SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5lnb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Y_B_MK1B524_1
(PROTEIN (PROTEASE))		 5lnb UBIQUITIN-LIKE-SPECI
FIC PROTEASE 2
(Saccharomyces
cerevisiae) 		5 / 11 LEU B 166
VAL B 118
ILE B  66
THR B 133
ILE B 131
 None
 0.82A 1c6yA-5lnbB:
undetectable		 1c6yA-5lnbB:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_C_TFPC208_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5lnb UBIQUITIN-LIKE-SPECI
FIC PROTEASE 2
(Saccharomyces
cerevisiae) 		4 / 5 PHE B 185
LEU B 135
PHE B  87
MET B  83
 None
 1.04A 1wrlC-5lnbB:
undetectable		 1wrlC-5lnbB:
11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_E_TFPE212_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5lnb UBIQUITIN-LIKE-SPECI
FIC PROTEASE 2
(Saccharomyces
cerevisiae) 		4 / 7 PHE B 185
LEU B 135
PHE B  87
MET B  83
 None
 1.06A 1wrlE-5lnbB:
undetectable		 1wrlE-5lnbB:
11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_D_ACTD36_0
(GCN4 LEUCINE ZIPPER)		 5lnb UBIQUITIN-LIKE-SPECI
FIC PROTEASE 2
(Saccharomyces
cerevisiae) 		3 / 3 SER B 124
TYR B 125
HIS B 126
 None
ACT  B 901 (-3.2A)
None
 0.64A 2r2vD-5lnbB:
1.3		 2r2vD-5lnbB:
9.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_C_TFPC202_1
(PROTEIN S100-A4)		 5lnb UBIQUITIN-LIKE-SPECI
FIC PROTEASE 2
(Saccharomyces
cerevisiae) 		5 / 11 ASP B  59
LEU B  91
PHE B 185
ILE B 182
CYH B 130
 None
 1.38A 3ko0A-5lnbB:
undetectable
3ko0B-5lnbB:
undetectable
3ko0C-5lnbB:
undetectable
3ko0D-5lnbB:
undetectable		 3ko0A-5lnbB:
16.50
3ko0B-5lnbB:
16.50
3ko0C-5lnbB:
16.50
3ko0D-5lnbB:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD202_1
(PROTEIN S100-A4)		 5lnb UBIQUITIN-LIKE-SPECI
FIC PROTEASE 2
(Saccharomyces
cerevisiae) 		5 / 11 LEU B  91
PHE B 185
ILE B 182
CYH B 130
ASP B  59
 None
 1.41A 3ko0C-5lnbB:
undetectable
3ko0D-5lnbB:
undetectable
3ko0E-5lnbB:
undetectable
3ko0F-5lnbB:
undetectable		 3ko0C-5lnbB:
16.50
3ko0D-5lnbB:
16.50
3ko0E-5lnbB:
16.50
3ko0F-5lnbB:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_E_TFPE202_1
(PROTEIN S100-A4)		 5lnb UBIQUITIN-LIKE-SPECI
FIC PROTEASE 2
(Saccharomyces
cerevisiae) 		5 / 11 ASP B  59
LEU B  91
PHE B 185
ILE B 182
CYH B 130
 None
 1.41A 3ko0C-5lnbB:
undetectable
3ko0D-5lnbB:
undetectable
3ko0E-5lnbB:
undetectable
3ko0F-5lnbB:
undetectable		 3ko0C-5lnbB:
16.50
3ko0D-5lnbB:
16.50
3ko0E-5lnbB:
16.50
3ko0F-5lnbB:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_H_TFPH202_1
(PROTEIN S100-A4)		 5lnb UBIQUITIN-LIKE-SPECI
FIC PROTEASE 2
(Saccharomyces
cerevisiae) 		5 / 12 LEU B  91
PHE B 185
ILE B 182
CYH B 130
ASP B  59
 None
 1.39A 3ko0G-5lnbB:
undetectable
3ko0H-5lnbB:
undetectable
3ko0I-5lnbB:
undetectable
3ko0J-5lnbB:
undetectable		 3ko0G-5lnbB:
16.50
3ko0H-5lnbB:
16.50
3ko0I-5lnbB:
16.50
3ko0J-5lnbB:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_N_TFPN202_1
(PROTEIN S100-A4)		 5lnb UBIQUITIN-LIKE-SPECI
FIC PROTEASE 2
(Saccharomyces
cerevisiae) 		5 / 11 ASP B  59
LEU B  91
PHE B 185
ILE B 182
CYH B 130
 None
 1.38A 3ko0K-5lnbB:
undetectable
3ko0L-5lnbB:
undetectable
3ko0M-5lnbB:
undetectable
3ko0N-5lnbB:
undetectable		 3ko0K-5lnbB:
16.50
3ko0L-5lnbB:
16.50
3ko0M-5lnbB:
16.50
3ko0N-5lnbB:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO202_1
(PROTEIN S100-A4)		 5lnb UBIQUITIN-LIKE-SPECI
FIC PROTEASE 2
(Saccharomyces
cerevisiae) 		5 / 11 LEU B  91
PHE B 185
ILE B 182
CYH B 130
ASP B  59
 None
 1.39A 3ko0O-5lnbB:
undetectable
3ko0P-5lnbB:
undetectable
3ko0Q-5lnbB:
undetectable
3ko0R-5lnbB:
undetectable		 3ko0O-5lnbB:
16.50
3ko0P-5lnbB:
16.50
3ko0Q-5lnbB:
16.50
3ko0R-5lnbB:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_T_TFPT202_1
(PROTEIN S100-A4)		 5lnb UBIQUITIN-LIKE-SPECI
FIC PROTEASE 2
(Saccharomyces
cerevisiae) 		5 / 11 ASP B  59
LEU B  91
PHE B 185
ILE B 182
CYH B 130
 None
 1.41A 3ko0Q-5lnbB:
undetectable
3ko0R-5lnbB:
undetectable
3ko0S-5lnbB:
undetectable
3ko0T-5lnbB:
undetectable		 3ko0Q-5lnbB:
16.50
3ko0R-5lnbB:
16.50
3ko0S-5lnbB:
16.50
3ko0T-5lnbB:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 5lnb UBIQUITIN-LIKE-SPECI
FIC PROTEASE 2
(Saccharomyces
cerevisiae) 		4 / 8 ASN B 291
GLU B 290
TYR B 293
TYR B  29
 None
 1.13A 4mj8A-5lnbB:
undetectable
4mj8C-5lnbB:
2.7		 4mj8A-5lnbB:
21.33
4mj8C-5lnbB:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_B_017B101_1
(PROTEASE)		 5lnb UBIQUITIN-LIKE-SPECI
FIC PROTEASE 2
(Saccharomyces
cerevisiae) 		5 / 11 LEU B 166
VAL B 118
ILE B  66
THR B 133
ILE B 131
 None
 0.93A 4njtA-5lnbB:
undetectable		 4njtA-5lnbB:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_B_478B101_1
(HIV-1 PROTEASE)		 5lnb UBIQUITIN-LIKE-SPECI
FIC PROTEASE 2
(Saccharomyces
cerevisiae) 		5 / 11 LEU B 166
VAL B 118
ILE B  66
THR B 133
ILE B 131
 None
 0.98A 4rvjA-5lnbB:
undetectable		 4rvjA-5lnbB:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_D_478D101_1
(HIV-1 PROTEASE)		 5lnb UBIQUITIN-LIKE-SPECI
FIC PROTEASE 2
(Saccharomyces
cerevisiae) 		5 / 11 LEU B 166
VAL B 118
ILE B  66
THR B 133
ILE B 131
 None
 0.97A 4rvjC-5lnbB:
undetectable		 4rvjC-5lnbB:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 5lnb UBIQUITIN-LIKE-SPECI
FIC PROTEASE 2
(Saccharomyces
cerevisiae) 		3 / 3 ALA B 268
ASN B 271
LEU B 272
 None
 0.42A 5i1oC-5lnbB:
undetectable		 5i1oC-5lnbB:
8.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 5lnb UBIQUITIN-LIKE-SPECI
FIC PROTEASE 2
(Saccharomyces
cerevisiae) 		3 / 3 ALA B 268
ASN B 271
LEU B 272
 None
 0.38A 5i1pA-5lnbB:
undetectable		 5i1pA-5lnbB:
8.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA606_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 5lnb UBIQUITIN-LIKE-SPECI
FIC PROTEASE 2
(Saccharomyces
cerevisiae) 		4 / 5 GLU B 178
ASP B 169
HIS B 126
THR B 167
 None
 1.42A 6b58A-5lnbB:
undetectable		 6b58A-5lnbB:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_2
(-)		 5lnb UBIQUITIN-LIKE-SPECI
FIC PROTEASE 2
(Saccharomyces
cerevisiae) 		4 / 8 VAL B 240
TYR B 259
ASN B 226
CYH B 130
 None
 0.95A 6gneB-5lnbB:
undetectable		 6gneB-5lnbB:
18.85