SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ln1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXK_A_IMNA2001_1
(SERUM ALBUMIN)		 5ln1 26S PROTEASOME
REGULATORY SUBUNIT
RPN10
(Saccharomyces
cerevisiae) 		4 / 8 SER A  63
PHE A  65
ALA A   5
LEU A  98
 None
 1.12A 2bxkA-5ln1A:
undetectable		 2bxkA-5ln1A:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_A_J01A1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 5ln1 26S PROTEASOME
REGULATORY SUBUNIT
RPN10
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  93
ALA A  94
ALA A 112
THR A  89
LEU A 128
 None
 1.14A 2japA-5ln1A:
4.6		 2japA-5ln1A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_B_J01B1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 5ln1 26S PROTEASOME
REGULATORY SUBUNIT
RPN10
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  93
ALA A  94
ALA A 112
THR A  89
LEU A 128
 None
 1.15A 2japB-5ln1A:
5.5		 2japB-5ln1A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X7H_A_PFNA1374_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 5ln1 26S PROTEASOME
REGULATORY SUBUNIT
RPN10
(Saccharomyces
cerevisiae) 		4 / 6 PRO A 117
SER A 116
GLU A  14
TYR A  15
 None
 1.50A 2x7hA-5ln1A:
2.8		 2x7hA-5ln1A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 5ln1 26S PROTEASOME
REGULATORY SUBUNIT
RPN10
(Saccharomyces
cerevisiae) 		5 / 12 SER A 116
VAL A  33
ASP A  11
ILE A  10
ASN A  12
 None
 1.46A 3jayA-5ln1A:
undetectable		 3jayA-5ln1A:
11.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 5ln1 26S PROTEASOME
REGULATORY SUBUNIT
RPN10
(Saccharomyces
cerevisiae) 		5 / 12 GLU A  68
GLY A  75
PHE A  37
ILE A  10
ARG A  41
 None
 1.10A 4hytA-5ln1A:
4.1		 4hytA-5ln1A:
12.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_C_OBNC2004_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 5ln1 26S PROTEASOME
REGULATORY SUBUNIT
RPN10
(Saccharomyces
cerevisiae) 		5 / 12 GLU A  68
GLY A  75
PHE A  37
ILE A  10
ARG A  41
 None
 1.12A 4hytC-5ln1A:
undetectable		 4hytC-5ln1A:
12.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 5ln1 26S PROTEASOME
REGULATORY SUBUNIT
RPN10
(Saccharomyces
cerevisiae) 		4 / 7 ASN A  12
GLU A  82
GLU A  14
TYR A  15
 None
 1.34A 4mj8C-5ln1A:
undetectable		 4mj8C-5ln1A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_I_SPMI202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 5ln1 26S PROTEASOME
REGULATORY SUBUNIT
RPN10
(Saccharomyces
cerevisiae) 		4 / 7 ASN A  12
GLU A  82
GLU A  14
TYR A  15
 None
 1.33A 4r87I-5ln1A:
undetectable		 4r87I-5ln1A:
22.75