SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5lnc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)		 5lnc VACUOLAR TRANSPORTER
CHAPERONE 4,CORE
HISTONE MACRO-H2A.1
(Homo
sapiens;
Saccharomyces
cerevisiae) 		4 / 6 CYH A 274
THR A 217
ASN A 275
GLY A 257
 None
 1.36A 3w9tE-5lncA:
undetectable		 3w9tE-5lncA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P68_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 5lnc VACUOLAR TRANSPORTER
CHAPERONE 4,CORE
HISTONE MACRO-H2A.1
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 ILE A 328
PHE A 309
SER A 342
ILE A 344
ILE A 332
 None
 1.33A 4p68A-5lncA:
undetectable		 4p68A-5lncA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_A_SAMA304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 5lnc VACUOLAR TRANSPORTER
CHAPERONE 4,CORE
HISTONE MACRO-H2A.1
(Saccharomyces
cerevisiae;
Homo
sapiens) 		5 / 12 GLY A 313
GLY A 315
ASP A 353
SER A 356
ALA A 325
 None
 1.03A 5l0zA-5lncA:
undetectable		 5l0zA-5lncA:
22.58