SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ljy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_A_CHDA1150_0
(ALCOHOL
DEHYDROGENASE)		 5ljy ENVELOPMENT
POLYPROTEIN
(Hantaan
orthohantavirus) 		5 / 11 LEU A 375
HIS A 399
LEU A 343
LEU A 326
VAL A 373
 None
 1.31A 1ee2A-5ljyA:
undetectable		 1ee2A-5ljyA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_B_CHDB1250_1
(ALCOHOL
DEHYDROGENASE)		 5ljy ENVELOPMENT
POLYPROTEIN
(Hantaan
orthohantavirus) 		5 / 11 LEU A 375
HIS A 399
LEU A 343
LEU A 326
VAL A 373
 None
 1.29A 1ee2B-5ljyA:
undetectable		 1ee2B-5ljyA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_RALB600_2
(ESTROGEN RECEPTOR)		 5ljy ENVELOPMENT
POLYPROTEIN
(Hantaan
orthohantavirus) 		4 / 4 LEU A 349
THR A 350
ILE A 359
HIS A 399
 None
 1.25A 2jfaB-5ljyA:
undetectable		 2jfaB-5ljyA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_D_TC9D1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5ljy ENVELOPMENT
POLYPROTEIN
(Hantaan
orthohantavirus) 		4 / 8 THR A 188
ARG A 152
ILE A 151
ASP A 302
 None
 1.07A 2xytE-5ljyA:
undetectable		 2xytE-5ljyA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 5ljy ENVELOPMENT
POLYPROTEIN
(Hantaan
orthohantavirus) 		5 / 11 ILE A 304
ILE A 306
VAL A 308
LEU A  25
VAL A  19
 None
 0.93A 3w67A-5ljyA:
undetectable		 3w67A-5ljyA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DPD_A_SAMA601_0
(PROTEIN LYSINE
METHYLTRANSFERASE 1)		 5ljy ENVELOPMENT
POLYPROTEIN
(Hantaan
orthohantavirus) 		5 / 12 LEU A  27
ILE A  57
HIS A 180
VAL A 181
VAL A 183
 None
 1.16A 5dpdA-5ljyA:
undetectable		 5dpdA-5ljyA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_B_SALB203_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 5ljy ENVELOPMENT
POLYPROTEIN
(Hantaan
orthohantavirus) 		4 / 6 PRO A 224
GLY A 225
LEU A 199
VAL A 269
 None
 0.96A 5x80A-5ljyA:
undetectable
5x80B-5ljyA:
undetectable		 5x80A-5ljyA:
15.62
5x80B-5ljyA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IBL_A_H98A501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 5ljy SCFVA5
(Homo
sapiens) 		5 / 12 THR H  83
VAL H 111
VAL H 109
VAL H  67
TYR H  90
 None
 1.44A 6iblA-5ljyH:
undetectable		 6iblA-5ljyH:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IBL_B_H98B501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 5ljy SCFVA5
(Homo
sapiens) 		5 / 12 THR H  83
VAL H 111
VAL H 109
VAL H  67
TYR H  90
 None
 1.45A 6iblB-5ljyH:
undetectable		 6iblB-5ljyH:
18.91