SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ltq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EII_A_RTLA135_1
(CELLULAR
RETINOL-BINDING
PROTEIN II)		 5ltq GREEN FLUORESCENT
PROTEIN BLFP-Y3
(Branchiostoma
lanceolatum) 		4 / 7 TYR A 175
GLN A  63
TYR A 102
GLN A 212
 None
 1.15A 1eiiA-5ltqA:
undetectable		 1eiiA-5ltqA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRK_A_TFPA204_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5ltq GREEN FLUORESCENT
PROTEIN BLFP-Y3
(Branchiostoma
lanceolatum) 		5 / 9 PHE A  15
VAL A 117
PHE A 122
SER A 169
LEU A  53
 None
 1.42A 1wrkA-5ltqA:
undetectable
1wrkB-5ltqA:
undetectable		 1wrkA-5ltqA:
16.23
1wrkB-5ltqA:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOX_A_THAA400_1
(HISTAMINE
N-METHYLTRANSFERASE)		 5ltq GREEN FLUORESCENT
PROTEIN BLFP-Y3
(Branchiostoma
lanceolatum) 		4 / 8 PHE A 208
GLU A 210
TYR A 102
TYR A 104
 CR2  A  59 ( 4.6A)
CR2  A  59 ( 3.2A)
None
CR2  A  59 ( 4.6A)
 1.34A 2aoxA-5ltqA:
undetectable		 2aoxA-5ltqA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6F_C_010C6_0
(INFECTIOUS
BRONCHITIS VIRUS
(IBV) MAIN PROTEASE
N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE)		 5ltq GREEN FLUORESCENT
PROTEIN BLFP-Y3
(Branchiostoma
lanceolatum) 		3 / 3 ASN A 207
LEU A 199
HIS A 201
 None
 0.82A 2q6fB-5ltqA:
undetectable		 2q6fB-5ltqA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBZ_A_VDXA501_1
(CYTOCHROME P450-SU1)		 5ltq GREEN FLUORESCENT
PROTEIN BLFP-Y3
(Branchiostoma
lanceolatum) 		5 / 11 THR A 120
LEU A  53
SER A  41
MET A  22
ILE A  11
 None
 0.82A 2zbzA-5ltqA:
undetectable		 2zbzA-5ltqA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CD2_A_MTXA307_1
(DIHYDROFOLATE
REDUCTASE)		 5ltq GREEN FLUORESCENT
PROTEIN BLFP-Y3
(Branchiostoma
lanceolatum) 		5 / 12 ILE A  57
LEU A  98
SER A  49
ILE A  11
TYR A 102
 CR2  A  59 ( 4.2A)
None
None
None
None
 1.18A 3cd2A-5ltqA:
undetectable		 3cd2A-5ltqA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D4S_A_TIMA401_2
(BETA-2 ADRENERGIC
RECEPTOR/T4-LYSOZYME
CHIMERA)		 5ltq GREEN FLUORESCENT
PROTEIN BLFP-Y3
(Branchiostoma
lanceolatum) 		3 / 3 THR A 173
SER A 153
PHE A 177
 CL  A 301 ( 4.0A)
CL  A 301 (-2.8A)
None
 0.80A 3d4sA-5ltqA:
undetectable		 3d4sA-5ltqA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SEL_X_DXCX75_0
(CYTOCHROME C7)		 5ltq GREEN FLUORESCENT
PROTEIN BLFP-Y3
(Branchiostoma
lanceolatum) 		4 / 8 LEU A  53
LYS A  43
PHE A  20
GLY A  13
 None
 1.01A 3selX-5ltqA:
undetectable		 3selX-5ltqA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ1_X_DXCX75_0
(CYTOCHROME C7)		 5ltq GREEN FLUORESCENT
PROTEIN BLFP-Y3
(Branchiostoma
lanceolatum) 		4 / 6 LEU A  53
LYS A  43
PHE A  20
GLY A  13
 None
 0.93A 3sj1X-5ltqA:
undetectable		 3sj1X-5ltqA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ4_X_DXCX75_0
(CYTOCHROME C7)		 5ltq GREEN FLUORESCENT
PROTEIN BLFP-Y3
(Branchiostoma
lanceolatum) 		5 / 9 ILE A  57
LEU A  53
LYS A  43
PHE A  20
GLY A  13
 CR2  A  59 ( 4.2A)
None
None
None
None
 1.39A 3sj4X-5ltqA:
undetectable		 3sj4X-5ltqA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WCX_C_SAMC503_0
(BIOTIN AND THIAMIN
SYNTHESIS ASSOCIATED)		 5ltq GREEN FLUORESCENT
PROTEIN BLFP-Y3
(Branchiostoma
lanceolatum) 		5 / 12 TYR A  64
TYR A 104
GLY A 113
GLU A   8
HIS A  62
 None
CR2  A  59 ( 4.6A)
None
None
CR2  A  59 (-4.1A)
 1.02A 4wcxC-5ltqA:
undetectable		 4wcxC-5ltqA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WCX_C_SAMC503_0
(BIOTIN AND THIAMIN
SYNTHESIS ASSOCIATED)		 5ltq GREEN FLUORESCENT
PROTEIN BLFP-Y3
(Branchiostoma
lanceolatum) 		5 / 12 TYR A  64
TYR A 104
GLY A 113
PHE A 208
HIS A  62
 None
CR2  A  59 ( 4.6A)
None
CR2  A  59 ( 4.6A)
CR2  A  59 (-4.1A)
 1.06A 4wcxC-5ltqA:
undetectable		 4wcxC-5ltqA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WCX_C_SAMC503_0
(BIOTIN AND THIAMIN
SYNTHESIS ASSOCIATED)		 5ltq GREEN FLUORESCENT
PROTEIN BLFP-Y3
(Branchiostoma
lanceolatum) 		5 / 12 TYR A 104
GLY A 113
GLU A   8
PRO A  30
ALA A  77
 CR2  A  59 ( 4.6A)
None
None
None
None
 1.21A 4wcxC-5ltqA:
undetectable		 4wcxC-5ltqA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZF8_A_MYTA502_1
(BIFUNCTIONAL
P-450/NADPH-P450
REDUCTASE)		 5ltq GREEN FLUORESCENT
PROTEIN BLFP-Y3
(Branchiostoma
lanceolatum) 		4 / 6 LEU A 206
ILE A  57
THR A 197
ALA A 136
 None
CR2  A  59 ( 4.2A)
CR2  A  59 ( 4.7A)
None
 0.78A 4zf8A-5ltqA:
undetectable		 4zf8A-5ltqA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5ltq GREEN FLUORESCENT
PROTEIN BLFP-Y3
(Branchiostoma
lanceolatum) 		4 / 5 PHE A  61
LEU A  39
GLY A  24
ILE A 111
 CR2  A  59 ( 3.6A)
None
None
None
 0.96A 5ik1A-5ltqA:
undetectable		 5ik1A-5ltqA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5ltq GREEN FLUORESCENT
PROTEIN BLFP-Y3
(Branchiostoma
lanceolatum) 		3 / 3 SER A  14
LEU A  39
MET A  22
 None
 0.82A 5ikrB-5ltqA:
undetectable		 5ikrB-5ltqA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM3_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 5ltq GREEN FLUORESCENT
PROTEIN BLFP-Y3
(Branchiostoma
lanceolatum) 		4 / 6 SER A  14
PHE A  20
ASP A  19
HIS A  10
 None
 0.99A 5om3A-5ltqA:
undetectable
5om3B-5ltqA:
undetectable		 5om3A-5ltqA:
17.92
5om3B-5ltqA:
9.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA608_0
(ALPHA-AMYLASE)		 5ltq GREEN FLUORESCENT
PROTEIN BLFP-Y3
(Branchiostoma
lanceolatum) 		4 / 6 PHE A 115
GLY A 113
GLN A  63
TYR A 106
 CR2  A  59 ( 4.5A)
None
None
None
 1.25A 6ag0A-5ltqA:
undetectable		 6ag0A-5ltqA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC606_0
(ALPHA-AMYLASE)		 5ltq GREEN FLUORESCENT
PROTEIN BLFP-Y3
(Branchiostoma
lanceolatum) 		4 / 6 PHE A 115
GLY A 113
GLN A  63
TYR A 106
 CR2  A  59 ( 4.5A)
None
None
None
 1.23A 6ag0C-5ltqA:
undetectable		 6ag0C-5ltqA:
14.89