SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ltm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_B_TESB904_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		4 / 7 VAL B 559
ILE B 562
HIS B 385
LEU B 319
 None
 1.03A 1j96B-5ltmB:
undetectable		 1j96B-5ltmB:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q13_A_TESA501_1
(PROSTAGLANDIN-E2
9-REDUCTASE)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		4 / 6 TYR B  66
GLU B  75
PRO B  76
VAL B  80
 None
 0.96A 1q13A-5ltmB:
undetectable		 1q13A-5ltmB:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKN_A_RALA600_1
(ESTROGEN RECEPTOR
BETA)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		5 / 12 LEU B 242
THR B 243
ALA B 246
LEU B 386
ILE B 471
 None
 0.97A 1qknA-5ltmB:
undetectable		 1qknA-5ltmB:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XL6_B_SPMB3001_1
(INWARD RECTIFIER
POTASSIUM CHANNEL)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		4 / 5 ALA B 233
TYR B 237
ALA B 123
GLN B 473
 None
 0.93A 1xl6A-5ltmB:
0.9
1xl6B-5ltmB:
1.4		 1xl6A-5ltmB:
20.44
1xl6B-5ltmB:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_A_ROFA502_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		3 / 3 ASN B 532
TRP B 531
GLN B 536
 None
 1.14A 1xoqA-5ltmB:
undetectable		 1xoqA-5ltmB:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		4 / 6 LEU B 432
LEU B 431
ILE B 379
ARG B 376
 None
 1.04A 2rlfA-5ltmB:
undetectable
2rlfB-5ltmB:
undetectable		 2rlfA-5ltmB:
6.21
2rlfB-5ltmB:
6.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_B_KLNB1498_1
(CYTOCHROME P450 3A4)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		5 / 9 PHE B 188
SER B 226
ALA B 129
GLY B 179
LEU B 181
 None
 1.05A 2v0mB-5ltmB:
undetectable		 2v0mB-5ltmB:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VJ1_A_BEZA1303_0
(SARS CORONAVIRUS
MAIN PROTEINASE)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		3 / 3 HIS B 132
MET B 147
MET B 221
 None
 1.12A 2vj1A-5ltmB:
undetectable		 2vj1A-5ltmB:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_G_RBFG200_1
(DODECIN)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		4 / 8 ARG B 140
HIS B 132
THR B 102
GLN B 101
 None
 1.30A 2vxaF-5ltmB:
undetectable
2vxaG-5ltmB:
undetectable
2vxaI-5ltmB:
undetectable		 2vxaF-5ltmB:
8.72
2vxaG-5ltmB:
8.72
2vxaI-5ltmB:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_B_SALB1305_1
(LYSR-TYPE REGULATORY
PROTEIN)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		4 / 5 SER B 331
PRO B 275
GLY B 276
TRP B 279
 None
 1.28A 2y7kB-5ltmB:
undetectable		 2y7kB-5ltmB:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7P_A_SALA1000_1
(LYSR-TYPE REGULATORY
PROTEIN)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		5 / 10 THR B  81
ILE B  77
GLY B  83
HIS B 359
PRO B 348
 None
 1.45A 2y7pA-5ltmB:
undetectable		 2y7pA-5ltmB:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7P_A_SALA1001_1
(LYSR-TYPE REGULATORY
PROTEIN)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		4 / 6 SER B 331
PRO B 275
GLY B 276
TRP B 279
 None
 1.32A 2y7pA-5ltmB:
undetectable		 2y7pA-5ltmB:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_C_SALC1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		4 / 7 THR B 178
ILE B 182
GLY B 179
PHE B 188
 None
 0.86A 2y7wC-5ltmB:
undetectable		 2y7wC-5ltmB:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		4 / 4 ARG B 490
GLN B 485
PHE B 482
LEU B 257
 None
 1.00A 3abkC-5ltmB:
0.0		 3abkC-5ltmB:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		4 / 6 ARG B 490
GLN B 485
PHE B 482
LEU B 257
 None
 1.15A 3ablP-5ltmB:
3.7
3ablW-5ltmB:
undetectable		 3ablP-5ltmB:
18.82
3ablW-5ltmB:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFL_A_5CHA693_1
(LACTOTRANSFERRIN)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		4 / 4 THR B 156
VAL B  41
GLY B 230
THR B 229
 None
 0.91A 3cflA-5ltmB:
undetectable		 3cflA-5ltmB:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_A_SAMA301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		3 / 3 SER B 286
ASP B 282
ASP B 561
 None
 0.82A 3iv6A-5ltmB:
undetectable		 3iv6A-5ltmB:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KM6_A_EAAA222_1
(GLUTATHIONE
S-TRANSFERASE P)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		5 / 10 VAL B 368
GLY B 458
VAL B 236
ILE B 439
GLY B 371
 None
 1.26A 3km6A-5ltmB:
undetectable		 3km6A-5ltmB:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPC_A_SAMA1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		5 / 11 ILE B  77
THR B  81
ILE B 350
ILE B  67
PRO B 348
 None
 1.27A 3kpcA-5ltmB:
undetectable		 3kpcA-5ltmB:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		5 / 12 ILE B  77
THR B  81
ILE B 350
ILE B  67
PRO B 348
 None
 1.13A 3kpdB-5ltmB:
undetectable		 3kpdB-5ltmB:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		5 / 12 THR B  81
ILE B 350
ASN B  68
ILE B  67
PRO B 348
 None
 1.05A 3kpdB-5ltmB:
undetectable		 3kpdB-5ltmB:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PEO_F_CU9F301_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		4 / 6 THR B 102
GLN B 101
ILE B 182
SER B  98
 None
 1.25A 3peoG-5ltmB:
undetectable		 3peoG-5ltmB:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PS9_A_SAMA670_1
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		4 / 6 GLY B 458
THR B 460
LEU B 464
ASP B 373
 None
 1.01A 3ps9A-5ltmB:
undetectable		 3ps9A-5ltmB:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_B_SAMB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		5 / 12 LEU B 181
ILE B 139
ILE B 177
ALA B 129
LEU B 151
 None
 1.17A 3uj7B-5ltmB:
undetectable		 3uj7B-5ltmB:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_1
(METHYLTRANSFERASE
NSUN4)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		3 / 3 ASP B 120
ARG B 466
ASP B 170
 None
None
MDO  B 168 ( 4.3A)
 0.73A 4fp9C-5ltmB:
undetectable		 4fp9C-5ltmB:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_A_RBFA402_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		5 / 12 ALA B 124
ALA B 220
ILE B 182
LEU B 181
MET B 147
 None
 1.07A 4r3aA-5ltmB:
undetectable		 4r3aA-5ltmB:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DX3_A_ESTA601_1
(ESTROGEN RECEPTOR)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		5 / 10 LEU B 214
GLU B 217
LEU B 143
GLY B 183
LEU B 184
 None
 1.36A 5dx3A-5ltmB:
undetectable		 5dx3A-5ltmB:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWZ_B_BEZB301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		3 / 3 MET B 481
GLN B 485
ARG B 516
 None
 0.84A 5ewzB-5ltmB:
3.0		 5ewzB-5ltmB:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_G_SAMG301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		5 / 12 ALA B 507
ASP B 296
GLN B 262
THR B 260
SER B 286
 None
 1.40A 5hfjG-5ltmB:
undetectable		 5hfjG-5ltmB:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		4 / 8 THR B 178
SER B 226
ALA B 220
SER B 137
 None
 1.12A 5l5fY-5ltmB:
undetectable
5l5fZ-5ltmB:
undetectable		 5l5fY-5ltmB:
17.44
5l5fZ-5ltmB:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		5 / 10 THR B 178
SER B 226
GLY B 218
ALA B 220
SER B 137
 None
 1.12A 5l66K-5ltmB:
undetectable
5l66L-5ltmB:
undetectable		 5l66K-5ltmB:
17.07
5l66L-5ltmB:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		5 / 10 THR B 178
SER B 226
GLY B 218
ALA B 220
SER B 137
 None
 1.13A 5l66Y-5ltmB:
undetectable
5l66Z-5ltmB:
undetectable		 5l66Y-5ltmB:
17.07
5l66Z-5ltmB:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M35_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		3 / 3 MET B 481
GLN B 485
ARG B 516
 None
 0.84A 5m35B-5ltmB:
undetectable		 5m35B-5ltmB:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M36_A_BEZA303_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		3 / 3 MET B 481
GLN B 485
ARG B 516
 None
 0.77A 5m36A-5ltmB:
3.4		 5m36A-5ltmB:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_B_TESB502_1
(-)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		5 / 12 LEU B 118
VAL B 190
MET B 125
ALA B 202
LEU B 181
 None
 1.14A 5og9B-5ltmB:
undetectable		 5og9B-5ltmB:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		3 / 3 TYR B 176
ALA B 112
TYR B 160
 None
 0.80A 5uunB-5ltmB:
undetectable		 5uunB-5ltmB:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXC_A_ZITA306_1
(PREDICTED
AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		4 / 7 THR B  46
ARG B  40
ASP B  37
LEU B  33
 None
 0.98A 5uxcA-5ltmB:
1.4		 5uxcA-5ltmB:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_A_C2FA3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		5 / 12 GLY B 329
VAL B 476
LEU B 386
GLY B 380
ILE B 379
 None
 1.10A 5vooA-5ltmB:
undetectable		 5vooA-5ltmB:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_B_C2FB702_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		5 / 12 GLY B 329
VAL B 476
LEU B 386
GLY B 380
ILE B 379
 None
 1.12A 5vooB-5ltmB:
undetectable		 5vooB-5ltmB:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_C_C2FC702_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		5 / 12 GLY B 329
VAL B 476
LEU B 386
GLY B 380
ILE B 379
 None
 1.12A 5vooC-5ltmB:
undetectable		 5vooC-5ltmB:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_B_DAHB60_1
(PUTATIVE CYTOCHROME
C)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		4 / 5 HIS B 132
MET B 222
ASN B 362
LEU B 174
 None
 1.44A 5xdhB-5ltmB:
undetectable		 5xdhB-5ltmB:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		4 / 6 ARG B 490
GLN B 485
PHE B 482
LEU B 257
 None
 1.06A 5z84P-5ltmB:
3.8
5z84W-5ltmB:
undetectable		 5z84P-5ltmB:
18.82
5z84W-5ltmB:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		4 / 6 ARG B 490
GLN B 485
PHE B 482
LEU B 257
 None
 1.08A 5z85P-5ltmB:
3.8
5z85W-5ltmB:
1.4		 5z85P-5ltmB:
18.82
5z85W-5ltmB:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		4 / 6 ARG B 490
GLN B 485
PHE B 482
LEU B 257
 None
 1.06A 5z86C-5ltmB:
3.8
5z86J-5ltmB:
undetectable		 5z86C-5ltmB:
18.82
5z86J-5ltmB:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		4 / 6 ARG B 490
GLN B 485
PHE B 482
LEU B 257
 None
 1.04A 5z86P-5ltmB:
3.8
5z86W-5ltmB:
1.4		 5z86P-5ltmB:
18.82
5z86W-5ltmB:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		4 / 6 ARG B 490
GLN B 485
PHE B 482
LEU B 257
 None
 1.08A 5zcpC-5ltmB:
3.8
5zcpJ-5ltmB:
undetectable		 5zcpC-5ltmB:
18.82
5zcpJ-5ltmB:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		4 / 6 ARG B 490
GLN B 485
PHE B 482
LEU B 257
 None
 1.06A 5zcpP-5ltmB:
3.7
5zcpW-5ltmB:
undetectable		 5zcpP-5ltmB:
18.82
5zcpW-5ltmB:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FN9_A_BEZA302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		3 / 3 MET B 481
GLN B 485
ARG B 516
 None
 0.82A 6fn9A-5ltmB:
3.2		 6fn9A-5ltmB:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNA_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		3 / 3 MET B 481
GLN B 485
ARG B 516
 None
 0.88A 6fnaB-5ltmB:
3.2		 6fnaB-5ltmB:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNB_A_BEZA301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		3 / 3 MET B 481
GLN B 485
ARG B 516
 None
 0.80A 6fnbA-5ltmB:
3.3		 6fnbA-5ltmB:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ltm PHENYLALANINE
AMMONIA LYASE
(Anabaena) 		4 / 6 ARG B 490
GLN B 485
PHE B 482
LEU B 257
 None
 1.12A 6nmpC-5ltmB:
undetectable
6nmpJ-5ltmB:
undetectable		 6nmpC-5ltmB:
18.82
6nmpJ-5ltmB:
8.09