SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5lm2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3B_B_FOLB401_1
(DIHYDROFOLATE
REDUCTASE)		 5lm2 TYROSINE-PROTEIN
PHOSPHATASE
NON-RECEPTOR TYPE 23
(Homo
sapiens) 		3 / 3 GLU A 306
GLN A 313
ARG A 316
 None
 0.90A 2w3bB-5lm2A:
undetectable		 2w3bB-5lm2A:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA502_0
(RNA POLYMERASE
3D-POL)		 5lm2 TYROSINE-PROTEIN
PHOSPHATASE
NON-RECEPTOR TYPE 23
(Homo
sapiens) 		3 / 3 ARG A 210
LYS A  26
LYS A  30
 None
 1.16A 4k50A-5lm2A:
undetectable		 4k50A-5lm2A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_E_ACTE502_0
(RNA POLYMERASE
3D-POL)		 5lm2 TYROSINE-PROTEIN
PHOSPHATASE
NON-RECEPTOR TYPE 23
(Homo
sapiens) 		3 / 3 ARG A 210
LYS A  26
LYS A  30
 None
 1.10A 4k50E-5lm2A:
undetectable		 4k50E-5lm2A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI506_0
(RNA POLYMERASE
3D-POL)		 5lm2 TYROSINE-PROTEIN
PHOSPHATASE
NON-RECEPTOR TYPE 23
(Homo
sapiens) 		3 / 3 ARG A 210
LYS A  26
LYS A  30
 None
 1.11A 4k50I-5lm2A:
undetectable		 4k50I-5lm2A:
21.94