SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5lol'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_B_ADNB1502_1
(CLASS B ACID
PHOSPHATASE)		 5lol GLUTATHIONE
S-TRANSFERASE DHAR2
(Arabidopsis
thaliana) 		4 / 7 PHE A 141
TYR A 183
LEU A 187
THR A 148
 None
 1.10A 1rmtB-5lolA:
undetectable		 1rmtB-5lolA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_D_ADND1504_1
(CLASS B ACID
PHOSPHATASE)		 5lol GLUTATHIONE
S-TRANSFERASE DHAR2
(Arabidopsis
thaliana) 		4 / 8 PHE A 141
TYR A 183
LEU A 187
THR A 148
 None
 1.04A 1rmtD-5lolA:
undetectable		 1rmtD-5lolA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_A_STRA604_1
(CYTOCHROME P450
21-HYDROXYLASE)		 5lol GLUTATHIONE
S-TRANSFERASE DHAR2
(Arabidopsis
thaliana) 		5 / 12 VAL A 173
ILE A 102
GLY A  99
VAL A 142
LEU A 134
 None
 0.92A 4y8wA-5lolA:
undetectable		 4y8wA-5lolA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_B_STRB603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 5lol GLUTATHIONE
S-TRANSFERASE DHAR2
(Arabidopsis
thaliana) 		5 / 12 VAL A 173
ILE A 102
GLY A  99
VAL A 142
LEU A 134
 None
 0.93A 4y8wB-5lolA:
undetectable		 4y8wB-5lolA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 5lol GLUTATHIONE
S-TRANSFERASE DHAR2
(Arabidopsis
thaliana) 		5 / 12 VAL A 173
ILE A 102
GLY A  99
VAL A 142
LEU A 134
 None
 0.94A 4y8wC-5lolA:
undetectable		 4y8wC-5lolA:
18.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D9W_A_ASCA301_0
(DEHYDROASCORBATE
REDUCTASE)		 5lol GLUTATHIONE
S-TRANSFERASE DHAR2
(Arabidopsis
thaliana) 		5 / 9 PRO A  21
PHE A 103
HIS A 160
GLY A 206
TRP A 207
 GSH  A 301 ( 4.9A)
None
None
None
None
 0.41A 5d9wA-5lolA:
31.4		 5d9wA-5lolA:
68.98