SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ltv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7Q_A_BEZA600_0
(COCAINE ESTERASE)		 5ltv CHEMOTACTIC
TRANSDUCER PCTC
(Pseudomonas
aeruginosa) 		5 / 10 TYR A 196
ALA A 262
PRO A 228
PHE A 248
LEU A 219
 None
 1.26A 1l7qA-5ltvA:
0.0		 1l7qA-5ltvA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5ltv CHEMOTACTIC
TRANSDUCER PCTC
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  50
THR A  51
ALA A 197
GLY A 233
SER A 247
 None
 1.31A 1nbiC-5ltvA:
undetectable		 1nbiC-5ltvA:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_B_ADNB902_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 5ltv CHEMOTACTIC
TRANSDUCER PCTC
(Pseudomonas
aeruginosa) 		5 / 11 PHE A 198
THR A 218
ALA A 220
VAL A 264
TYR A 196
 None
 1.39A 2gl0B-5ltvA:
undetectable
2gl0C-5ltvA:
undetectable		 2gl0B-5ltvA:
21.74
2gl0C-5ltvA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_C_ADNC903_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 5ltv CHEMOTACTIC
TRANSDUCER PCTC
(Pseudomonas
aeruginosa) 		5 / 12 THR A 218
ALA A 220
VAL A 264
TYR A 196
PHE A 198
 None
 1.40A 2gl0A-5ltvA:
undetectable
2gl0C-5ltvA:
undetectable		 2gl0A-5ltvA:
21.74
2gl0C-5ltvA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_D_ADND904_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 5ltv CHEMOTACTIC
TRANSDUCER PCTC
(Pseudomonas
aeruginosa) 		5 / 12 PHE A 198
THR A 218
ALA A 220
VAL A 264
TYR A 196
 None
 1.37A 2gl0D-5ltvA:
undetectable
2gl0E-5ltvA:
undetectable		 2gl0D-5ltvA:
21.74
2gl0E-5ltvA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_F_ADNF906_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 5ltv CHEMOTACTIC
TRANSDUCER PCTC
(Pseudomonas
aeruginosa) 		5 / 11 THR A 218
ALA A 220
VAL A 264
TYR A 196
PHE A 198
 None
 1.36A 2gl0D-5ltvA:
undetectable
2gl0F-5ltvA:
undetectable		 2gl0D-5ltvA:
21.74
2gl0F-5ltvA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_A_ACTA1397_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 5ltv CHEMOTACTIC
TRANSDUCER PCTC
(Pseudomonas
aeruginosa) 		3 / 3 PRO A 126
GLY A 105
TYR A 132
 None
 0.54A 2vouA-5ltvA:
undetectable		 2vouA-5ltvA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_B_ACTB1391_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 5ltv CHEMOTACTIC
TRANSDUCER PCTC
(Pseudomonas
aeruginosa) 		3 / 3 PRO A 126
GLY A 105
TYR A 132
 None
 0.57A 2vouB-5ltvA:
undetectable		 2vouB-5ltvA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_C_ACTC1391_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 5ltv CHEMOTACTIC
TRANSDUCER PCTC
(Pseudomonas
aeruginosa) 		3 / 3 PRO A 126
GLY A 105
TYR A 132
 None
 0.56A 2vouC-5ltvA:
undetectable		 2vouC-5ltvA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_A_SAMA601_0
(HYPOTHETICAL PROTEIN)		 5ltv CHEMOTACTIC
TRANSDUCER PCTC
(Pseudomonas
aeruginosa) 		5 / 12 THR A 144
ILE A 142
GLY A 175
ALA A 135
LEU A 161
 None
 1.08A 2yvlA-5ltvA:
undetectable		 2yvlA-5ltvA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_B_SAMB602_0
(HYPOTHETICAL PROTEIN)		 5ltv CHEMOTACTIC
TRANSDUCER PCTC
(Pseudomonas
aeruginosa) 		5 / 12 THR A 144
ILE A 142
GLY A 175
ALA A 135
LEU A 161
 None
 1.07A 2yvlB-5ltvA:
undetectable		 2yvlB-5ltvA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_D_NCTD501_1
(CYTOCHROME P450 2A13)		 5ltv CHEMOTACTIC
TRANSDUCER PCTC
(Pseudomonas
aeruginosa) 		4 / 6 ASN A  56
ALA A  54
THR A 249
LEU A 263
 None
 1.05A 4ejgD-5ltvA:
undetectable		 4ejgD-5ltvA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_H_SAMH501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 5ltv CHEMOTACTIC
TRANSDUCER PCTC
(Pseudomonas
aeruginosa) 		5 / 10 LEU A  71
GLY A 175
LEU A  75
VAL A 172
LEU A 104
 None
 1.07A 5o96G-5ltvA:
undetectable
5o96H-5ltvA:
undetectable		 5o96G-5ltvA:
22.65
5o96H-5ltvA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_A_BEZA502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 5ltv CHEMOTACTIC
TRANSDUCER PCTC
(Pseudomonas
aeruginosa) 		4 / 6 VAL A 261
LEU A 207
LEU A 208
HIS A 209
 None
 0.95A 6e43A-5ltvA:
undetectable		 6e43A-5ltvA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_B_BEZB502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 5ltv CHEMOTACTIC
TRANSDUCER PCTC
(Pseudomonas
aeruginosa) 		4 / 6 VAL A 261
LEU A 207
LEU A 208
HIS A 209
 None
 0.99A 6e43B-5ltvA:
undetectable		 6e43B-5ltvA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_C_BEZC502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 5ltv CHEMOTACTIC
TRANSDUCER PCTC
(Pseudomonas
aeruginosa) 		4 / 6 VAL A 261
LEU A 207
LEU A 208
HIS A 209
 None
 0.98A 6e43C-5ltvA:
undetectable		 6e43C-5ltvA:
22.51