SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5lv1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_2
(ADENOSINE DEAMINASE)		 5lv1 PTXB
(Prochlorococcus
marinus) 		4 / 5 LEU A 139
LEU A 135
LEU A  79
GLY A 260
 None
 0.70A 1a4lC-5lv1A:
undetectable		 1a4lC-5lv1A:
11.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRQ_A_STRA501_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 5lv1 PTXB
(Prochlorococcus
marinus) 		5 / 11 LEU A 267
GLU A  60
VAL A 271
ILE A  59
LEU A  75
 None
 1.14A 1mrqA-5lv1A:
undetectable		 1mrqA-5lv1A:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_B_SAMB293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5lv1 PTXB
(Prochlorococcus
marinus) 		5 / 12 TYR A 100
ALA A 164
ASP A 161
ILE A 256
TYR A  55
 78T  A 301 (-4.9A)
None
None
None
78T  A 301 (-4.6A)
 1.48A 1xvaB-5lv1A:
undetectable		 1xvaB-5lv1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		 5lv1 PTXB
(Prochlorococcus
marinus) 		4 / 8 ILE A 105
ILE A 104
VAL A 167
ILE A 118
 None
 0.63A 3p4wC-5lv1A:
undetectable		 3p4wC-5lv1A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ1_X_DXCX75_0
(CYTOCHROME C7)		 5lv1 PTXB
(Prochlorococcus
marinus) 		4 / 6 ILE A 104
LEU A 141
PHE A 152
GLY A 154
 None
 1.06A 3sj1X-5lv1A:
undetectable		 3sj1X-5lv1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQF_A_CZEA613_1
(SERUM ALBUMIN)		 5lv1 PTXB
(Prochlorococcus
marinus) 		5 / 9 ALA A 129
LEU A 125
GLY A 126
LEU A  75
GLU A 138
 None
 1.19A 5dqfA-5lv1A:
undetectable		 5dqfA-5lv1A:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_B_SAMB303_1
(METHYLTRANSFERASE)		 5lv1 PTXB
(Prochlorococcus
marinus) 		4 / 7 GLY A 158
PHE A 156
SER A 133
ASP A 127
 None
None
78T  A 301 ( 4.6A)
None
 1.00A 5n5dB-5lv1A:
2.3		 5n5dB-5lv1A:
undetectable