SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5lum'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_A_CHDA502_0
(FERROCHELATASE)		 5lum HEAT SHOCK PROTEIN
BETA-6
(Homo
sapiens) 		4 / 8 ARG A 122
PRO A 148
VAL A 127
GLY A 126
 None
 0.97A 2qd3A-5lumA:
undetectable		 2qd3A-5lumA:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_I_CLMI221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5lum HEAT SHOCK PROTEIN
BETA-6
(Homo
sapiens) 		5 / 10 PHE A  83
LEU A 142
VAL A  99
PHE A 117
VAL A  80
 None
None
None
SO4  A 201 ( 4.6A)
None
 1.31A 3u9fI-5lumA:
undetectable		 3u9fI-5lumA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_J_CLMJ221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5lum HEAT SHOCK PROTEIN
BETA-6
(Homo
sapiens) 		5 / 12 PHE A  83
LEU A 142
VAL A  99
PHE A 117
VAL A  80
 None
None
None
SO4  A 201 ( 4.6A)
None
 1.31A 3u9fJ-5lumA:
undetectable
3u9fK-5lumA:
undetectable		 3u9fJ-5lumA:
19.16
3u9fK-5lumA:
19.16