SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5lq6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_A_9CRA502_1
(CYTOCHROME P450 2C8)		 5lq6 VIRULENCE PROTEIN
VSDE
(Salmonella
enterica) 		5 / 12 ILE A 189
SER A 183
LEU A 190
VAL A 167
ILE A 196
 None
 1.04A 2nnhA-5lq6A:
undetectable		 2nnhA-5lq6A:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 5lq6 VIRULENCE PROTEIN
VSDE
(Salmonella
enterica) 		5 / 12 ILE A 146
ASN A 165
SER A 144
PHE A 113
HIS A  85
 None
 1.33A 2vdyA-5lq6A:
undetectable		 2vdyA-5lq6A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID802_0
(GLUTAMATE RECEPTOR 2)		 5lq6 VIRULENCE PROTEIN
VSDE
(Salmonella
enterica) 		3 / 3 SER A 105
ASP A 163
ASN A 165
 None
 0.97A 3lslA-5lq6A:
undetectable
3lslD-5lq6A:
undetectable		 3lslA-5lq6A:
19.64
3lslD-5lq6A:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA605_1
(CHITINASE)		 5lq6 VIRULENCE PROTEIN
VSDE
(Salmonella
enterica) 		3 / 3 TRP A 184
ILE A 157
SER A 160
 None
 0.92A 5gqbA-5lq6A:
undetectable		 5gqbA-5lq6A:
17.67