SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5lon'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGX_A_SALA102_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 5lon KLLA0E01827P
(Kluyveromyces
lactis) 		4 / 7 VAL B 143
ILE B 175
TYR B 172
ILE B 171
 None
 0.96A 3hgxA-5lonB:
undetectable		 3hgxA-5lonB:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KF9_A_ACTA407_0
(GLUTATHIONE
S-TRANSFERASE
PROTEIN)		 5lon KLLA0E01827P
(Kluyveromyces
lactis) 		3 / 3 GLU B   7
ARG B  10
HIS B  31
 None
 0.85A 4kf9A-5lonB:
undetectable		 4kf9A-5lonB:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WOZ_F_MN9F401_0
(N-ACETYLNEURAMINATE
LYASE)		 5lon KLLA0E01827P
(Kluyveromyces
lactis) 		4 / 5 LEU B  29
TYR B 177
LEU B 174
THR B 184
 None
 1.26A 4wozF-5lonB:
undetectable
4wozH-5lonB:
undetectable		 4wozF-5lonB:
22.07
4wozH-5lonB:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 5lon KLLA0E01827P
(Kluyveromyces
lactis) 		4 / 4 GLY B  52
LEU B  28
PHE B  15
ILE B  18
 None
 0.71A 4xv2A-5lonB:
undetectable		 4xv2A-5lonB:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_A_STRA604_1
(CYTOCHROME P450
21-HYDROXYLASE)		 5lon KLLA0E01827P
(Kluyveromyces
lactis) 		5 / 12 VAL B 141
LEU B 178
ILE B 116
GLY B 100
LEU B  54
 None
 0.95A 4y8wA-5lonB:
undetectable		 4y8wA-5lonB:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_B_STRB603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 5lon KLLA0E01827P
(Kluyveromyces
lactis) 		5 / 12 VAL B 141
LEU B 178
ILE B 116
GLY B 100
LEU B  54
 None
 1.03A 4y8wB-5lonB:
undetectable		 4y8wB-5lonB:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_B_CELB602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5lon KLLA0E01827P
(Kluyveromyces
lactis) 		4 / 6 VAL B  17
VAL B  53
ILE B 171
PHE B  30
 None
 1.02A 5jw1B-5lonB:
undetectable		 5jw1B-5lonB:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NKN_A_LOCA201_2
(NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN)		 5lon KLLA0E01827P
(Kluyveromyces
lactis) 		3 / 3 VAL B  37
LYS B 151
MET B 139
 None
 1.01A 5nknA-5lonB:
undetectable		 5nknA-5lonB:
17.65