SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ll1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_B_CQAB401_0
(HISTAMINE
N-METHYLTRANSFERASE)		 5ll1 URICASE
(Danio
rerio) 		4 / 7 GLY A  17
PRO A  62
ASP A  64
THR A  69
 None
 1.03A 2aouB-5ll1A:
undetectable		 2aouB-5ll1A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGZ_D_COCD401_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5ll1 URICASE
(Danio
rerio) 		4 / 6 TRP A 192
TYR A 189
GLN A 237
ILE A 250
 None
 1.27A 2pgzD-5ll1A:
undetectable
2pgzE-5ll1A:
undetectable		 2pgzD-5ll1A:
20.60
2pgzE-5ll1A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ll1 URICASE
(Danio
rerio) 		4 / 7 ARG A 134
VAL A 208
TRP A 192
GLU A 246
 None
 1.07A 3jx3A-5ll1A:
undetectable
3jx3B-5ll1A:
undetectable		 3jx3A-5ll1A:
19.71
3jx3B-5ll1A:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 5ll1 URICASE
(Danio
rerio) 		4 / 7 ARG A 134
VAL A 208
TRP A 192
GLU A 246
 None
 1.11A 3n5vA-5ll1A:
undetectable
3n5vB-5ll1A:
undetectable		 3n5vA-5ll1A:
18.97
3n5vB-5ll1A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 5ll1 URICASE
(Danio
rerio) 		4 / 7 ARG A 134
VAL A 208
TRP A 192
GLU A 246
 None
 1.07A 3n5yA-5ll1A:
undetectable
3n5yB-5ll1A:
undetectable		 3n5yA-5ll1A:
18.97
3n5yB-5ll1A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3N_A_DLUA398_1
(PFV INTEGRASE)		 5ll1 URICASE
(Danio
rerio) 		4 / 8 GLY A 288
TYR A 189
PRO A 255
GLN A 257
 None
 1.03A 3s3nA-5ll1A:
undetectable		 3s3nA-5ll1A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_H_ZPCH1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5ll1 URICASE
(Danio
rerio) 		4 / 7 GLU A  83
ILE A  82
VAL A 188
PHE A 135
 None
 0.86A 4a97H-5ll1A:
undetectable		 4a97H-5ll1A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_B_H4BB1720_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ll1 URICASE
(Danio
rerio) 		4 / 7 TRP A 192
GLU A 246
ARG A 134
VAL A 208
 None
 1.04A 4ctwA-5ll1A:
undetectable
4ctwB-5ll1A:
undetectable		 4ctwA-5ll1A:
18.97
4ctwB-5ll1A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ll1 URICASE
(Danio
rerio) 		4 / 7 ARG A 134
VAL A 208
TRP A 192
GLU A 246
 None
 1.05A 4jsfA-5ll1A:
undetectable
4jsfB-5ll1A:
undetectable		 4jsfA-5ll1A:
18.97
4jsfB-5ll1A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_D_ILED602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5ll1 URICASE
(Danio
rerio) 		4 / 6 ILE A 107
ALA A  74
VAL A  70
HIS A  25
 None
 0.90A 5eclD-5ll1A:
undetectable		 5eclD-5ll1A:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ll1 URICASE
(Danio
rerio) 		4 / 6 ARG A 134
VAL A 208
TRP A 192
GLU A 246
 None
 1.08A 5unvA-5ll1A:
undetectable
5unvB-5ll1A:
undetectable		 5unvA-5ll1A:
18.97
5unvB-5ll1A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ll1 URICASE
(Danio
rerio) 		4 / 7 ARG A 134
VAL A 208
TRP A 192
GLU A 246
 None
 1.10A 5vujA-5ll1A:
undetectable
5vujB-5ll1A:
undetectable		 5vujA-5ll1A:
18.97
5vujB-5ll1A:
18.97