SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5lng'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXH_B_PACB1001_0
(PENICILLIN ACYLASE)		 5lng PUTATIVE FML
FIMBRIAL ADHESIN
FMLD
(Escherichia
coli) 		4 / 7 MET A 130
PHE A 144
PHE A   1
ILE A  40
 None
 0.79A 1fxhA-5lngA:
undetectable
1fxhB-5lngA:
undetectable		 1fxhA-5lngA:
23.85
1fxhB-5lngA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HVY_B_D16B415_1
(THYMIDYLATE SYNTHASE)		 5lng PUTATIVE FML
FIMBRIAL ADHESIN
FMLD
(Escherichia
coli) 		5 / 12 ILE A  55
ASN A  77
ASP A  96
GLY A  95
MET A 100
 None
 1.30A 1hvyB-5lngA:
undetectable		 1hvyB-5lngA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HVY_C_D16C416_1
(THYMIDYLATE SYNTHASE)		 5lng PUTATIVE FML
FIMBRIAL ADHESIN
FMLD
(Escherichia
coli) 		5 / 11 ILE A  55
ASN A  77
ASP A  96
GLY A  95
MET A 100
 None
 1.24A 1hvyC-5lngA:
undetectable		 1hvyC-5lngA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PNL_B_PACB559_0
(PENICILLIN
AMIDOHYDROLASE)		 5lng PUTATIVE FML
FIMBRIAL ADHESIN
FMLD
(Escherichia
coli) 		4 / 8 MET A 130
PHE A 144
PHE A   1
ILE A  40
 None
 0.84A 1pnlA-5lngA:
undetectable
1pnlB-5lngA:
undetectable		 1pnlA-5lngA:
23.85
1pnlB-5lngA:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_A_C2FA314_0
(UNCHARACTERIZED
PROTEIN)		 5lng PUTATIVE FML
FIMBRIAL ADHESIN
FMLD
(Escherichia
coli) 		5 / 12 VAL A 117
GLY A 116
ILE A  26
LEU A  67
ILE A 108
 None
 1.09A 3ijdA-5lngA:
undetectable		 3ijdA-5lngA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_0
(UNCHARACTERIZED
PROTEIN)		 5lng PUTATIVE FML
FIMBRIAL ADHESIN
FMLD
(Escherichia
coli) 		5 / 12 VAL A 117
GLY A 116
ILE A  26
LEU A  67
ILE A 108
 None
 1.14A 3ijdB-5lngA:
undetectable		 3ijdB-5lngA:
21.81