SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5lk7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKY_A_DR7A100_2
(PROTEASE)
5lk7 VP1
(Slow
bee
paralysis
virus)
5 / 9 ASP A  35
ILE A 223
PRO A  92
VAL A  93
ILE A  94
None
1.28A 3ekyB-5lk7A:
undetectable
3ekyB-5lk7A:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HZN_G_ACTG225_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)
5lk7 VP1
(Slow
bee
paralysis
virus)
3 / 3 PRO A  14
LEU A  15
GLN A  11
None
0.66A 3hznG-5lk7A:
undetectable
3hznH-5lk7A:
undetectable
3hznG-5lk7A:
19.12
3hznH-5lk7A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9Q_A_9TPA601_1
(SERUM ALBUMIN)
5lk7 VP1
(Slow
bee
paralysis
virus)
5 / 12 TYR A 221
ILE A  91
TYR A  43
LEU A  72
GLY A  89
None
1.14A 4l9qA-5lk7A:
undetectable
4l9qA-5lk7A:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA303_1
(CHITOSANASE)
5lk7 VP1
(Slow
bee
paralysis
virus)
4 / 6 ILE A 139
GLY A 203
VAL A 120
HIS A 123
None
0.76A 4oltA-5lk7A:
undetectable
4oltA-5lk7A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB303_1
(CHITOSANASE)
5lk7 VP1
(Slow
bee
paralysis
virus)
4 / 6 ILE A 139
GLY A 203
VAL A 120
HIS A 123
None
0.74A 4oltB-5lk7A:
undetectable
4oltB-5lk7A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_D_SAMD301_0
(PUTATIVE
METHYLTRANSFERASE
BUD23)
5lk7 VP1
(Slow
bee
paralysis
virus)
5 / 12 TYR A 221
GLY A  89
MET A 238
ILE A  94
SER A  95
None
1.13A 4qtuD-5lk7A:
undetectable
4qtuD-5lk7A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVG_A_SAMA503_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)
5lk7 VP1
(Slow
bee
paralysis
virus)
5 / 12 ILE A 202
GLY A 203
ASN A  59
VAL A 118
ILE A 163
None
1.11A 4rvgA-5lk7A:
undetectable
4rvgA-5lk7A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_B_GMJB301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)
5lk7 VP1
(Slow
bee
paralysis
virus)
5 / 12 TYR A 221
LEU A 105
SER A  96
ILE A  91
LEU A  72
None
0.96A 6djzB-5lk7A:
undetectable
6djzB-5lk7A:
20.94