SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5lm9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NMU_F_SAMF228_0 (FIBRILLARIN-LIKE RRNA/TRNA 2'-O-METHYLTRANSFERA SE NOP5/NOP56 RELATED PROTEIN)	5lm9	TRANSCRIPTION TERMINATION/ANTITERM INATION PROTEIN NUSA (Escherichia coli)	5 / 12	GLU A 335 LYS A 347 SER A 329 ALA A 281 ASP A 306	None MG A 506 ( 4.8A) None None MG A 506 (-4.0A)	1.29A	3nmuA-5lm9A: 2.7 3nmuF-5lm9A: undetectable	3nmuA-5lm9A: 22.05 3nmuF-5lm9A: 22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NY4_A_SMXA309_1 (BETA-LACTAMASE)	5lm9	TRANSCRIPTION TERMINATION/ANTITERM INATION PROTEIN NUSA (Escherichia coli)	4 / 5	ILE A 137 ARG A 228 GLU A 171 GLU A 269	None	1.39A	3ny4A-5lm9A: undetectable	3ny4A-5lm9A: 22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M51_A_BEZA501_0 (AMIDOHYDROLASE FAMILY PROTEIN)	5lm9	TRANSCRIPTION TERMINATION/ANTITERM INATION PROTEIN NUSA (Escherichia coli)	4 / 6	ILE A 273 SER A 263 PHE A 209 LEU A 205	None	0.97A	4m51A-5lm9A: undetectable	4m51A-5lm9A: 22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5O96_E_SAME501_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE E)	5lm9	TRANSCRIPTION TERMINATION/ANTITERM INATION PROTEIN NUSA (Escherichia coli)	5 / 9	PRO A 169 GLY A 268 SER A 200 ARG A 233 GLN A 323	None None None SO4 A 503 ( 4.6A) None	1.30A	5o96E-5lm9A: undetectable 5o96F-5lm9A: undetectable	5o96E-5lm9A: 22.49 5o96F-5lm9A: 22.49

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3NMU_F_SAMF228_0","FIBRILLARIN-LIKE RRNA\/TRNA 2'-O-METHYLTRANSFERASE;NOP5\/NOP56 RELATED PROTEIN","5lm9","TRANSCRIPTION TERMINATION\/ANTITERMINATION PROTEIN NUSA","Escherichia coli",5,"GLU A 335;LYS A 347;SER A 329;ALA A 281;ASP A 306","None; MG A 506 ( 4.8A);None;None; MG A 506 (-4.0A)","1.29A","3nmuA-5lm9A:2.7;3nmuF-5lm9A:undetectable","3nmuA-5lm9A:22.05;3nmuF-5lm9A:22.81"],["3NY4_A_SMXA309_1","BETA-LACTAMASE","5lm9","TRANSCRIPTION TERMINATION\/ANTITERMINATION PROTEIN NUSA","Escherichia coli",4,"ILE A 137;ARG A 228;GLU A 171;GLU A 269","None","1.39A","3ny4A-5lm9A:undetectable","3ny4A-5lm9A:22.26"],["4M51_A_BEZA501_0","AMIDOHYDROLASE FAMILY PROTEIN","5lm9","TRANSCRIPTION TERMINATION\/ANTITERMINATION PROTEIN NUSA","Escherichia coli",4,"ILE A 273;SER A 263;PHE A 209;LEU A 205","None","0.97A","4m51A-5lm9A:undetectable","4m51A-5lm9A:22.65"],["5O96_E_SAME501_0","RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE E","5lm9","TRANSCRIPTION TERMINATION\/ANTITERMINATION PROTEIN NUSA","Escherichia coli",5,"PRO A 169;GLY A 268;SER A 200;ARG A 233;GLN A 323","None;None;None;SO4 A 503 ( 4.6A);None","1.30A","5o96E-5lm9A:undetectable;5o96F-5lm9A:undetectable","5o96E-5lm9A:22.49;5o96F-5lm9A:22.49"]]