SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5lvc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_A_VIBA502_1
(THIAMIN
PYROPHOSPHOKINASE)		 5lvc VP1
(Aichivirus
A) 		4 / 8 LEU a 202
SER a 110
ASN a 111
ASP a 211
 None
 0.88A 1ig3A-5lvca:
3.2
1ig3B-5lvca:
undetectable		 1ig3A-5lvca:
23.37
1ig3B-5lvca:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_B_VIBB501_1
(THIAMIN
PYROPHOSPHOKINASE)		 5lvc VP1
(Aichivirus
A) 		4 / 7 ASP a 211
LEU a 202
SER a 110
ASN a 111
 None
 0.93A 1ig3A-5lvca:
3.2
1ig3B-5lvca:
undetectable		 1ig3A-5lvca:
23.37
1ig3B-5lvca:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		 5lvc VP1
(Aichivirus
A) 		4 / 8 ILE a 170
PHE a 220
LEU a  81
LEU a  93
 None
 0.84A 2w98B-5lvca:
undetectable		 2w98B-5lvca:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_B_HCZB262_1
(GLUTAMATE RECEPTOR 2)		 5lvc VP1
(Aichivirus
A) 		5 / 10 ILE a  89
PRO a  54
GLY a  88
LEU a  93
SER a  94
 None
 0.95A 3ik6B-5lvca:
undetectable
3ik6E-5lvca:
undetectable		 3ik6B-5lvca:
22.39
3ik6E-5lvca:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UUD_A_ESTA600_1
(ESTROGEN RECEPTOR)		 5lvc VP1
(Aichivirus
A) 		5 / 11 LEU a 196
ALA a 122
LEU a 120
MET a 119
GLY a  70
 None
 1.21A 3uudA-5lvca:
undetectable		 3uudA-5lvca:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_A_ADNA500_2
(SUGAR KINASE PROTEIN)		 5lvc VP1
(Aichivirus
A) 		4 / 4 SER a 165
TYR a 163
GLY a 194
PRO a 125
 None
 1.48A 4e3aA-5lvca:
undetectable		 4e3aA-5lvca:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOG_A_C2FA302_0
(THYMIDYLATE SYNTHASE)		 5lvc VP1
(Aichivirus
A) 		5 / 11 ILE a  99
LEU a  75
ASP a 102
GLY a 221
PHE a 223
 None
 1.21A 4fogA-5lvca:
undetectable		 4fogA-5lvca:
25.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 5lvc VP1
(Aichivirus
A) 		5 / 10 LEU a 196
ALA a 122
LEU a 120
MET a 119
GLY a  70
 None
 1.21A 5dxbA-5lvca:
undetectable		 5dxbA-5lvca:
21.67