SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5lmc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_D_DCFD1853_1
(ADENOSINE DEAMINASE)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 12 HIS A 227
HIS A  84
GLU A  81
HIS A  79
ASP A 166
 FEO  A 501 ( 3.3A)
FEO  A 501 (-3.2A)
FEO  A 501 (-3.1A)
FEO  A 501 (-3.3A)
FEO  A 501 ( 2.5A)
 1.35A 1a4lD-5lmcA:
undetectable		 1a4lD-5lmcA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_D_PPFD412_1
(PHOSPHONOACETATE
HYDROLASE)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		4 / 8 ASP A 166
HIS A  79
HIS A  84
HIS A 147
 FEO  A 501 ( 2.5A)
FEO  A 501 (-3.3A)
FEO  A 501 (-3.2A)
FEO  A 501 ( 3.4A)
 0.87A 1ei6D-5lmcA:
undetectable		 1ei6D-5lmcA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_CCSB381_0
(ESTROGEN RECEPTOR)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		3 / 3 GLU A  82
ALA A  80
SER A 109
 None
 0.52A 1errB-5lmcA:
undetectable		 1errB-5lmcA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FML_A_RTLA401_0
(RETINOL DEHYDRATASE)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 12 TYR A 101
LEU A 138
LEU A 130
HIS A  84
ILE A  40
 None
None
None
FEO  A 501 (-3.2A)
None
 1.19A 1fmlA-5lmcA:
undetectable		 1fmlA-5lmcA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FML_B_RTLB501_0
(RETINOL DEHYDRATASE)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 12 TYR A 101
LEU A 138
LEU A 130
HIS A  84
ILE A  40
 None
None
None
FEO  A 501 (-3.2A)
None
 1.19A 1fmlB-5lmcA:
2.6		 1fmlB-5lmcA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.44A 1gtfP-5lmcA:
undetectable
1gtfQ-5lmcA:
undetectable		 1gtfP-5lmcA:
10.86
1gtfQ-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.42A 1gtfT-5lmcA:
undetectable
1gtfU-5lmcA:
undetectable		 1gtfT-5lmcA:
10.86
1gtfU-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_N_TRPN81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.41A 1utdN-5lmcA:
undetectable
1utdO-5lmcA:
undetectable		 1utdN-5lmcA:
10.86
1utdO-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_R_TRPR81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.45A 1utdR-5lmcA:
undetectable
1utdS-5lmcA:
undetectable		 1utdR-5lmcA:
10.86
1utdS-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		4 / 7 PHE A 365
ARG A 253
THR A 300
LEU A 299
 None
 0.94A 2eikA-5lmcA:
undetectable
2eikJ-5lmcA:
undetectable		 2eikA-5lmcA:
20.94
2eikJ-5lmcA:
8.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_B_AZZB1211_1
(DEOXYNUCLEOSIDE
KINASE)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 12 LEU A 326
PHE A 257
VAL A 310
ALA A 340
PHE A 365
 None
 1.45A 2jj8B-5lmcA:
2.1		 2jj8B-5lmcA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0J_B_BEZB500_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 11 ASP A  83
HIS A  84
HIS A 147
ASP A 166
HIS A 227
 FEO  A 501 ( 2.5A)
FEO  A 501 (-3.2A)
FEO  A 501 ( 3.4A)
FEO  A 501 ( 2.5A)
FEO  A 501 ( 3.3A)
 0.78A 2q0jB-5lmcA:
19.6		 2q0jB-5lmcA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WM3_A_NFLA1301_1
(NMRA-LIKE FAMILY
DOMAIN CONTAINING
PROTEIN 1)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		4 / 6 LEU A 138
PHE A 163
LEU A 162
ASP A 159
 None
 1.09A 2wm3A-5lmcA:
undetectable		 2wm3A-5lmcA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1161_1
(ALLERGEN ARG R 1)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		4 / 5 VAL A  76
TYR A 101
VAL A 124
ASP A 128
 None
 1.33A 2x45C-5lmcA:
undetectable		 2x45C-5lmcA:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_B_ACHB1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		4 / 7 VAL A 229
TYR A 194
CYH A 191
ILE A 238
 None
 1.29A 2xz5B-5lmcA:
undetectable
2xz5E-5lmcA:
undetectable		 2xz5B-5lmcA:
19.22
2xz5E-5lmcA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_C_ACHC1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		4 / 8 ILE A 238
VAL A 229
TYR A 194
CYH A 191
 None
 1.24A 2xz5A-5lmcA:
undetectable
2xz5C-5lmcA:
undetectable		 2xz5A-5lmcA:
19.22
2xz5C-5lmcA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_D_ACHD1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		4 / 8 ILE A 238
VAL A 229
TYR A 194
CYH A 191
 None
 1.26A 2xz5C-5lmcA:
undetectable
2xz5D-5lmcA:
undetectable		 2xz5C-5lmcA:
19.22
2xz5D-5lmcA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_E_ACHE1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		4 / 7 ILE A 238
VAL A 229
TYR A 194
CYH A 191
 None
 1.25A 2xz5D-5lmcA:
undetectable
2xz5E-5lmcA:
undetectable		 2xz5D-5lmcA:
19.22
2xz5E-5lmcA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		4 / 8 PHE A 365
ARG A 253
THR A 300
LEU A 299
 None
 0.88A 3ag3N-5lmcA:
undetectable
3ag3W-5lmcA:
undetectable		 3ag3N-5lmcA:
20.94
3ag3W-5lmcA:
8.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOD_A_HQEA1173_1
(FMN-BINDING PROTEIN)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		4 / 7 HIS A  23
ASP A  52
HIS A 171
HIS A  53
 PO4  A 503 ( 4.2A)
None
PO4  A 503 (-4.5A)
ACY  A 506 (-4.1A)
 1.35A 3zodA-5lmcA:
undetectable		 3zodA-5lmcA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		4 / 8 ILE A  72
ASP A  71
ILE A  67
VAL A  12
 None
 0.78A 4acaC-5lmcA:
7.7		 4acaC-5lmcA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		4 / 8 ILE A  72
ASP A  71
ILE A  67
VAL A  12
 None
 0.80A 4acbC-5lmcA:
4.4		 4acbC-5lmcA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C2P_A_X8ZA709_1
(ANGIOTENSIN-CONVERTI
NG ENZYME)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 11 HIS A 171
HIS A  23
GLU A  81
HIS A 227
TYR A  35
 PO4  A 503 (-4.5A)
PO4  A 503 ( 4.2A)
FEO  A 501 (-3.1A)
FEO  A 501 ( 3.3A)
None
 1.46A 4c2pA-5lmcA:
undetectable		 4c2pA-5lmcA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_A_ADNA501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		4 / 5 GLN A 190
THR A  29
HIS A 147
LEU A 199
 None
None
FEO  A 501 ( 3.4A)
None
 1.02A 4lvcA-5lmcA:
5.3		 4lvcA-5lmcA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_C_ADNC501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		4 / 5 GLN A 190
THR A  29
HIS A 147
LEU A 199
 None
None
FEO  A 501 ( 3.4A)
None
 1.03A 4lvcC-5lmcA:
undetectable		 4lvcC-5lmcA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.43A 5eeuG-5lmcA:
undetectable
5eeuH-5lmcA:
undetectable		 5eeuG-5lmcA:
10.86
5eeuH-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.47A 5eeuN-5lmcA:
undetectable
5eeuO-5lmcA:
undetectable		 5eeuN-5lmcA:
10.86
5eeuO-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.40A 5eeuP-5lmcA:
undetectable
5eeuQ-5lmcA:
undetectable		 5eeuP-5lmcA:
10.86
5eeuQ-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.42A 5eeuR-5lmcA:
undetectable
5eeuS-5lmcA:
undetectable		 5eeuR-5lmcA:
10.86
5eeuS-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.40A 5eeuT-5lmcA:
undetectable
5eeuU-5lmcA:
undetectable		 5eeuT-5lmcA:
10.86
5eeuU-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.43A 5eeuU-5lmcA:
undetectable
5eeuV-5lmcA:
undetectable		 5eeuU-5lmcA:
10.86
5eeuV-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.43A 5eevG-5lmcA:
undetectable
5eevH-5lmcA:
undetectable		 5eevG-5lmcA:
10.86
5eevH-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.47A 5eevN-5lmcA:
undetectable
5eevO-5lmcA:
undetectable		 5eevN-5lmcA:
10.86
5eevO-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.40A 5eevP-5lmcA:
undetectable
5eevQ-5lmcA:
undetectable		 5eevP-5lmcA:
10.86
5eevQ-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.42A 5eevR-5lmcA:
undetectable
5eevS-5lmcA:
undetectable		 5eevR-5lmcA:
10.86
5eevS-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.39A 5eevT-5lmcA:
undetectable
5eevU-5lmcA:
undetectable		 5eevT-5lmcA:
10.86
5eevU-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.43A 5eewG-5lmcA:
undetectable
5eewH-5lmcA:
undetectable		 5eewG-5lmcA:
10.86
5eewH-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.47A 5eewN-5lmcA:
undetectable
5eewO-5lmcA:
undetectable		 5eewN-5lmcA:
10.86
5eewO-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.40A 5eewP-5lmcA:
undetectable
5eewQ-5lmcA:
undetectable		 5eewP-5lmcA:
10.86
5eewQ-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.42A 5eewR-5lmcA:
undetectable
5eewS-5lmcA:
undetectable		 5eewR-5lmcA:
10.86
5eewS-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.39A 5eewT-5lmcA:
undetectable
5eewU-5lmcA:
undetectable		 5eewT-5lmcA:
10.86
5eewU-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.43A 5eexG-5lmcA:
undetectable
5eexH-5lmcA:
undetectable		 5eexG-5lmcA:
10.86
5eexH-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.38A 5eexA-5lmcA:
undetectable
5eexK-5lmcA:
undetectable		 5eexA-5lmcA:
10.86
5eexK-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.47A 5eexN-5lmcA:
undetectable
5eexO-5lmcA:
undetectable		 5eexN-5lmcA:
10.86
5eexO-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.40A 5eexP-5lmcA:
undetectable
5eexQ-5lmcA:
undetectable		 5eexP-5lmcA:
10.86
5eexQ-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.42A 5eexR-5lmcA:
undetectable
5eexS-5lmcA:
undetectable		 5eexR-5lmcA:
10.86
5eexS-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.39A 5eexT-5lmcA:
undetectable
5eexU-5lmcA:
undetectable		 5eexT-5lmcA:
10.86
5eexU-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.43A 5eeyG-5lmcA:
undetectable
5eeyH-5lmcA:
undetectable		 5eeyG-5lmcA:
10.86
5eeyH-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.47A 5eeyN-5lmcA:
undetectable
5eeyO-5lmcA:
undetectable		 5eeyN-5lmcA:
10.86
5eeyO-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.40A 5eeyP-5lmcA:
undetectable
5eeyQ-5lmcA:
undetectable		 5eeyP-5lmcA:
10.86
5eeyQ-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.42A 5eeyR-5lmcA:
undetectable
5eeyS-5lmcA:
undetectable		 5eeyR-5lmcA:
10.86
5eeyS-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.39A 5eeyT-5lmcA:
undetectable
5eeyU-5lmcA:
undetectable		 5eeyT-5lmcA:
10.86
5eeyU-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.43A 5eezG-5lmcA:
undetectable
5eezH-5lmcA:
undetectable		 5eezG-5lmcA:
10.86
5eezH-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.47A 5eezN-5lmcA:
undetectable
5eezO-5lmcA:
undetectable		 5eezN-5lmcA:
10.86
5eezO-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.40A 5eezP-5lmcA:
undetectable
5eezQ-5lmcA:
undetectable		 5eezP-5lmcA:
10.86
5eezQ-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.43A 5eezR-5lmcA:
undetectable
5eezS-5lmcA:
undetectable		 5eezR-5lmcA:
10.86
5eezS-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.39A 5eezT-5lmcA:
undetectable
5eezU-5lmcA:
undetectable		 5eezT-5lmcA:
10.86
5eezU-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.43A 5ef0G-5lmcA:
undetectable
5ef0H-5lmcA:
undetectable		 5ef0G-5lmcA:
10.86
5ef0H-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.38A 5ef0A-5lmcA:
undetectable
5ef0K-5lmcA:
undetectable		 5ef0A-5lmcA:
10.86
5ef0K-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.47A 5ef0N-5lmcA:
undetectable
5ef0O-5lmcA:
undetectable		 5ef0N-5lmcA:
10.86
5ef0O-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.40A 5ef0P-5lmcA:
undetectable
5ef0Q-5lmcA:
undetectable		 5ef0P-5lmcA:
10.86
5ef0Q-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.42A 5ef0R-5lmcA:
undetectable
5ef0S-5lmcA:
undetectable		 5ef0R-5lmcA:
10.86
5ef0S-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.40A 5ef0T-5lmcA:
undetectable
5ef0U-5lmcA:
undetectable		 5ef0T-5lmcA:
10.86
5ef0U-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.43A 5ef1G-5lmcA:
undetectable
5ef1H-5lmcA:
undetectable		 5ef1G-5lmcA:
10.86
5ef1H-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.47A 5ef1N-5lmcA:
undetectable
5ef1O-5lmcA:
undetectable		 5ef1N-5lmcA:
10.86
5ef1O-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.39A 5ef1P-5lmcA:
undetectable
5ef1Q-5lmcA:
undetectable		 5ef1P-5lmcA:
10.86
5ef1Q-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.43A 5ef1R-5lmcA:
undetectable
5ef1S-5lmcA:
undetectable		 5ef1R-5lmcA:
10.86
5ef1S-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.39A 5ef1T-5lmcA:
undetectable
5ef1U-5lmcA:
undetectable		 5ef1T-5lmcA:
10.86
5ef1U-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.43A 5ef2G-5lmcA:
undetectable
5ef2H-5lmcA:
undetectable		 5ef2G-5lmcA:
10.86
5ef2H-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.47A 5ef2N-5lmcA:
undetectable
5ef2O-5lmcA:
undetectable		 5ef2N-5lmcA:
10.86
5ef2O-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.40A 5ef2P-5lmcA:
undetectable
5ef2Q-5lmcA:
undetectable		 5ef2P-5lmcA:
10.86
5ef2Q-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.43A 5ef2R-5lmcA:
undetectable
5ef2S-5lmcA:
undetectable		 5ef2R-5lmcA:
10.86
5ef2S-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.39A 5ef2T-5lmcA:
undetectable
5ef2U-5lmcA:
undetectable		 5ef2T-5lmcA:
10.86
5ef2U-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.43A 5ef3G-5lmcA:
undetectable
5ef3H-5lmcA:
undetectable		 5ef3G-5lmcA:
10.86
5ef3H-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.38A 5ef3A-5lmcA:
undetectable
5ef3K-5lmcA:
undetectable		 5ef3A-5lmcA:
10.86
5ef3K-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.47A 5ef3N-5lmcA:
undetectable
5ef3O-5lmcA:
undetectable		 5ef3N-5lmcA:
10.86
5ef3O-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.40A 5ef3P-5lmcA:
undetectable
5ef3Q-5lmcA:
undetectable		 5ef3P-5lmcA:
10.86
5ef3Q-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.42A 5ef3R-5lmcA:
undetectable
5ef3S-5lmcA:
undetectable		 5ef3R-5lmcA:
10.86
5ef3S-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 114
HIS A 113
ALA A 106
HIS A 116
ILE A  77
 None
 1.39A 5ef3T-5lmcA:
undetectable
5ef3U-5lmcA:
undetectable		 5ef3T-5lmcA:
10.86
5ef3U-5lmcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EVY_X_SALX502_1
(SALICYLATE
HYDROXYLASE)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		4 / 5 SER A  37
MET A  92
LEU A  91
PHE A  59
 None
 1.23A 5evyX-5lmcA:
3.1		 5evyX-5lmcA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_0
(TUBULIN BETA-2B
CHAIN)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 11 GLN A 170
ASN A  36
ASP A  83
TYR A 194
LEU A 199
 None
None
FEO  A 501 ( 2.5A)
None
None
 1.48A 5jh7B-5lmcA:
5.1		 5jh7B-5lmcA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5K_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		4 / 5 ILE A 198
GLU A  81
HIS A  84
HIS A 227
 PO4  A 503 (-4.6A)
FEO  A 501 (-3.1A)
FEO  A 501 (-3.2A)
FEO  A 501 ( 3.3A)
 1.00A 5n5kA-5lmcA:
2.4		 5n5kA-5lmcA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_A_ACTA301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 6 ASP A 166
HIS A  84
HIS A 227
HIS A 147
HIS A  23
 FEO  A 501 ( 2.5A)
FEO  A 501 (-3.2A)
FEO  A 501 ( 3.3A)
FEO  A 501 ( 3.4A)
PO4  A 503 ( 4.2A)
 1.20A 5ncdA-5lmcA:
undetectable
5ncdD-5lmcA:
undetectable		 5ncdA-5lmcA:
19.42
5ncdD-5lmcA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_A_ACTA301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 6 ASP A 166
HIS A 227
HIS A 171
HIS A 147
HIS A  23
 FEO  A 501 ( 2.5A)
FEO  A 501 ( 3.3A)
PO4  A 503 (-4.5A)
FEO  A 501 ( 3.4A)
PO4  A 503 ( 4.2A)
 1.13A 5ncdA-5lmcA:
undetectable
5ncdD-5lmcA:
undetectable		 5ncdA-5lmcA:
19.42
5ncdD-5lmcA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_C_ACTC301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 6 HIS A  23
ASP A 166
HIS A  84
HIS A 227
HIS A 147
 PO4  A 503 ( 4.2A)
FEO  A 501 ( 2.5A)
FEO  A 501 (-3.2A)
FEO  A 501 ( 3.3A)
FEO  A 501 ( 3.4A)
 1.22A 5ncdB-5lmcA:
undetectable
5ncdC-5lmcA:
undetectable		 5ncdB-5lmcA:
19.42
5ncdC-5lmcA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_C_ACTC301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 6 HIS A  23
ASP A 166
HIS A 227
HIS A 171
HIS A 147
 PO4  A 503 ( 4.2A)
FEO  A 501 ( 2.5A)
FEO  A 501 ( 3.3A)
PO4  A 503 (-4.5A)
FEO  A 501 ( 3.4A)
 1.15A 5ncdB-5lmcA:
undetectable
5ncdC-5lmcA:
undetectable		 5ncdB-5lmcA:
19.42
5ncdC-5lmcA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_B_AZMB302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		4 / 8 ASP A 166
HIS A  84
HIS A 227
HIS A 147
 FEO  A 501 ( 2.5A)
FEO  A 501 (-3.2A)
FEO  A 501 ( 3.3A)
FEO  A 501 ( 3.4A)
 0.94A 5nekB-5lmcA:
undetectable		 5nekB-5lmcA:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_B_AZMB302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		4 / 8 ASP A 166
HIS A 147
HIS A  79
HIS A 227
 FEO  A 501 ( 2.5A)
FEO  A 501 ( 3.4A)
FEO  A 501 (-3.3A)
FEO  A 501 ( 3.3A)
 1.00A 5nekB-5lmcA:
undetectable		 5nekB-5lmcA:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_A_ACTA302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 6 ASP A 166
HIS A  84
HIS A 227
HIS A 147
HIS A  23
 FEO  A 501 ( 2.5A)
FEO  A 501 (-3.2A)
FEO  A 501 ( 3.3A)
FEO  A 501 ( 3.4A)
PO4  A 503 ( 4.2A)
 1.19A 5nelA-5lmcA:
undetectable
5nelD-5lmcA:
undetectable		 5nelA-5lmcA:
19.42
5nelD-5lmcA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_A_ACTA302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 6 ASP A 166
HIS A 227
HIS A 171
HIS A 147
HIS A  23
 FEO  A 501 ( 2.5A)
FEO  A 501 ( 3.3A)
PO4  A 503 (-4.5A)
FEO  A 501 ( 3.4A)
PO4  A 503 ( 4.2A)
 1.11A 5nelA-5lmcA:
undetectable
5nelD-5lmcA:
undetectable		 5nelA-5lmcA:
19.42
5nelD-5lmcA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_C_ACTC302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 6 HIS A  23
ASP A 166
HIS A 227
HIS A 171
HIS A 147
 PO4  A 503 ( 4.2A)
FEO  A 501 ( 2.5A)
FEO  A 501 ( 3.3A)
PO4  A 503 (-4.5A)
FEO  A 501 ( 3.4A)
 1.19A 5nelB-5lmcA:
undetectable
5nelC-5lmcA:
undetectable		 5nelB-5lmcA:
19.42
5nelC-5lmcA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWU_A_ACAA18_1
(WTFP-TAG,GP41)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 12 ALA A 324
GLY A 325
LYS A 322
GLU A 297
LEU A 299
 None
 1.16A 5nwuA-5lmcA:
undetectable		 5nwuA-5lmcA:
5.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZ0_A_ZLDA301_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR ETHR)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 12 GLY A 389
ILE A 392
VAL A 285
LEU A 369
TRP A 396
 None
 1.29A 5nz0A-5lmcA:
undetectable		 5nz0A-5lmcA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TJZ_A_BEZA302_0
(4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		3 / 3 MET A 319
GLU A 328
ARG A 359
 None
 1.09A 5tjzA-5lmcA:
6.1		 5tjzA-5lmcA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 ILE A   9
ASN A   7
LYS A 136
ILE A 139
LEU A 218
 None
 1.43A 5vkqA-5lmcA:
undetectable
5vkqB-5lmcA:
undetectable		 5vkqA-5lmcA:
14.74
5vkqB-5lmcA:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 10 ILE A   9
ASN A   7
LYS A 136
ILE A 139
LEU A 218
 None
 1.43A 5vkqC-5lmcA:
undetectable
5vkqD-5lmcA:
undetectable		 5vkqC-5lmcA:
14.74
5vkqD-5lmcA:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y80_A_IREA402_0
(CYCLIN-G-ASSOCIATED
KINASE)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 11 ALA A 224
ASP A 166
SER A 226
ILE A  77
ASN A  78
 None
FEO  A 501 ( 2.5A)
FEO  A 501 ( 4.3A)
None
None
 1.34A 5y80A-5lmcA:
undetectable		 5y80A-5lmcA:
9.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 11 HIS A  23
ILE A 198
HIS A 147
HIS A 227
HIS A 171
 PO4  A 503 ( 4.2A)
PO4  A 503 (-4.6A)
FEO  A 501 ( 3.4A)
FEO  A 501 ( 3.3A)
PO4  A 503 (-4.5A)
 1.37A 5z0fA-5lmcA:
undetectable
5z0fB-5lmcA:
undetectable		 5z0fA-5lmcA:
10.30
5z0fB-5lmcA:
9.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ESM_A_PZEA307_1
(MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		3 / 3 TYR A  35
HIS A 227
PHE A  22
 None
FEO  A 501 ( 3.3A)
PO4  A 503 ( 4.9A)
 1.03A 6esmA-5lmcA:
2.6		 6esmA-5lmcA:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_A_ADNA501_2
(-)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		4 / 5 GLN A 190
THR A  29
HIS A 147
LEU A 199
 None
None
FEO  A 501 ( 3.4A)
None
 1.03A 6gbnA-5lmcA:
5.0		 6gbnA-5lmcA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_D_ADND501_2
(-)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		4 / 5 GLN A 190
THR A  29
HIS A 147
LEU A 199
 None
None
FEO  A 501 ( 3.4A)
None
 1.02A 6gbnD-5lmcA:
5.0		 6gbnD-5lmcA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCO_A_FY5A1003_0
(ATP-BINDING CASSETTE
SUB-FAMILY G MEMBER
2)		 5lmc ANAEROBIC NITRIC
OXIDE REDUCTASE
FLAVORUBREDOXIN
(Escherichia
coli) 		5 / 11 ASN A   7
VAL A  46
THR A 154
PHE A 163
VAL A 161
 None
 1.42A 6hcoA-5lmcA:
undetectable
6hcoB-5lmcA:
undetectable		 6hcoA-5lmcA:
21.21
6hcoB-5lmcA:
21.21