SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5lvy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PW7_B_RABB646_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lvy ADHESIN PROTEIN
(Escherichia
coli) 		5 / 9 SER A 155
GLY A 157
VAL A 122
GLU A 123
ILE A  34
 None
 1.48A 1pw7B-5lvyA:
undetectable		 1pw7B-5lvyA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE9_A_BEZA352_0
(D-AMINO ACID OXIDASE)		 5lvy ADHESIN PROTEIN
(Escherichia
coli) 		4 / 5 TYR A 115
TYR A 120
ILE A 159
GLY A 114
 None
 1.34A 1ve9A-5lvyA:
undetectable		 1ve9A-5lvyA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_C_ADNC252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lvy ADHESIN PROTEIN
(Escherichia
coli) 		5 / 11 SER A 155
GLY A 157
VAL A 122
GLU A 123
ILE A  34
 None
 1.46A 1vhwC-5lvyA:
undetectable
1vhwE-5lvyA:
undetectable		 1vhwC-5lvyA:
23.35
1vhwE-5lvyA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_D_ADND252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lvy ADHESIN PROTEIN
(Escherichia
coli) 		5 / 11 SER A 155
GLY A 157
VAL A 122
GLU A 123
ILE A  34
 None
 1.47A 1vhwA-5lvyA:
undetectable
1vhwD-5lvyA:
undetectable		 1vhwA-5lvyA:
23.35
1vhwD-5lvyA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_E_ADNE252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lvy ADHESIN PROTEIN
(Escherichia
coli) 		5 / 11 SER A 155
GLY A 157
VAL A 122
GLU A 123
ILE A  34
 None
 1.47A 1vhwC-5lvyA:
undetectable
1vhwE-5lvyA:
undetectable		 1vhwC-5lvyA:
23.35
1vhwE-5lvyA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_J_BEZJ3352_0
(D-AMINO-ACID OXIDASE)		 5lvy ADHESIN PROTEIN
(Escherichia
coli) 		4 / 5 TYR A 115
TYR A 120
ILE A 159
GLY A 114
 None
 1.32A 2du8J-5lvyA:
undetectable		 2du8J-5lvyA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UVN_A_ECNA1409_1
(CYTOCHROME P450 130)		 5lvy ADHESIN PROTEIN
(Escherichia
coli) 		5 / 12 THR A  77
THR A  78
GLY A  89
GLY A  90
LEU A  38
 None
 1.19A 2uvnA-5lvyA:
undetectable		 2uvnA-5lvyA:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_0
(MNMC2)		 5lvy ADHESIN PROTEIN
(Escherichia
coli) 		5 / 12 GLY A  80
TYR A  33
ASN A  35
PHE A  54
LEU A  13
 None
 1.11A 3vywA-5lvyA:
undetectable		 3vywA-5lvyA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZPH_A_PRLA501_0
(ARYL HYDROCARBON
RECEPTOR NUCLEAR
TRANSLOCATOR
ENDOTHELIAL PAS
DOMAIN-CONTAINING
PROTEIN 1)		 5lvy ADHESIN PROTEIN
(Escherichia
coli) 		4 / 7 VAL A  52
GLN A 103
LEU A  38
SER A  14
 None
 0.98A 4zphA-5lvyA:
undetectable
4zphB-5lvyA:
undetectable		 4zphA-5lvyA:
16.67
4zphB-5lvyA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N7F_A_RBFA502_0
(PUTATIVE GLUTATHIONE
REDUCTASE (GR))		 5lvy ADHESIN PROTEIN
(Escherichia
coli) 		4 / 7 GLY A  81
TYR A  79
HIS A  95
GLY A  92
 None
 0.73A 6n7fA-5lvyA:
undetectable		 6n7fA-5lvyA:
17.73