SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5lt9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5lt9 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
PCTB
(Pseudomonas
aeruginosa) 		4 / 7 GLY A 171
ALA A 132
THR A 141
THR A 155
 None
 0.92A 1c9sT-5lt9A:
undetectable
1c9sU-5lt9A:
undetectable		 1c9sT-5lt9A:
12.90
1c9sU-5lt9A:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ6_A_CAMA502_0
(CYTOCHROME P450-CAM)		 5lt9 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
PCTB
(Pseudomonas
aeruginosa) 		4 / 5 PHE A  99
LEU A 117
VAL A 153
ASP A 173
 ARG  A 301 (-3.6A)
ARG  A 301 (-4.7A)
None
ARG  A 301 (-3.1A)
 1.21A 1dz6A-5lt9A:
undetectable		 1dz6A-5lt9A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETB_2_T442129_1
(TRANSTHYRETIN)		 5lt9 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
PCTB
(Pseudomonas
aeruginosa) 		4 / 6 GLU A  89
THR A 114
ALA A 111
LEU A 102
 None
None
ARG  A 301 (-3.3A)
None
 1.02A 1etb2-5lt9A:
undetectable		 1etb2-5lt9A:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5lt9 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
PCTB
(Pseudomonas
aeruginosa) 		4 / 7 GLY A 171
ALA A 132
THR A 141
THR A 155
 None
 0.88A 1gtfL-5lt9A:
undetectable
1gtfM-5lt9A:
undetectable		 1gtfL-5lt9A:
12.90
1gtfM-5lt9A:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M9J_A_CLWA906_1
(ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE)		 5lt9 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
PCTB
(Pseudomonas
aeruginosa) 		4 / 5 PRO A 127
TYR A 144
MET A 145
GLU A 146
 None
ARG  A 301 (-4.6A)
None
ARG  A 301 (-4.0A)
 1.12A 1m9jA-5lt9A:
undetectable		 1m9jA-5lt9A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M9J_B_CLWB907_1
(ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE)		 5lt9 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
PCTB
(Pseudomonas
aeruginosa) 		4 / 5 PRO A 127
TYR A 144
MET A 145
GLU A 146
 None
ARG  A 301 (-4.6A)
None
ARG  A 301 (-4.0A)
 1.15A 1m9jB-5lt9A:
undetectable		 1m9jB-5lt9A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA2_B_SCKB951_1
(ACETYLCHOLINESTERASE)		 5lt9 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
PCTB
(Pseudomonas
aeruginosa) 		4 / 8 TYR A 101
ASP A 173
TYR A 144
HIS A 150
 ARG  A 301 (-4.2A)
ARG  A 301 (-3.1A)
ARG  A 301 (-4.6A)
None
 1.29A 2ha2B-5lt9A:
undetectable		 2ha2B-5lt9A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_A_ACTA1397_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 5lt9 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
PCTB
(Pseudomonas
aeruginosa) 		3 / 3 PRO A 123
GLY A 103
TYR A 129
 None
 0.63A 2vouA-5lt9A:
undetectable		 2vouA-5lt9A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_B_ACTB1391_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 5lt9 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
PCTB
(Pseudomonas
aeruginosa) 		3 / 3 PRO A 123
GLY A 103
TYR A 129
 None
 0.72A 2vouB-5lt9A:
undetectable		 2vouB-5lt9A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_C_ACTC1391_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 5lt9 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
PCTB
(Pseudomonas
aeruginosa) 		3 / 3 PRO A 123
GLY A 103
TYR A 129
 None
 0.71A 2vouC-5lt9A:
undetectable		 2vouC-5lt9A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_D_VIBD223_1
(THIAMINE
PYROPHOSPHOKINASE)		 5lt9 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
PCTB
(Pseudomonas
aeruginosa) 		4 / 8 HIS A  47
LEU A 216
LEU A 243
SER A 246
 None
 1.04A 3lm8B-5lt9A:
undetectable
3lm8D-5lt9A:
undetectable		 3lm8B-5lt9A:
22.77
3lm8D-5lt9A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KKY_X_CAMX503_0
(CAMPHOR
5-MONOOXYGENASE)		 5lt9 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
PCTB
(Pseudomonas
aeruginosa) 		4 / 6 PHE A  99
LEU A 117
VAL A 153
ASP A 173
 ARG  A 301 (-3.6A)
ARG  A 301 (-4.7A)
None
ARG  A 301 (-3.1A)
 1.17A 4kkyX-5lt9A:
undetectable		 4kkyX-5lt9A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_2
(ADENOSINE KINASE)		 5lt9 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
PCTB
(Pseudomonas
aeruginosa) 		4 / 5 LEU A  46
SER A 261
LEU A  42
ASN A 184
 None
 0.98A 4n09B-5lt9A:
undetectable		 4n09B-5lt9A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_E_SORE1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5lt9 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
PCTB
(Pseudomonas
aeruginosa) 		4 / 7 ARG A 126
ASP A 173
TYR A 144
TYR A 121
 ARG  A 301 (-3.8A)
ARG  A 301 (-3.1A)
ARG  A 301 (-4.6A)
ARG  A 301 (-4.4A)
 1.40A 5a06E-5lt9A:
undetectable		 5a06E-5lt9A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_B_SAMB301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 5lt9 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
PCTB
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 253
ALA A 135
ALA A 157
ILE A 156
LEU A 140
 None
 0.91A 5bw4B-5lt9A:
undetectable		 5bw4B-5lt9A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lt9 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
PCTB
(Pseudomonas
aeruginosa) 		4 / 8 GLY A 171
ALA A 132
THR A 141
THR A 155
 None
 0.89A 5eevL-5lt9A:
undetectable
5eevV-5lt9A:
undetectable		 5eevL-5lt9A:
12.90
5eevV-5lt9A:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lt9 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
PCTB
(Pseudomonas
aeruginosa) 		4 / 8 GLY A 171
ALA A 132
THR A 141
THR A 155
 None
 0.89A 5eewL-5lt9A:
undetectable
5eewV-5lt9A:
undetectable		 5eewL-5lt9A:
12.90
5eewV-5lt9A:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lt9 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
PCTB
(Pseudomonas
aeruginosa) 		4 / 8 GLY A 171
ALA A 132
THR A 141
THR A 155
 None
 0.89A 5ef1L-5lt9A:
undetectable
5ef1V-5lt9A:
undetectable		 5ef1L-5lt9A:
12.90
5ef1V-5lt9A:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lt9 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
PCTB
(Pseudomonas
aeruginosa) 		4 / 8 GLY A 171
ALA A 132
THR A 141
THR A 155
 None
 0.89A 5ef2L-5lt9A:
undetectable
5ef2V-5lt9A:
undetectable		 5ef2L-5lt9A:
12.90
5ef2V-5lt9A:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5lt9 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
PCTB
(Pseudomonas
aeruginosa) 		4 / 8 GLY A 171
ALA A 132
THR A 141
THR A 155
 None
 0.89A 5ef3L-5lt9A:
undetectable
5ef3V-5lt9A:
undetectable		 5ef3L-5lt9A:
12.90
5ef3V-5lt9A:
12.90