SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5lug'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB8_0
(GRAMICIDIN A)		 5lug SPINDLIN-LIKE
PROTEIN 2, ISOFORM
CRA_A
(Homo
sapiens) 		4 / 5 VAL A  50
GLY A  51
VAL A  72
TRP A 161
 None
 1.18A 1tkqB-5lugA:
undetectable		 1tkqB-5lugA:
4.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_E_SC2E1289_1
(FICOLIN-2)		 5lug SPINDLIN-LIKE
PROTEIN 2, ISOFORM
CRA_A
(Homo
sapiens) 		4 / 6 ASP A 112
ARG A  53
THR A  71
ASP A  88
 None
 1.17A 2j2pE-5lugA:
undetectable
2j2pF-5lugA:
undetectable		 2j2pE-5lugA:
18.33
2j2pF-5lugA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDT_B_VORB506_1
(CHOLESTEROL
24-HYDROXYLASE)		 5lug SPINDLIN-LIKE
PROTEIN 2, ISOFORM
CRA_A
(Homo
sapiens) 		5 / 11 TYR A 181
LEU A 178
PHE A 162
ILE A 119
ALA A 122
 None
 0.97A 3mdtB-5lugA:
undetectable		 3mdtB-5lugA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_E_CLME221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5lug SPINDLIN-LIKE
PROTEIN 2, ISOFORM
CRA_A
(Homo
sapiens) 		3 / 3 PHE A 247
CYH A  92
HIS A 248
 None
 0.94A 3u9fF-5lugA:
undetectable		 3u9fF-5lugA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_I_CLMI221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5lug SPINDLIN-LIKE
PROTEIN 2, ISOFORM
CRA_A
(Homo
sapiens) 		3 / 3 PHE A 247
CYH A  92
HIS A 248
 None
 1.02A 3u9fG-5lugA:
undetectable		 3u9fG-5lugA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_R_CLMR221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5lug SPINDLIN-LIKE
PROTEIN 2, ISOFORM
CRA_A
(Homo
sapiens) 		3 / 3 PHE A 247
CYH A  92
HIS A 248
 None
 0.98A 3u9fS-5lugA:
undetectable		 3u9fS-5lugA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IMS_B_ACTB713_0
(ACETOLACTATE
SYNTHASE CATALYTIC
SUBUNIT,
MITOCHONDRIAL)		 5lug SPINDLIN-LIKE
PROTEIN 2, ISOFORM
CRA_A
(Homo
sapiens) 		3 / 3 GLY A 208
GLN A 231
LYS A 212
 None
 0.76A 5imsB-5lugA:
undetectable		 5imsB-5lugA:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9Y_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)		 5lug SPINDLIN-LIKE
PROTEIN 2, ISOFORM
CRA_A
(Homo
sapiens) 		3 / 3 LYS A 235
PRO A 236
LYS A 204
 None
 1.33A 5y9yA-5lugA:
undetectable		 5y9yA-5lugA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRZ_A_H8JA1206_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 5lug SPINDLIN-LIKE
PROTEIN 2, ISOFORM
CRA_A
(Homo
sapiens) 		5 / 12 VAL A 255
LEU A 254
PHE A 264
GLY A 211
VAL A 232
 None
 1.10A 6drzA-5lugA:
undetectable		 6drzA-5lugA:
19.26