SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5lki'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GS4_A_ZK5A1918_1
(ANDROGEN RECEPTOR)		 5lki TCDA1
(Photorhabdus
luminescens) 		5 / 12 LEU A1889
GLY A  91
GLN A  95
VAL A1850
LEU A1963
 None
 1.02A 1gs4A-5lkiA:
undetectable		 1gs4A-5lkiA:
6.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_D_CCSD47_0
(GLUTATHIONE
S-TRANSFERASE)		 5lki TCDA1
(Photorhabdus
luminescens) 		4 / 7 LEU A2375
GLY A2369
LEU A2344
TYR A2341
 None
 0.90A 1gtiD-5lkiA:
undetectable		 1gtiD-5lkiA:
6.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_E_CCSE47_0
(GLUTATHIONE
S-TRANSFERASE)		 5lki TCDA1
(Photorhabdus
luminescens) 		4 / 7 LEU A2375
GLY A2369
LEU A2344
TYR A2341
 None
 0.89A 1gtiE-5lkiA:
undetectable		 1gtiE-5lkiA:
6.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_4
(HIV-1 PROTEASE)		 5lki TCDA1
(Photorhabdus
luminescens) 		4 / 4 GLY A2453
ASP A2428
GLY A2424
THR A2503
 None
 1.04A 1hxbB-5lkiA:
undetectable		 1hxbB-5lkiA:
3.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5lki TCDA1
(Photorhabdus
luminescens) 		5 / 11 TRP A1598
SER A1095
ARG A1301
ALA A1583
LEU A1584
 None
 1.47A 1jb0B-5lkiA:
undetectable		 1jb0B-5lkiA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_C_ADNC1503_1
(CLASS B ACID
PHOSPHATASE)		 5lki TCDA1
(Photorhabdus
luminescens) 		4 / 8 PHE A1110
TRP A1141
ASP A1127
TYR A1109
 None
 0.94A 1rmtC-5lkiA:
undetectable		 1rmtC-5lkiA:
6.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_D_ADND1504_1
(CLASS B ACID
PHOSPHATASE)		 5lki TCDA1
(Photorhabdus
luminescens) 		4 / 8 PHE A1110
TRP A1141
ASP A1127
TYR A1109
 None
 0.98A 1rmtD-5lkiA:
undetectable		 1rmtD-5lkiA:
6.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XP0_A_VDNA201_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 5lki TCDA1
(Photorhabdus
luminescens) 		5 / 10 LEU A1625
ILE A1621
VAL A1779
LEU A1061
PHE A1078
 None
 1.18A 1xp0A-5lkiA:
undetectable		 1xp0A-5lkiA:
9.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XPQ_A_SPMA924_1
(FMS1 PROTEIN)		 5lki TCDA1
(Photorhabdus
luminescens) 		5 / 11 ASP A1759
LEU A1082
PHE A1609
LEU A1613
TYR A1081
 None
 1.26A 1xpqA-5lkiA:
0.0		 1xpqA-5lkiA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XPQ_C_SPMC921_1
(FMS1 PROTEIN)		 5lki TCDA1
(Photorhabdus
luminescens) 		5 / 11 ASP A1759
LEU A1082
PHE A1609
LEU A1613
TYR A1081
 None
 1.33A 1xpqC-5lkiA:
undetectable		 1xpqC-5lkiA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_A_ADNA433_1
(ADENOSYLHOMOCYSTEINA
SE)		 5lki TCDA1
(Photorhabdus
luminescens) 		5 / 12 LEU A1613
THR A1607
GLU A1634
LEU A1766
GLY A1762
 None
 1.20A 1xwfA-5lkiA:
undetectable		 1xwfA-5lkiA:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_B_ADNB433_1
(ADENOSYLHOMOCYSTEINA
SE)		 5lki TCDA1
(Photorhabdus
luminescens) 		5 / 12 LEU A1613
THR A1607
GLU A1634
LEU A1766
GLY A1762
 None
 1.20A 1xwfB-5lkiA:
undetectable		 1xwfB-5lkiA:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_C_ADNC433_1
(ADENOSYLHOMOCYSTEINA
SE)		 5lki TCDA1
(Photorhabdus
luminescens) 		5 / 12 LEU A1613
THR A1607
GLU A1634
LEU A1766
GLY A1762
 None
 1.19A 1xwfC-5lkiA:
undetectable		 1xwfC-5lkiA:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_D_ADND433_1
(ADENOSYLHOMOCYSTEINA
SE)		 5lki TCDA1
(Photorhabdus
luminescens) 		5 / 12 LEU A1613
THR A1607
GLU A1634
LEU A1766
GLY A1762
 None
 1.20A 1xwfD-5lkiA:
undetectable		 1xwfD-5lkiA:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 5lki TCDA1
(Photorhabdus
luminescens) 		4 / 6 ALA A2389
TYR A2341
ILE A2507
ILE A2357
 None
 1.18A 2dcfA-5lkiA:
undetectable		 2dcfA-5lkiA:
9.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5lki TCDA1
(Photorhabdus
luminescens) 		4 / 5 ARG A1602
MET A1596
THR A1585
LEU A1584
 None
 1.24A 2eimJ-5lkiA:
undetectable		 2eimJ-5lkiA:
2.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5lki TCDA1
(Photorhabdus
luminescens) 		4 / 5 ARG A1602
MET A1596
THR A1585
LEU A1584
 None
 1.26A 2eimW-5lkiA:
undetectable		 2eimW-5lkiA:
2.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_C_AZZC1211_1
(DEOXYNUCLEOSIDE
KINASE)		 5lki TCDA1
(Photorhabdus
luminescens) 		5 / 12 ILE A2508
VAL A2450
LEU A2484
PHE A2486
ALA A2421
 None
 1.35A 2jj8C-5lkiA:
undetectable		 2jj8C-5lkiA:
6.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZ7_A_CA4A1_1
(ANDROGEN RECEPTOR)		 5lki TCDA1
(Photorhabdus
luminescens) 		5 / 12 LEU A1889
GLY A  91
GLN A  95
VAL A1850
LEU A1963
 None
 1.02A 2oz7A-5lkiA:
undetectable		 2oz7A-5lkiA:
6.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA2_0
(FERROCHELATASE)		 5lki TCDA1
(Photorhabdus
luminescens) 		4 / 8 ARG A2512
PRO A2420
VAL A2417
MET A2454
 None
 1.06A 2qd2A-5lkiA:
undetectable		 2qd2A-5lkiA:
9.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMQ_A_BEZA3_0
(PROTEIN NDRG2)		 5lki TCDA1
(Photorhabdus
luminescens) 		4 / 7 TYR A 136
ARG A 999
ARG A 141
HIS A 130
 None
 1.38A 2qmqA-5lkiA:
undetectable		 2qmqA-5lkiA:
7.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5lki TCDA1
(Photorhabdus
luminescens) 		4 / 6 GLY A2307
GLY A2028
GLN A2032
PHE A2265
 None
 1.04A 2qx6A-5lkiA:
undetectable
2qx6B-5lkiA:
undetectable		 2qx6A-5lkiA:
6.99
2qx6B-5lkiA:
6.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UZ2_A_ACTA1123_0
(XENAVIDIN)		 5lki TCDA1
(Photorhabdus
luminescens) 		4 / 7 ASN A2374
SER A2390
TYR A1982
THR A2483
 None
 1.18A 2uz2A-5lkiA:
undetectable		 2uz2A-5lkiA:
4.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UZ2_A_ACTA1123_0
(XENAVIDIN)		 5lki TCDA1
(Photorhabdus
luminescens) 		4 / 7 LEU A1949
SER A 110
THR A 108
VAL A 104
 None
 1.14A 2uz2A-5lkiA:
undetectable		 2uz2A-5lkiA:
4.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XNR_A_ACTA1001_0
(NUCLEAR
POLYADENYLATED
RNA-BINDING PROTEIN
3)		 5lki TCDA1
(Photorhabdus
luminescens) 		3 / 3 SER A1014
ARG A1015
GLN A1105
 None
 0.88A 2xnrA-5lkiA:
undetectable		 2xnrA-5lkiA:
2.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM7_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 5lki TCDA1
(Photorhabdus
luminescens) 		4 / 7 ALA A2389
TYR A2341
ILE A2507
ILE A2357
 None
 1.19A 2zm7A-5lkiA:
undetectable		 2zm7A-5lkiA:
9.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5lki TCDA1
(Photorhabdus
luminescens) 		4 / 7 PHE A1136
ARG A1602
MET A1596
THR A1585
 None
 1.13A 2zxwN-5lkiA:
5.5
2zxwW-5lkiA:
1.4		 2zxwN-5lkiA:
11.55
2zxwW-5lkiA:
2.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5lki TCDA1
(Photorhabdus
luminescens) 		4 / 5 ILE A1045
TYR A1773
MET A1777
THR A1775
 None
 1.46A 3abkN-5lkiA:
2.6
3abkW-5lkiA:
undetectable		 3abkN-5lkiA:
11.55
3abkW-5lkiA:
2.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 5lki TCDA1
(Photorhabdus
luminescens) 		4 / 5 ARG A1602
MET A1596
THR A1585
LEU A1584
 None
 1.28A 3ag1J-5lkiA:
1.5		 3ag1J-5lkiA:
2.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 5lki TCDA1
(Photorhabdus
luminescens) 		4 / 5 ARG A1602
MET A1596
THR A1585
LEU A1584
 None
 1.18A 3ag2J-5lkiA:
1.5		 3ag2J-5lkiA:
2.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 5lki TCDA1
(Photorhabdus
luminescens) 		4 / 5 ARG A1602
MET A1596
THR A1585
LEU A1584
 None
 1.17A 3ag4J-5lkiA:
1.5		 3ag4J-5lkiA:
2.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_2
(HIV-1 PROTEASE)		 5lki TCDA1
(Photorhabdus
luminescens) 		4 / 4 GLY A2453
ASP A2428
GLY A2424
THR A2503
 None
 1.05A 3k4vC-5lkiA:
undetectable		 3k4vC-5lkiA:
3.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L4D_D_TPFD490_1
(STEROL 14-ALPHA
DEMETHYLASE)		 5lki TCDA1
(Photorhabdus
luminescens) 		4 / 8 ALA A1994
ALA A1998
THR A2002
LEU A2009
 None
 0.99A 3l4dD-5lkiA:
2.9		 3l4dD-5lkiA:
10.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5lki TCDA1
(Photorhabdus
luminescens) 		5 / 11 TRP A1598
SER A1095
ARG A1301
ALA A1583
LEU A1584
 None
 1.47A 3pcqB-5lkiA:
undetectable		 3pcqB-5lkiA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3M_A_DLUA398_1
(PFV INTEGRASE)		 5lki TCDA1
(Photorhabdus
luminescens) 		5 / 8 ASP A1759
GLY A1762
PRO A1757
GLN A1633
GLU A1756
 None
 1.37A 3s3mA-5lkiA:
undetectable		 3s3mA-5lkiA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3N_A_DLUA398_1
(PFV INTEGRASE)		 5lki TCDA1
(Photorhabdus
luminescens) 		5 / 8 ASP A1759
GLY A1762
PRO A1757
GLN A1633
GLU A1756
 None
 1.40A 3s3nA-5lkiA:
undetectable		 3s3nA-5lkiA:
9.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3N_A_DLUA398_1
(PFV INTEGRASE)		 5lki TCDA1
(Photorhabdus
luminescens) 		4 / 8 ASP A2382
GLY A1978
PRO A2487
GLN A2497
 None
 1.03A 3s3nA-5lkiA:
undetectable		 3s3nA-5lkiA:
9.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_A_SAMA500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 5lki TCDA1
(Photorhabdus
luminescens) 		3 / 3 HIS A1808
SER A1626
GLU A1628
 None
 0.92A 3s8pA-5lkiA:
undetectable		 3s8pA-5lkiA:
7.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_B_SAMB500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 5lki TCDA1
(Photorhabdus
luminescens) 		3 / 3 HIS A1128
SER A1014
ASN A1304
 None
 0.91A 3s8pB-5lkiA:
undetectable		 3s8pB-5lkiA:
7.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_3
(NS3 PROTEASE, NS4A
PROTEIN)		 5lki TCDA1
(Photorhabdus
luminescens) 		4 / 5 SER A1035
PRO A1041
TYR A1044
VAL A1840
 None
 1.34A 3sufC-5lkiA:
undetectable		 3sufC-5lkiA:
6.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1Y_A_RBFA1176_1
(PUTATIVE PROTEASE I)		 5lki TCDA1
(Photorhabdus
luminescens) 		4 / 8 GLN A1293
ASN A1289
GLN A1292
THR A1580
 None
 1.36A 4d1yA-5lkiA:
undetectable
4d1yB-5lkiA:
undetectable		 4d1yA-5lkiA:
5.68
4d1yB-5lkiA:
5.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB6_C_VLBC503_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		 5lki TCDA1
(Photorhabdus
luminescens) 		5 / 12 ASP A2456
PRO A2487
ILE A2415
VAL A2417
ILE A2507
 None
 1.29A 4eb6B-5lkiA:
undetectable
4eb6C-5lkiA:
undetectable		 4eb6B-5lkiA:
10.52
4eb6C-5lkiA:
10.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I1N_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5lki TCDA1
(Photorhabdus
luminescens) 		5 / 11 ILE A1621
LEU A1082
PHE A1078
LEU A1060
THR A1623
 None
 1.29A 4i1nA-5lkiA:
undetectable		 4i1nA-5lkiA:
5.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KT0_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5lki TCDA1
(Photorhabdus
luminescens) 		5 / 9 TRP A1598
SER A1095
ARG A1301
ALA A1583
LEU A1584
 None
 1.47A 4kt0B-5lkiA:
0.0		 4kt0B-5lkiA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L3G_F_ACTF401_0
(METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN)		 5lki TCDA1
(Photorhabdus
luminescens) 		3 / 3 ARG A2027
LEU A2023
GLU A2024
 None
 0.58A 4l3gF-5lkiA:
6.5		 4l3gF-5lkiA:
9.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_2_PQN22002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5lki TCDA1
(Photorhabdus
luminescens) 		5 / 9 TRP A1598
SER A1095
ARG A1301
ALA A1583
LEU A1584
 None
 1.46A 4l6v2-5lkiA:
0.0		 4l6v2-5lkiA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5lki TCDA1
(Photorhabdus
luminescens) 		5 / 9 TRP A1598
SER A1095
ARG A1301
ALA A1583
LEU A1584
 None
 1.43A 4l6vB-5lkiA:
0.0		 4l6vB-5lkiA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		 5lki TCDA1
(Photorhabdus
luminescens) 		4 / 7 PRO A1723
VAL A1747
ALA A1643
PHE A1641
 None
 1.11A 4lb2A-5lkiA:
undetectable		 4lb2A-5lkiA:
13.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_2
(GLUCOCORTICOID
RECEPTOR)		 5lki TCDA1
(Photorhabdus
luminescens) 		3 / 3 LEU A1608
MET A1758
TYR A1595
 None
 0.94A 4p6xG-5lkiA:
undetectable		 4p6xG-5lkiA:
7.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 5lki TCDA1
(Photorhabdus
luminescens) 		3 / 3 PRO A1776
MET A1777
TYR A1773
 None
 0.95A 4qa0B-5lkiA:
undetectable		 4qa0B-5lkiA:
9.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 5lki TCDA1
(Photorhabdus
luminescens) 		3 / 3 PRO A1776
MET A1777
TYR A1773
 None
 0.93A 4qa0A-5lkiA:
undetectable		 4qa0A-5lkiA:
9.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 5lki TCDA1
(Photorhabdus
luminescens) 		3 / 3 PRO A1776
MET A1777
TYR A1773
 None
 0.87A 4qa2B-5lkiA:
undetectable		 4qa2B-5lkiA:
9.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RKU_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5lki TCDA1
(Photorhabdus
luminescens) 		5 / 9 TRP A1598
SER A1095
ARG A1301
ALA A1583
LEU A1584
 None
 1.48A 4rkuB-5lkiA:
0.0		 4rkuB-5lkiA:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5lki TCDA1
(Photorhabdus
luminescens) 		5 / 10 TRP A1598
SER A1095
ARG A1301
ALA A1583
LEU A1584
 None
 1.44A 4xk8B-5lkiA:
undetectable		 4xk8B-5lkiA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y28_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5lki TCDA1
(Photorhabdus
luminescens) 		5 / 9 TRP A1598
SER A1095
ARG A1301
ALA A1583
LEU A1584
 None
 1.47A 4y28B-5lkiA:
0.0		 4y28B-5lkiA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_1
(THYROXINE-BINDING
GLOBULIN)		 5lki TCDA1
(Photorhabdus
luminescens) 		5 / 10 SER A1095
LEU A1200
LEU A1198
LEU A1234
LEU A1267
 None
 0.96A 4yiaA-5lkiA:
undetectable		 4yiaA-5lkiA:
9.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDZ_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5lki TCDA1
(Photorhabdus
luminescens) 		4 / 7 ILE A  90
PHE A  96
THR A1852
MET A1846
 None
 0.93A 4zdzA-5lkiA:
undetectable		 4zdzA-5lkiA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CPR_B_SAMB402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 5lki TCDA1
(Photorhabdus
luminescens) 		3 / 3 HIS A1128
SER A1014
ASN A1304
 None
 0.88A 5cprB-5lkiA:
undetectable		 5cprB-5lkiA:
7.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CR1_A_T44A201_1
(TRANSTHYRETIN)		 5lki TCDA1
(Photorhabdus
luminescens) 		4 / 5 LEU A2433
ALA A2431
LEU A2448
VAL A2429
 None
 1.20A 5cr1A-5lkiA:
undetectable		 5cr1A-5lkiA:
3.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5lki TCDA1
(Photorhabdus
luminescens) 		4 / 4 LEU A1586
TYR A1235
PRO A1160
ILE A1111
 None
 1.15A 5esgA-5lkiA:
undetectable		 5esgA-5lkiA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWK_F_EVPF102_1
(DNA TOPOISOMERASE
2-ALPHA)		 5lki TCDA1
(Photorhabdus
luminescens) 		4 / 5 GLY A1864
ASP A1865
ARG A1966
MET A1854
 None
 1.43A 5gwkA-5lkiA:
4.6		 5gwkA-5lkiA:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H8T_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 5lki TCDA1
(Photorhabdus
luminescens) 		5 / 12 TYR A2341
LEU A2353
ILE A2511
ILE A2507
LEU A2396
 None
 1.12A 5h8tA-5lkiA:
2.0		 5h8tA-5lkiA:
4.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA301_1
(CHITOSANASE)		 5lki TCDA1
(Photorhabdus
luminescens) 		4 / 8 ILE A2475
GLY A2436
THR A2481
LEU A1983
 None
 1.04A 5hwaA-5lkiA:
1.3		 5hwaA-5lkiA:
7.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGZ_A_SPRA404_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 5lki TCDA1
(Photorhabdus
luminescens) 		5 / 9 LEU A2433
ILE A2507
ILE A2412
GLU A2473
PHE A2472
 None
 1.29A 5igzA-5lkiA:
undetectable		 5igzA-5lkiA:
8.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 5lki TCDA1
(Photorhabdus
luminescens) 		5 / 12 THR A1054
GLU A1143
PHE A1110
ALA A1096
ILE A1203
 None
 1.21A 5iwuA-5lkiA:
3.1		 5iwuA-5lkiA:
8.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5lki TCDA1
(Photorhabdus
luminescens) 		5 / 7 PHE A1136
ARG A1602
MET A1596
THR A1585
LEU A1584
 None
 1.32A 5iy5N-5lkiA:
4.4
5iy5W-5lkiA:
1.4		 5iy5N-5lkiA:
11.55
5iy5W-5lkiA:
2.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JHD_J_EDTJ301_0
(TCRBETA CHAIN)		 5lki TCDA1
(Photorhabdus
luminescens) 		4 / 5 TYR A1122
LYS A1146
GLY A1119
SER A1114
 None
 1.14A 5jhdJ-5lkiA:
3.1		 5jhdJ-5lkiA:
7.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KM8_B_L8PB201_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 2,
MITOCHONDRIAL)		 5lki TCDA1
(Photorhabdus
luminescens) 		4 / 8 GLN A2195
ALA A2092
GLN A2093
SER A2094
 None
 1.15A 5km8A-5lkiA:
undetectable
5km8B-5lkiA:
undetectable		 5km8A-5lkiA:
5.27
5km8B-5lkiA:
5.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8R_B_PQNB841_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5lki TCDA1
(Photorhabdus
luminescens) 		5 / 9 TRP A1598
SER A1095
ARG A1301
ALA A1583
LEU A1584
 None
 1.41A 5l8rB-5lkiA:
0.1		 5l8rB-5lkiA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5lki TCDA1
(Photorhabdus
luminescens) 		4 / 5 ARG A1602
MET A1596
THR A1585
LEU A1584
 None
 1.31A 5wauJ-5lkiA:
undetectable		 5wauJ-5lkiA:
2.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5lki TCDA1
(Photorhabdus
luminescens) 		4 / 5 ARG A1602
MET A1596
THR A1585
LEU A1584
 None
 1.18A 5x1bW-5lkiA:
1.5		 5x1bW-5lkiA:
2.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5lki TCDA1
(Photorhabdus
luminescens) 		4 / 5 ARG A1602
MET A1596
THR A1585
LEU A1584
 None
 1.23A 5x1fW-5lkiA:
undetectable		 5x1fW-5lkiA:
2.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_A_ACTA403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 5lki TCDA1
(Photorhabdus
luminescens) 		3 / 3 TYR A 968
ASP A 966
GLN A 969
 None
 0.83A 6g1pA-5lkiA:
undetectable		 6g1pA-5lkiA:
8.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5lki TCDA1
(Photorhabdus
luminescens) 		4 / 6 GLY A2037
LEU A2040
VAL A2270
PHE A2263
 None
 0.89A 6h7lB-5lkiA:
undetectable		 6h7lB-5lkiA:
3.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5lki TCDA1
(Photorhabdus
luminescens) 		4 / 5 ARG A1602
MET A1596
THR A1585
LEU A1584
 None
 1.23A 6nknJ-5lkiA:
1.4		 6nknJ-5lkiA:
2.12