SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5lq3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPV_B_478B200_2
(HIV-1 PROTEASE)		 5lq3 CMEB
(Campylobacter
jejuni) 		5 / 9 ALA A 411
ASP A 409
VAL A 407
PRO A 375
VAL A 376
 None
 0.95A 1hpvB-5lq3A:
undetectable		 1hpvB-5lq3A:
7.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2501_0
(FERROCHELATASE)		 5lq3 CMEB
(Campylobacter
jejuni) 		5 / 12 LEU A  28
PHE A 382
LEU A 379
ILE A  33
VAL A 343
 None
 1.25A 1hrkB-5lq3A:
undetectable		 1hrkB-5lq3A:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2503_0
(FERROCHELATASE)		 5lq3 CMEB
(Campylobacter
jejuni) 		4 / 4 LEU A1019
PRO A1018
LEU A 533
ARG A 535
 None
 1.28A 1hrkB-5lq3A:
undetectable		 1hrkB-5lq3A:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_A_115A2_2
(HMG-COA REDUCTASE)		 5lq3 CMEB
(Campylobacter
jejuni) 		4 / 8 GLU A 440
ASN A 417
LEU A 965
ALA A 961
 None
 0.88A 1hwiB-5lq3A:
6.2		 1hwiB-5lq3A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_D_115D3_1
(HMG-COA REDUCTASE)		 5lq3 CMEB
(Campylobacter
jejuni) 		4 / 8 GLU A 440
ASN A 417
LEU A 965
ALA A 961
 None
 0.87A 1hwiC-5lq3A:
6.3		 1hwiC-5lq3A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J36_A_LPRA801_2
(ANGIOTENSIN
CONVERTING ENZYME)		 5lq3 CMEB
(Campylobacter
jejuni) 		4 / 4 ARG A 812
ALA A  55
SER A  83
TYR A 687
 None
 1.32A 1j36A-5lq3A:
0.0		 1j36A-5lq3A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J36_B_LPRB802_2
(ANGIOTENSIN
CONVERTING ENZYME)		 5lq3 CMEB
(Campylobacter
jejuni) 		4 / 4 ARG A 812
ALA A  55
SER A  83
TYR A 687
 None
 1.32A 1j36B-5lq3A:
0.0		 1j36B-5lq3A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KB9_A_PCFA514_0
(CYTOCHROME B
CYTOCHROME C1, HEME
PROTEIN
UBIQUINOL-CYTOCHROME
C REDUCTASE COMPLEX
CORE PROTEIN I
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 5lq3 CMEB
(Campylobacter
jejuni) 		4 / 8 SER A 670
ILE A  97
PHE A 465
VAL A 562
 None
 1.08A 1kb9A-5lq3A:
2.5
1kb9C-5lq3A:
undetectable
1kb9D-5lq3A:
undetectable
1kb9E-5lq3A:
undetectable		 1kb9A-5lq3A:
19.55
1kb9C-5lq3A:
17.55
1kb9D-5lq3A:
12.08
1kb9E-5lq3A:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_B_DMEB996_1
(ACETYLCHOLINESTERASE)		 5lq3 CMEB
(Campylobacter
jejuni) 		4 / 6 TYR A 678
ILE A  77
TYR A  94
GLY A 856
 None
 1.05A 1maaB-5lq3A:
undetectable
1maaD-5lq3A:
undetectable		 1maaB-5lq3A:
19.77
1maaD-5lq3A:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RLB_E_REAE176_1
(RETINOL BINDING
PROTEIN)		 5lq3 CMEB
(Campylobacter
jejuni) 		5 / 10 ALA A 433
ALA A 437
VAL A 445
MET A 438
LEU A 489
 None
 1.29A 1rlbE-5lq3A:
undetectable		 1rlbE-5lq3A:
9.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T85_A_CAMA422_0
(CYTOCHROME P450-CAM)		 5lq3 CMEB
(Campylobacter
jejuni) 		4 / 7 THR A 845
LEU A 846
VAL A 679
VAL A 710
 None
 1.02A 1t85A-5lq3A:
undetectable		 1t85A-5lq3A:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TDR_A_MTXA170_1
(TELLUROMETHIONYL
DIHYDROFOLATE
REDUCTASE)		 5lq3 CMEB
(Campylobacter
jejuni) 		5 / 12 ILE A 767
ALA A 769
THR A 201
ILE A 200
LEU A 253
 None
 1.11A 1tdrA-5lq3A:
undetectable		 1tdrA-5lq3A:
8.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_C_URFC999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 5lq3 CMEB
(Campylobacter
jejuni) 		4 / 5 MET A 625
ALA A 623
ILE A 574
ASP A 590
 None
 1.17A 1upfC-5lq3A:
undetectable		 1upfC-5lq3A:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)		 5lq3 CMEB
(Campylobacter
jejuni) 		5 / 10 THR A 845
THR A 712
LEU A 846
VAL A 679
VAL A 710
 None
 1.31A 2cp4A-5lq3A:
undetectable		 2cp4A-5lq3A:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC8_0
(ACTINOMYCIN D)		 5lq3 CMEB
(Campylobacter
jejuni) 		3 / 3 PRO A 719
THR A 717
PRO A 807
 None
 0.76A 2d55C-5lq3A:
undetectable		 2d55C-5lq3A:
2.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EGV_A_SAMA1300_0
(UPF0088 PROTEIN
AQ_165)		 5lq3 CMEB
(Campylobacter
jejuni) 		5 / 12 LEU A1002
GLY A1004
GLY A 906
LEU A 928
LEU A 932
 None
 0.96A 2egvA-5lq3A:
undetectable		 2egvA-5lq3A:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EGV_B_SAMB1400_0
(UPF0088 PROTEIN
AQ_165)		 5lq3 CMEB
(Campylobacter
jejuni) 		5 / 12 LEU A1002
GLY A1004
GLY A 906
LEU A 928
LEU A 932
 None
 1.00A 2egvB-5lq3A:
undetectable		 2egvB-5lq3A:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA703_0
(FERROCHELATASE)		 5lq3 CMEB
(Campylobacter
jejuni) 		4 / 4 LEU A1019
PRO A1018
LEU A 533
ARG A 535
 None
 1.39A 2hrcA-5lq3A:
undetectable		 2hrcA-5lq3A:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_B_CHDB1604_0
(FERROCHELATASE)		 5lq3 CMEB
(Campylobacter
jejuni) 		4 / 4 LEU A1019
PRO A1018
LEU A 533
ARG A 535
 None
 1.22A 2hrcB-5lq3A:
undetectable		 2hrcB-5lq3A:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_A_J01A1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 5lq3 CMEB
(Campylobacter
jejuni) 		5 / 12 LEU A 400
ILE A 483
VAL A 407
ALA A 403
LEU A 385
 None
 1.01A 2japA-5lq3A:
undetectable		 2japA-5lq3A:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_B_J01B1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 5lq3 CMEB
(Campylobacter
jejuni) 		5 / 12 LEU A 400
ILE A 483
VAL A 407
ALA A 403
LEU A 385
 None
 1.04A 2japB-5lq3A:
undetectable		 2japB-5lq3A:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_C_J01C1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 5lq3 CMEB
(Campylobacter
jejuni) 		5 / 12 LEU A 400
ILE A 483
VAL A 407
ALA A 403
LEU A 385
 None
 1.02A 2japC-5lq3A:
undetectable		 2japC-5lq3A:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_D_J01D1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 5lq3 CMEB
(Campylobacter
jejuni) 		5 / 12 LEU A 400
ILE A 483
VAL A 407
ALA A 403
LEU A 385
 None
 1.01A 2japD-5lq3A:
undetectable		 2japD-5lq3A:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A130_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 5lq3 CMEB
(Campylobacter
jejuni) 		5 / 12 LEU A 361
ILE A 369
THR A 492
ILE A 404
LEU A 350
 None
 1.03A 2jn3A-5lq3A:
undetectable		 2jn3A-5lq3A:
8.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5lq3 CMEB
(Campylobacter
jejuni) 		4 / 4 LEU A1019
PRO A1018
LEU A 533
ARG A 535
 None
 1.32A 2pnjB-5lq3A:
undetectable		 2pnjB-5lq3A:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA508_0
(CHORISMATE SYNTHASE)		 5lq3 CMEB
(Campylobacter
jejuni) 		4 / 5 LEU A 489
ASP A 410
ALA A 488
ILE A 446
 None
 1.07A 2qhfA-5lq3A:
undetectable		 2qhfA-5lq3A:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7B_B_BEZB1529_0
(BENZOATE-COENZYME A
LIGASE)		 5lq3 CMEB
(Campylobacter
jejuni) 		5 / 9 TYR A  50
ALA A  53
GLY A  52
GLY A  87
ILE A  58
 None
 1.10A 2v7bB-5lq3A:
3.5		 2v7bB-5lq3A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 5lq3 CMEB
(Campylobacter
jejuni) 		5 / 12 VAL A 209
PHE A 756
ASN A 766
SER A 185
PHE A 248
 None
 1.41A 2vdyB-5lq3A:
undetectable		 2vdyB-5lq3A:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1374_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 5lq3 CMEB
(Campylobacter
jejuni) 		4 / 5 TYR A 144
PRO A 328
ASN A 284
LEU A 597
 None
 1.45A 2wekA-5lq3A:
undetectable		 2wekA-5lq3A:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZSE_A_PAUA600_0
(PANTOTHENATE KINASE)		 5lq3 CMEB
(Campylobacter
jejuni) 		4 / 7 PHE A 967
PHE A 518
ILE A1014
ASN A 936
 None
 0.92A 2zseA-5lq3A:
undetectable		 2zseA-5lq3A:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_Q_TRPQ1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5lq3 CMEB
(Campylobacter
jejuni) 		4 / 8 GLN A 103
ILE A  70
VAL A  93
VAL A  44
 None
 0.78A 3fi0Q-5lq3A:
undetectable		 3fi0Q-5lq3A:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_A_ADNA438_1
(ADENOSYLHOMOCYSTEINA
SE)		 5lq3 CMEB
(Campylobacter
jejuni) 		5 / 12 LEU A 400
THR A 476
LEU A  31
LEU A 385
GLY A 384
 None
 1.38A 3g1uA-5lq3A:
undetectable		 3g1uA-5lq3A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCS_A_BAXA401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 5lq3 CMEB
(Campylobacter
jejuni) 		4 / 6 MET A 371
VAL A 374
LEU A  22
ILE A 354
 None
 0.95A 3gcsA-5lq3A:
undetectable		 3gcsA-5lq3A:
16.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HZN_D_ACTD229_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5lq3 CMEB
(Campylobacter
jejuni) 		4 / 4 ASP A 612
GLY A 610
LYS A 619
GLU A 620
 None
 1.36A 3hznD-5lq3A:
2.5		 3hznD-5lq3A:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_A_AICA375_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 5lq3 CMEB
(Campylobacter
jejuni) 		5 / 11 GLY A1005
LEU A 932
ASN A 936
SER A1010
LEU A 928
 None
 1.22A 3ndvA-5lq3A:
undetectable
3ndvB-5lq3A:
undetectable		 3ndvA-5lq3A:
17.53
3ndvB-5lq3A:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_B_AICB376_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 5lq3 CMEB
(Campylobacter
jejuni) 		5 / 11 LEU A 928
GLY A1005
LEU A 932
ASN A 936
SER A1010
 None
 1.23A 3ndvA-5lq3A:
undetectable
3ndvB-5lq3A:
undetectable		 3ndvA-5lq3A:
17.53
3ndvB-5lq3A:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_C_AICC375_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 5lq3 CMEB
(Campylobacter
jejuni) 		5 / 11 GLY A1005
LEU A 932
ASN A 936
SER A1010
LEU A 928
 None
 1.24A 3ndvC-5lq3A:
undetectable
3ndvD-5lq3A:
undetectable		 3ndvC-5lq3A:
17.53
3ndvD-5lq3A:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_D_AICD374_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 5lq3 CMEB
(Campylobacter
jejuni) 		5 / 11 LEU A 928
GLY A1005
LEU A 932
ASN A 936
SER A1010
 None
 1.23A 3ndvC-5lq3A:
undetectable
3ndvD-5lq3A:
undetectable		 3ndvC-5lq3A:
17.53
3ndvD-5lq3A:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWW_A_ROCA1001_1
(ENDOTHIAPEPSIN)		 5lq3 CMEB
(Campylobacter
jejuni) 		5 / 12 ILE A 412
PHE A 986
ILE A 985
THR A 978
ILE A1003
 None
 0.90A 3pwwA-5lq3A:
undetectable		 3pwwA-5lq3A:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QG2_B_CP6B709_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5lq3 CMEB
(Campylobacter
jejuni) 		5 / 11 ILE A 571
MET A 606
PHE A 626
ILE A 179
LEU A 613
 None
 1.16A 3qg2B-5lq3A:
undetectable		 3qg2B-5lq3A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3C_A_017A201_2
(HIV-1 PROTEASE)		 5lq3 CMEB
(Campylobacter
jejuni) 		5 / 10 ALA A 474
VAL A 455
GLY A 925
ALA A 871
VAL A 459
 None
 0.78A 3t3cB-5lq3A:
undetectable		 3t3cB-5lq3A:
6.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3C_A_017A201_2
(HIV-1 PROTEASE)		 5lq3 CMEB
(Campylobacter
jejuni) 		5 / 10 ALA A 474
VAL A 455
ILE A 920
ALA A 871
VAL A 459
 None
 1.05A 3t3cB-5lq3A:
undetectable		 3t3cB-5lq3A:
6.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQF_B_QPSB951_1
(ALPHA-GLUCAN
PHOSPHORYLASE 2,
CYTOSOLIC)		 5lq3 CMEB
(Campylobacter
jejuni) 		4 / 8 ARG A 966
GLU A 942
GLU A 947
LYS A 951
 None
 0.90A 4bqfB-5lq3A:
undetectable		 4bqfB-5lq3A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9L_A_CAMA1419_0
(CYTOCHROME P450)		 5lq3 CMEB
(Campylobacter
jejuni) 		6 / 12 ILE A 413
LEU A 932
GLY A 931
VAL A 449
ASP A 410
VAL A 481
 None
 1.31A 4c9lA-5lq3A:
undetectable		 4c9lA-5lq3A:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9L_B_CAMB1419_0
(CYTOCHROME P450)		 5lq3 CMEB
(Campylobacter
jejuni) 		5 / 12 ILE A 413
LEU A 932
GLY A 931
ASP A 410
VAL A 481
 None
 0.82A 4c9lB-5lq3A:
undetectable		 4c9lB-5lq3A:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_B_CAMB1420_0
(CYTOCHROME P450)		 5lq3 CMEB
(Campylobacter
jejuni) 		5 / 10 LEU A 932
GLY A 931
VAL A 449
ASP A 410
VAL A 481
 None
 1.35A 4c9nB-5lq3A:
undetectable		 4c9nB-5lq3A:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9O_A_CAMA423_0
(CYTOCHROME P450)		 5lq3 CMEB
(Campylobacter
jejuni) 		6 / 12 ILE A 413
LEU A 932
GLY A 931
VAL A 449
ASP A 410
VAL A 481
 None
 1.30A 4c9oA-5lq3A:
1.5		 4c9oA-5lq3A:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9O_B_CAMB423_0
(CYTOCHROME P450)		 5lq3 CMEB
(Campylobacter
jejuni) 		6 / 12 ILE A 413
LEU A 932
GLY A 931
VAL A 449
ASP A 410
VAL A 481
 None
 1.29A 4c9oB-5lq3A:
undetectable		 4c9oB-5lq3A:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB6_C_VLBC503_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		 5lq3 CMEB
(Campylobacter
jejuni) 		5 / 12 VAL A 481
PRO A 375
ILE A  20
VAL A 487
ILE A 372
 None
 1.32A 4eb6B-5lq3A:
undetectable
4eb6C-5lq3A:
undetectable		 4eb6B-5lq3A:
19.55
4eb6C-5lq3A:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJW_A_SRYA2001_2
(TRANSCRIPTIONAL
REGULATOR TCAR)		 5lq3 CMEB
(Campylobacter
jejuni) 		4 / 6 ILE A 428
ASN A 425
GLU A 416
VAL A 441
 None
 0.83A 4ejwB-5lq3A:
0.7		 4ejwB-5lq3A:
8.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_A_MIXA1301_1
(DNA TOPOISOMERASE
2-BETA)		 5lq3 CMEB
(Campylobacter
jejuni) 		4 / 7 GLY A 662
ILE A 643
ASN A 647
MET A 292
 None
 0.85A 4g0vA-5lq3A:
undetectable		 4g0vA-5lq3A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUK_A_RBFA201_2
(BLUE-LIGHT
PHOTORECEPTOR)		 5lq3 CMEB
(Campylobacter
jejuni) 		5 / 9 VAL A 445
ILE A 448
LEU A 452
ILE A 413
GLY A 405
 None
 1.07A 4kukA-5lq3A:
undetectable		 4kukA-5lq3A:
8.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5lq3 CMEB
(Campylobacter
jejuni) 		4 / 7 THR A 845
LEU A 846
VAL A 679
VAL A 710
 None
 0.98A 4l4gA-5lq3A:
undetectable		 4l4gA-5lq3A:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_C_SAMC301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 5lq3 CMEB
(Campylobacter
jejuni) 		5 / 12 GLY A 906
GLY A1004
LEU A 913
LEU A 910
ALA A1009
 None
 1.13A 4lg1C-5lq3A:
undetectable		 4lg1C-5lq3A:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A202_2
(PROTEASE)		 5lq3 CMEB
(Campylobacter
jejuni) 		5 / 9 ALA A 411
ASP A 409
VAL A 407
PRO A 375
VAL A 376
 None
 1.12A 4ll3B-5lq3A:
undetectable		 4ll3B-5lq3A:
7.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAE_A_NIZA804_1
(CATALASE-PEROXIDASE)		 5lq3 CMEB
(Campylobacter
jejuni) 		4 / 6 PHE A 798
TYR A 733
LEU A 735
THR A 743
 None
 1.34A 4paeA-5lq3A:
undetectable		 4paeA-5lq3A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RFQ_A_SAMA401_1
(HISTIDINE PROTEIN
METHYLTRANSFERASE 1
HOMOLOG)		 5lq3 CMEB
(Campylobacter
jejuni) 		4 / 4 THR A  43
GLY A 174
ASP A 175
SER A 297
 None
 1.18A 4rfqA-5lq3A:
undetectable		 4rfqA-5lq3A:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4S0V_A_SUVA2001_2
(HUMAN OREXIN
RECEPTOR TYPE 2
FUSION PROTEIN TO P.
ABYSII GLYCOGEN
SYNTHASE)		 5lq3 CMEB
(Campylobacter
jejuni) 		4 / 5 ILE A  66
PRO A  65
TYR A 687
VAL A 810
 None
 0.67A 4s0vA-5lq3A:
undetectable		 4s0vA-5lq3A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X61_A_SAMA701_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 5lq3 CMEB
(Campylobacter
jejuni) 		5 / 12 LEU A 646
PRO A 577
LEU A 576
MET A 625
GLU A 588
 None
 1.29A 4x61A-5lq3A:
undetectable		 4x61A-5lq3A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE1_A_X2NA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5lq3 CMEB
(Campylobacter
jejuni) 		4 / 5 VAL A 841
TYR A 859
ILE A  97
THR A 867
 None
 1.32A 4ze1A-5lq3A:
undetectable		 4ze1A-5lq3A:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E8Q_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 5lq3 CMEB
(Campylobacter
jejuni) 		5 / 12 ILE A 767
ALA A 769
THR A 201
ILE A 200
LEU A 253
 None
 1.08A 5e8qB-5lq3A:
undetectable		 5e8qB-5lq3A:
8.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EAJ_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 5lq3 CMEB
(Campylobacter
jejuni) 		5 / 12 ILE A 767
ALA A 769
THR A 201
ILE A 200
LEU A 253
 None
 1.11A 5eajB-5lq3A:
undetectable		 5eajB-5lq3A:
8.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EML_A_SAMA701_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 5lq3 CMEB
(Campylobacter
jejuni) 		5 / 12 LEU A 646
PRO A 577
LEU A 576
MET A 625
GLU A 588
 None
 1.32A 5emlA-5lq3A:
undetectable		 5emlA-5lq3A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_A_ACTA1231_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT
PUTATIVE XANTHINE
DEHYDROGENASE YAGT
IRON-SULFUR-BINDING
SUBUNIT)		 5lq3 CMEB
(Campylobacter
jejuni) 		3 / 3 ARG A 786
THR A 201
ASP A 204
 None
 0.96A 5g5gA-5lq3A:
0.9
5g5gB-5lq3A:
undetectable		 5g5gA-5lq3A:
12.69
5g5gB-5lq3A:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HS6_A_J3ZA302_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE 14)		 5lq3 CMEB
(Campylobacter
jejuni) 		4 / 8 LEU A 998
LEU A1002
MET A1006
THR A 978
 None
 1.15A 5hs6A-5lq3A:
undetectable		 5hs6A-5lq3A:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_CE9A402_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)		 5lq3 CMEB
(Campylobacter
jejuni) 		5 / 12 ALA A 403
LEU A 402
ALA A 399
LEU A 385
THR A 381
 None
 1.17A 5k9dA-5lq3A:
undetectable		 5k9dA-5lq3A:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_A_SAMA304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 5lq3 CMEB
(Campylobacter
jejuni) 		5 / 12 GLY A 931
ILE A 882
GLN A 886
LEU A 450
LEU A 452
 None
 0.99A 5l0zA-5lq3A:
undetectable		 5l0zA-5lq3A:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 5lq3 CMEB
(Campylobacter
jejuni) 		5 / 12 ILE A 469
LEU A 561
PHE A 465
GLY A 464
GLY A 467
 None
 1.02A 5l6eA-5lq3A:
undetectable		 5l6eA-5lq3A:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L7I_B_VISB1202_1
(SMOOTHENED
HOMOLOG,SOLUBLE
CYTOCHROME
B562,SMOOTHENED
HOMOLOG)		 5lq3 CMEB
(Campylobacter
jejuni) 		5 / 12 ASP A 410
PRO A 444
ASN A 936
LEU A 932
MET A1006
 None
 1.21A 5l7iB-5lq3A:
0.2		 5l7iB-5lq3A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND2_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 5lq3 CMEB
(Campylobacter
jejuni) 		5 / 12 VAL A 407
ASP A 409
ALA A 403
SER A 480
LEU A 928
 None
 1.40A 5nd2B-5lq3A:
undetectable		 5nd2B-5lq3A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UJX_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 5lq3 CMEB
(Campylobacter
jejuni) 		5 / 12 ILE A 767
ALA A 769
THR A 201
ILE A 200
LEU A 253
 None
 1.10A 5ujxB-5lq3A:
undetectable		 5ujxB-5lq3A:
8.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YK2_A_ERYA501_0
(PROBABLE CONSERVED
ATP-BINDING PROTEIN
ABC TRANSPORTER)		 5lq3 CMEB
(Campylobacter
jejuni) 		5 / 11 GLY A 485
ASP A 410
ALA A 488
ILE A 446
VAL A 449
 None
 0.98A 5yk2A-5lq3A:
undetectable		 5yk2A-5lq3A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BZO_C_FI8C1201_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 5lq3 CMEB
(Campylobacter
jejuni) 		5 / 12 THR A 924
GLN A 923
VAL A 557
SER A 907
VAL A 904
 None
 1.22A 6bzoC-5lq3A:
undetectable		 6bzoC-5lq3A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CM4_A_8NUA2001_1
(D(2) DOPAMINE
RECEPTOR, ENDOLYSIN
CHIMERA)		 5lq3 CMEB
(Campylobacter
jejuni) 		4 / 4 ASP A  68
ALA A  59
SER A  81
PHE A 816
 None
 1.48A 6cm4A-5lq3A:
undetectable		 6cm4A-5lq3A:
18.66