SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5lsj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_2_BEZ2801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 5lsj KINETOCHORE-ASSOCIAT
ED PROTEIN DSN1
HOMOLOG
KINETOCHORE-ASSOCIAT
ED PROTEIN NSL1
HOMOLOG
(Homo
sapiens;
Homo
sapiens) 		4 / 4 LEU N 148
ARG D 242
ILE N 147
ILE D 239
 None
 0.94A 5dzk2-5lsjN:
undetectable
5dzkM-5lsjN:
undetectable
5dzkN-5lsjN:
undetectable		 5dzk2-5lsjN:
0.86
5dzkM-5lsjN:
20.11
5dzkN-5lsjN:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_4_BEZ4801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5lsj KINETOCHORE-ASSOCIAT
ED PROTEIN DSN1
HOMOLOG
KINETOCHORE-ASSOCIAT
ED PROTEIN NSL1
HOMOLOG
(Homo
sapiens;
Homo
sapiens) 		4 / 5 LEU N 148
ARG D 242
ILE N 147
ILE D 239
 None
 1.06A 5dzk4-5lsjN:
undetectable
5dzkg-5lsjN:
undetectable
5dzkm-5lsjN:
undetectable
5dzkn-5lsjN:
undetectable		 5dzk4-5lsjN:
0.86
5dzkg-5lsjN:
18.36
5dzkm-5lsjN:
20.11
5dzkn-5lsjN:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_V_BEZV801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 5lsj KINETOCHORE-ASSOCIAT
ED PROTEIN DSN1
HOMOLOG
KINETOCHORE-ASSOCIAT
ED PROTEIN NSL1
HOMOLOG
(Homo
sapiens;
Homo
sapiens) 		4 / 4 ILE N 147
ILE D 239
ARG D 242
LEU N 148
 None
 1.08A 5dzkh-5lsjN:
undetectable
5dzkn-5lsjN:
undetectable
5dzkv-5lsjN:
undetectable		 5dzkh-5lsjN:
20.11
5dzkn-5lsjN:
20.11
5dzkv-5lsjN:
0.86