SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ls2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_B_FFOB505_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5ls2 LYSM TYPE RECEPTOR
KINASE
(Lotus
japonicus) 		5 / 12 LEU A 165
LEU A  34
ASN A  69
SER A 217
GLY A 216
 None
 1.00A 2vmyA-5ls2A:
undetectable		 2vmyA-5ls2A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1004_1
(HEMOLYTIC LECTIN
CEL-III)		 5ls2 LYSM TYPE RECEPTOR
KINASE
(Lotus
japonicus) 		4 / 4 ASP A 106
GLY A 145
TYR A 105
GLN A 108
 None
 1.49A 3w9tC-5ls2A:
0.0		 3w9tC-5ls2A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE505_1
(HEMOLYTIC LECTIN
CEL-III)		 5ls2 LYSM TYPE RECEPTOR
KINASE
(Lotus
japonicus) 		4 / 5 ASP A 106
GLY A 145
TYR A 105
GLN A 108
 None
 1.48A 3w9tE-5ls2A:
undetectable		 3w9tE-5ls2A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_A_RKEA401_1
(PROTON-GATED ION
CHANNEL)		 5ls2 LYSM TYPE RECEPTOR
KINASE
(Lotus
japonicus) 		4 / 8 TYR A 218
ASP A  71
VAL A 167
LEU A 186
 None
 1.09A 4f8hA-5ls2A:
undetectable
4f8hB-5ls2A:
undetectable		 4f8hA-5ls2A:
20.32
4f8hB-5ls2A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_B_CVIB602_0
(ACETYLCHOLINESTERASE)		 5ls2 LYSM TYPE RECEPTOR
KINASE
(Lotus
japonicus) 		4 / 8 THR A 126
LEU A 130
TYR A 113
VAL A 107
 None
 1.25A 5ov9B-5ls2A:
undetectable		 5ov9B-5ls2A:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5ls2 LYSM TYPE RECEPTOR
KINASE
(Lotus
japonicus) 		3 / 3 LEU A 124
ASN A  69
LEU A  41
 None
 0.66A 6exiD-5ls2A:
undetectable		 6exiD-5ls2A:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MDQ_A_TESA604_0
(SERUM ALBUMIN)		 5ls2 LYSM TYPE RECEPTOR
KINASE
(Lotus
japonicus) 		4 / 8 ALA A  35
GLY A 164
LEU A 165
ALA A 211
 None
 0.76A 6mdqA-5ls2A:
undetectable		 6mdqA-5ls2A:
13.57