SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5lp7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT4_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 5lp7 ACETYL-COA
ACETYLTRANSFERASE
(Bacillus
subtilis) 		5 / 12 LEU H  38
ALA H  69
ALA H  73
VAL H  43
MET H  53
 None
 0.99A 1kt4A-5lp7H:
undetectable		 1kt4A-5lp7H:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT7_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 5lp7 ACETYL-COA
ACETYLTRANSFERASE
(Bacillus
subtilis) 		5 / 11 LEU H  38
ALA H  69
VAL H  43
MET H  75
MET H  53
 None
 1.45A 1kt7A-5lp7H:
undetectable		 1kt7A-5lp7H:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_C_SAMC303_0
(HEMK PROTEIN)		 5lp7 ACETYL-COA
ACETYLTRANSFERASE
(Bacillus
subtilis) 		5 / 12 ILE H 235
GLY H 161
ALA H 165
PRO H 248
ALA H 319
 None
 1.08A 1sg9C-5lp7H:
undetectable		 1sg9C-5lp7H:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_B_SALB503_1
(SALICYLATE
SYNTHETASE, IRP9)		 5lp7 ACETYL-COA
ACETYLTRANSFERASE
(Bacillus
subtilis) 		5 / 11 ILE H 358
GLU H 198
GLY H 342
THR H 361
GLU H 318
 None
 1.46A 2fn1B-5lp7H:
undetectable		 2fn1B-5lp7H:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_1
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 5lp7 ACETYL-COA
ACETYLTRANSFERASE
(Bacillus
subtilis) 		5 / 12 ALA H 376
ALA H 353
PHE H  14
ARG H 357
LEU H 259
 None
 1.18A 2nyrA-5lp7H:
undetectable		 2nyrA-5lp7H:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BSZ_E_RTLE177_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 5lp7 ACETYL-COA
ACETYLTRANSFERASE
(Bacillus
subtilis) 		5 / 11 LEU H  38
ALA H  73
VAL H  43
MET H  75
MET H  53
 None
 1.25A 3bszE-5lp7H:
undetectable		 3bszE-5lp7H:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKK_A_SAMA301_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 5lp7 ACETYL-COA
ACETYLTRANSFERASE
(Bacillus
subtilis) 		5 / 12 GLY H 114
GLY H 352
ALA H 256
MET H  34
LEU H  84
 None
 0.97A 3ckkA-5lp7H:
undetectable		 3ckkA-5lp7H:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKK_A_SAMA301_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 5lp7 ACETYL-COA
ACETYLTRANSFERASE
(Bacillus
subtilis) 		5 / 12 GLY H 385
GLY H 283
ALA H 387
LEU H 289
GLU H 288
 None
 1.03A 3ckkA-5lp7H:
undetectable		 3ckkA-5lp7H:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_B_REMB350_1
(RENIN)		 5lp7 ACETYL-COA
ACETYLTRANSFERASE
(Bacillus
subtilis) 		5 / 12 GLY H  31
VAL H 202
ALA H  26
SER H 117
SER H  61
 None
 1.11A 3d91B-5lp7H:
undetectable		 3d91B-5lp7H:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MB5_A_SAMA301_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5lp7 ACETYL-COA
ACETYLTRANSFERASE
(Bacillus
subtilis) 		4 / 4 GLY H  15
GLU H 218
ASP H 215
ASP H 252
 None
 1.30A 3mb5A-5lp7H:
undetectable		 3mb5A-5lp7H:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_A_SAMA300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5lp7 ACETYL-COA
ACETYLTRANSFERASE
(Bacillus
subtilis) 		5 / 12 ALA H 356
GLY H 113
GLY H 352
MET H  53
ALA H   9
 None
 1.12A 3ou6A-5lp7H:
undetectable		 3ou6A-5lp7H:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5lp7 ACETYL-COA
ACETYLTRANSFERASE
(Bacillus
subtilis) 		5 / 12 ALA H 356
GLY H 113
GLY H 352
MET H  53
ALA H   9
 None
 1.12A 3ou6B-5lp7H:
undetectable		 3ou6B-5lp7H:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5lp7 ACETYL-COA
ACETYLTRANSFERASE
(Bacillus
subtilis) 		5 / 12 ALA H 356
GLY H 113
GLY H 352
MET H  53
ALA H   9
 None
 1.13A 3ou7B-5lp7H:
undetectable		 3ou7B-5lp7H:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KR4_C_AICC401_1
(OUTER MEMBRANE
PROTEIN F)		 5lp7 ACETYL-COA
ACETYLTRANSFERASE
(Bacillus
subtilis) 		4 / 8 ARG H 369
ARG H 185
ASP H 334
ARG H 181
 None
 1.26A 4kr4C-5lp7H:
undetectable		 4kr4C-5lp7H:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDP_H_EVPH2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B)		 5lp7 ACETYL-COA
ACETYLTRANSFERASE
(Bacillus
subtilis) 		4 / 6 GLU H 192
GLY H 372
ASP H 312
GLY H 370
 None
 0.87A 5cdpA-5lp7H:
undetectable
5cdpB-5lp7H:
undetectable		 5cdpA-5lp7H:
22.22
5cdpB-5lp7H:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_1
(CYP51 VARIANT1)		 5lp7 ACETYL-COA
ACETYLTRANSFERASE
(Bacillus
subtilis) 		5 / 12 ALA H 124
TYR H 123
TYR H 236
PHE H 320
ILE H 242
 None
 1.05A 5fsaA-5lp7H:
undetectable		 5fsaA-5lp7H:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_B_CHDB401_0
(BILE SALT HYDROLASE)		 5lp7 ACETYL-COA
ACETYLTRANSFERASE
(Bacillus
subtilis) 		5 / 10 ILE H 102
LEU H 259
PHE H 257
ALA H  41
LEU H  38
 None
 1.17A 5y7pB-5lp7H:
undetectable		 5y7pB-5lp7H:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_D_CHDD401_0
(BILE SALT HYDROLASE)		 5lp7 ACETYL-COA
ACETYLTRANSFERASE
(Bacillus
subtilis) 		5 / 10 ILE H 102
LEU H 259
PHE H 257
ALA H  41
LEU H  38
 None
 1.16A 5y7pD-5lp7H:
undetectable		 5y7pD-5lp7H:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_H_CHDH401_0
(BILE SALT HYDROLASE)		 5lp7 ACETYL-COA
ACETYLTRANSFERASE
(Bacillus
subtilis) 		5 / 10 ILE H 102
LEU H 259
PHE H 257
ALA H  41
LEU H  38
 None
 1.18A 5y7pH-5lp7H:
undetectable		 5y7pH-5lp7H:
21.00