SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5lsr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D8C_A_SORA4000_0
(MALATE SYNTHASE G)		 5lsr CCMP
(Synechococcus
elongatus) 		3 / 3 GLN A 146
HIS A 206
PRO A 106
 None
 0.70A 1d8cA-5lsrA:
undetectable		 1d8cA-5lsrA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		 5lsr CCMP
(Synechococcus
elongatus) 		5 / 11 ALA A 194
VAL A 169
ALA A 171
ALA A 149
LEU A 198
 None
 1.06A 1jinA-5lsrA:
undetectable		 1jinA-5lsrA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O02_B_JN3B1_1
(CELL INVASION
PROTEIN SIPD)		 5lsr CCMP
(Synechococcus
elongatus) 		5 / 10 ILE A  22
ALA A 152
LEU A  14
LEU A  11
VAL A   9
 None
 1.09A 3o02A-5lsrA:
undetectable
3o02B-5lsrA:
undetectable		 3o02A-5lsrA:
19.94
3o02B-5lsrA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_C_BEZC264_0
(CARNITINYL-COA
DEHYDRATASE)		 5lsr CCMP
(Synechococcus
elongatus) 		4 / 6 ALA A 155
ILE A 166
LEU A 178
ALA A 171
 None
 0.90A 3r9sC-5lsrA:
undetectable		 3r9sC-5lsrA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_B_ACTB701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)		 5lsr CCMP
(Synechococcus
elongatus) 		3 / 3 HIS A  78
GLY A  23
ILE A  22
 None
 0.64A 4k50A-5lsrA:
undetectable		 4k50A-5lsrA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5lsr CCMP
(Synechococcus
elongatus) 		5 / 12 ILE A 164
GLY A 181
PHE A 179
GLN A 168
ALA A 158
 None
 1.15A 5n0xB-5lsrA:
undetectable		 5n0xB-5lsrA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLO_A_GBQA1501_1
(SUBSTANCE-P
RECEPTOR,GLGA
GLYCOGEN
SYNTHASE,SUBSTANCE-P
RECEPTOR)		 5lsr CCMP
(Synechococcus
elongatus) 		5 / 9 ILE A  48
ILE A  46
TRP A  39
GLU A  76
ILE A  68
 None
 1.49A 6hloA-5lsrA:
undetectable		 6hloA-5lsrA:
19.27