SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5llb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_A_9CRA165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 5llb POLYPHOSPHATE KINASE
2
(Francisella
tularensis) 		5 / 12 PHE C  58
ILE C  70
LEU C  77
ALA C 235
ILE C 239
 None
 1.01A 1epbA-5llbC:
undetectable		 1epbA-5llbC:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKZ_A_ZMRA469_2
(NEURAMINIDASE)		 5llb POLYPHOSPHATE KINASE
2
(Francisella
tularensis) 		4 / 6 ASP C 226
ARG C 174
ILE C 260
ARG C 230
 None
 1.41A 3ckzA-5llbC:
undetectable		 3ckzA-5llbC:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_A_0LIA1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 5llb POLYPHOSPHATE KINASE
2
(Francisella
tularensis) 		5 / 9 ILE C  85
ILE C  57
ILE C  56
MET C  74
ILE C 159
 None
 1.01A 3zosA-5llbC:
undetectable		 3zosA-5llbC:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_ACTA605_0
(SERUM ALBUMIN)		 5llb POLYPHOSPHATE KINASE
2
(Francisella
tularensis) 		4 / 6 TYR C 103
GLU C 127
ARG C 123
ASN C 122
 None
6YZ  C 303 ( 4.0A)
None
6YZ  C 303 (-3.4A)
 0.92A 4zbqA-5llbC:
undetectable		 4zbqA-5llbC:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJC_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 5llb POLYPHOSPHATE KINASE
2
(Francisella
tularensis) 		5 / 12 PHE C  43
LEU C 115
LEU C  40
TYR C 238
ILE C 160
 None
 1.24A 5ljcA-5llbC:
undetectable		 5ljcA-5llbC:
16.54