A)
FMN  A 201 (-2.8A)
 1.45A 3r75B-5ljiA:
6.4		 3r75B-5ljiA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R75_B_BEZB701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 5lji FLAVODOXIN
(Streptococcus
pneumoniae) 		5 / 12 GLU A  67
SER A  10
THR A  12
SER A  90
THR A  15
 None
FMN  A 201 (-2.5A)
FMN  A 201 (-3.3A)
FMN  A 201 (-2.8A)
FMN  A 201 (-3.6A)
 1.49A 3r75B-5ljiA:
6.4		 3r75B-5ljiA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA CHAIN)		 5lji FLAVODOXIN
(Streptococcus
pneumoniae) 		3 / 3 SER A  90
ALA A  55
VAL A  54
 FMN  A 201 (-2.8A)
None
None
 0.55A 5xiwC-5ljiA:
3.5		 5xiwC-5ljiA:
22.15