SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5lut'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5lut BLM HELICASE
(Gallus
gallus) 		4 / 8 LYS A 343
LEU A 346
GLN A 347
LEU A 333
 None
 0.75A 1v54P-5lutA:
undetectable
1v54W-5lutA:
undetectable		 1v54P-5lutA:
12.60
1v54W-5lutA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5lut BLM HELICASE
(Gallus
gallus) 		4 / 7 LYS A 343
LEU A 346
GLN A 347
LEU A 333
 None
 0.71A 1v55C-5lutA:
undetectable
1v55J-5lutA:
undetectable		 1v55C-5lutA:
12.60
1v55J-5lutA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5lut BLM HELICASE
(Gallus
gallus) 		4 / 7 LYS A 343
LEU A 346
GLN A 347
LEU A 333
 None
 0.69A 2dysP-5lutA:
undetectable
2dysW-5lutA:
undetectable		 2dysP-5lutA:
12.60
2dysW-5lutA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5lut BLM HELICASE
(Gallus
gallus) 		4 / 8 LYS A 343
LEU A 346
GLN A 347
LEU A 333
 None
 0.71A 2eikP-5lutA:
undetectable
2eikW-5lutA:
undetectable		 2eikP-5lutA:
12.60
2eikW-5lutA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5lut BLM HELICASE
(Gallus
gallus) 		4 / 8 LYS A 343
LEU A 346
GLN A 347
LEU A 333
 None
 0.68A 2eilC-5lutA:
undetectable
2eilJ-5lutA:
undetectable		 2eilC-5lutA:
12.60
2eilJ-5lutA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5lut BLM HELICASE
(Gallus
gallus) 		4 / 7 LYS A 343
LEU A 346
GLN A 347
LEU A 333
 None
 0.70A 2eimC-5lutA:
undetectable
2eimJ-5lutA:
undetectable		 2eimC-5lutA:
12.60
2eimJ-5lutA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5lut BLM HELICASE
(Gallus
gallus) 		4 / 7 LYS A 343
LEU A 346
GLN A 347
LEU A 333
 None
 0.75A 2einC-5lutA:
undetectable
2einJ-5lutA:
undetectable		 2einC-5lutA:
12.60
2einJ-5lutA:
24.59